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Osphos
Dirt Dobber
Reg. Jun 2009
Posted 2018-05-12 7:21 AM
Subject: Osphos


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 Anyone want to share their experience with Osphos? Were you told the horse would have come off Previcox.  I did a search but would like more feedback if there is any. 
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emricmacy
Reg. Sep 2016
Posted 2018-05-12 8:55 AM
Subject: RE: Osphos



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Dirt Dobber - 2018-05-12 7:21 AM

 Anyone want to share their experience with Osphos? Were you told the horse would have come off Previcox.  I did a search but would like more feedback if there is any. 

My vet gave my gelding Osphos on 5/1/18. Have not seen any results yet. Yes, I had to pull him off of previcox for a week before the shot. Absolutely no bute/previcox a week before the shot.
We sedated my gelding as he's not the best with multiple shots. He did great, absolutely no side effects. We did one shot on each side of the neck, and one in the chest. After he came out of sedation he went back outside in the pasture.
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Chandler's Mom
Reg. Jan 2015
Posted 2018-05-12 10:48 PM
Subject: RE: Osphos



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Dirt Dobber
Reg. Jun 2009
Posted 2018-05-13 9:07 AM
Subject: RE: Osphos


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My story is we did the injection last year and my horse went 100% sound in 6 weeks.  The first injection he had some mild cramping and was lethargic for a few days but bounced right back.  We injected him again last week because we made the mistake of switching the pad material the last shoeing and he bruised his navicular bone with the cyst.  This time around he was very agitated, grinding his teeth and shaking his head.  It went on for 24 hours.  He is ok today. He has never been on previcox but the vet gave it to him this time to start to get the inflammation down.
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NipntuckLR
Reg. Mar 2005
Posted 2018-05-13 11:22 AM
Subject: RE: Osphos



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Yes, I was told no previcox or bute for I think four days before and after the shot. My vet also said that the rep for Osphos told him there is absolutely no set time to give another shot. I have heard many people say it should be given every six months. Apparently the rep said don't give another shot until it is needed.
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MidWest1452
Reg. May 2013
Posted 2018-05-13 12:23 PM
Subject: RE: Osphos



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 A video worth watching if considering Osphos. If you have looked up past threads then I won't state my opinion again on them. 

Video Link:

https://vimeo.com/257695901
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hlc84
Reg. Nov 2012
Posted 2018-05-13 12:41 PM
Subject: RE: Osphos


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Have used for a foot/heel sore horse for with great results. Horse wasn’t on previcox. Depending on what your treating if you get results with osphos, i wouldn’t see why the horse couldn’t come off or lessen what you’re giving.
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Meep.Meep
Reg. Jun 2017
Posted 2018-05-13 1:06 PM
Subject: RE: Osphos


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MidWest1452 - 2018-05-13 12:23 PM

 A video worth watching if considering Osphos. If you have looked up past threads then I won't state my opinion again on them. 

Video Link:

https://vimeo.com/257695901

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Dirt Dobber
Reg. Jun 2009
Posted 2018-05-13 5:00 PM
Subject: RE: Osphos


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MidWest1452 - 2018-05-13 12:23 PM  A video worth watching if considering Osphos. If you have looked up past threads then I won't state my opinion again on them. 



Video Link:


https://vimeo.com/257695901

I saw the video before doing the Osphos the first time.  Thanks for sharing.  
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TheDutchMan01
Reg. Jan 2010
Posted 2018-05-14 8:35 AM
Subject: RE: Osphos


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NipntuckLR - 2018-05-13 11:22 AM

Yes, I was told no previcox or bute for I think four days before and after the shot. My vet also said that the rep for Osphos told him there is absolutely no set time to give another shot. I have heard many people say it should be given every six months. Apparently the rep said don't give another shot until it is needed.

My vet said no bute, banamine, or Previcox for 2 weeks. He also said to get another shot in 6 months and then yearly. However, I don't think I'm going to. We gave it experimentally and so far the benefit is not out weighing the side effects. My horse does feel great its just not done much for the pain we were initially trying to treat....yet.
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Herbie
Reg. Oct 2003
Posted 2018-05-14 9:23 AM
Subject: RE: Osphos


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If you haven't read the article by Rood & Riddle regarding biophosphonate use, do it before you choose to go that route.  Here are a couple articles to get you started.  Educate yourself as to the potential long term effects exceeding the right now.  I'm not advising anyone not to use it, i'm advising anyone considering to do their homework.   https://www.paulickreport.com/horse-care-category/bramlage-price-pay-bisphosphonate-use-delayed-healing/    https://www.paulickreport.com/horse-care-category/bramlage-price-pay-bisphosphonate-use-delayed-healing/
 
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Dirt Dobber
Reg. Jun 2009
Posted 2018-05-14 6:03 PM
Subject: RE: Osphos


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It appears I have done my homework and my vet has advised me well. 
I am guessing the videos and articles are posted by those who had bad experiences with osphos.  I hope your horses are doing better.
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MidWest1452
Reg. May 2013
Posted 2018-05-14 9:40 PM
Subject: RE: Osphos



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Dirt Dobber - 2018-05-14 6:03 PM It appears I have done my homework and my vet has advised me well. 

I am guessing the videos and articles are posted by those who had bad experiences with osphos.  I hope your horses are doing better.

 No I haven’t had a bad experience with Osphos and neither has Herbie, that I know of.

It was prescribed for my mare who got hurt last fall and ended up with a rare form of arthritis in her upper hock. The specialist I took her to said it was my only chance to run her again. I went home and did my homework because I have learned a thousand times over now that vets don’t know it all. No human does. I wanted to know what actually goes on inside the body when bisphosphonates (Osphos/Tildren) are given. I was curious why they were no longer used in humans. After my homework was done I made the decision not to go forward with Osphos. The long term unknowns scare me and the known effects of increased bone fragility and fetal abnormalities seen when given to broodmares, terrified me... If Osphos wouldn’t have worked my mares only option left would be to raise some babies. So for my situation I choose to retire her and lease her out on a broodmare lease. If I would have given her Osphos maybe I would have gotten another year with her, then what? She is going to make some fantastic babies and even though I miss running her, I am beyond thankful I made the decision I did.

I posted the video because I want people to inform themselves. Taking what you hear or what you are told to heart may get you into a situation you don’t want to be in. 

If Osphos has helped anyone’s horse, that’s great. Best of luck to everyone who is trying to navigate this crazy world of horses. They put us all through the wringer, that’s for sure. 

 
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Dirt Dobber
Reg. Jun 2009
Posted 2018-05-15 5:10 AM
Subject: RE: Osphos


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MidWest1452 - 2018-05-14 9:40 PM
Dirt Dobber - 2018-05-14 6:03 PM It appears I have done my homework and my vet has advised me well. 

I am guessing the videos and articles are posted by those who had bad experiences with osphos.  I hope your horses are doing better.
 No I haven’t had a bad experience with Osphos and neither has Herbie, that I know of.



It was prescribed for my mare who got hurt last fall and ended up with a rare form of arthritis in her upper hock. The specialist I took her to said it was my only chance to run her again. I went home and did my homework because I have learned a thousand times over now that vets don’t know it all. No human does. I wanted to know what actually goes on inside the body when bisphosphonates (Osphos/Tildren) are given. I was curious why they were no longer used in humans. After my homework was done I made the decision not to go forward with Osphos. The long term unknowns scare me and the known effects of increased bone fragility and fetal abnormalities seen when given to broodmares, terrified me... If Osphos wouldn’t have worked my mares only option left would be to raise some babies. So for my situation I choose to retire her and lease her out on a broodmare lease. If I would have given her Osphos maybe I would have gotten another year with her, then what? She is going to make some fantastic babies and even though I miss running her, I am beyond thankful I made the decision I did.



I posted the video because I want people to inform themselves. Taking what you hear or what you are told to heart may get you into a situation you don’t want to be in. 



If Osphos has helped anyone’s horse, that’s great. Best of luck to everyone who is trying to navigate this crazy world of horses. They put us all through the wringer, that’s for sure. 


 

So it was being prescribed off label for your horse which Dr. Bramlage has a huge issue with.  My vet talked about this as well.  My horse is well with in the manufacturers label recommendation, age and treatment.  I've have the best vet ever!
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MidWest1452
Reg. May 2013
Posted 2018-05-15 8:22 AM
Subject: RE: Osphos



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Posts: 595
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Dirt Dobber - 2018-05-15 5:10 AM
MidWest1452 - 2018-05-14 9:40 PM
Dirt Dobber - 2018-05-14 6:03 PM It appears I have done my homework and my vet has advised me well. 

I am guessing the videos and articles are posted by those who had bad experiences with osphos.  I hope your horses are doing better.
 No I haven’t had a bad experience with Osphos and neither has Herbie, that I know of.



It was prescribed for my mare who got hurt last fall and ended up with a rare form of arthritis in her upper hock. The specialist I took her to said it was my only chance to run her again. I went home and did my homework because I have learned a thousand times over now that vets don’t know it all. No human does. I wanted to know what actually goes on inside the body when bisphosphonates (Osphos/Tildren) are given. I was curious why they were no longer used in humans. After my homework was done I made the decision not to go forward with Osphos. The long term unknowns scare me and the known effects of increased bone fragility and fetal abnormalities seen when given to broodmares, terrified me... If Osphos wouldn’t have worked my mares only option left would be to raise some babies. So for my situation I choose to retire her and lease her out on a broodmare lease. If I would have given her Osphos maybe I would have gotten another year with her, then what? She is going to make some fantastic babies and even though I miss running her, I am beyond thankful I made the decision I did.



I posted the video because I want people to inform themselves. Taking what you hear or what you are told to heart may get you into a situation you don’t want to be in. 



If Osphos has helped anyone’s horse, that’s great. Best of luck to everyone who is trying to navigate this crazy world of horses. They put us all through the wringer, that’s for sure. 


 
So it was being prescribed off label for your horse which Dr. Bramlage has a huge issue with.  My vet talked about this as well.  My horse is well with in the manufacturers label recommendation, age and treatment.  I've have the best vet ever!

I see your point about off label use but what it does inside the body is the same no matter where the issue lies. Osteoclasts activity is decreased and that isn’t restricted to the site of the problem and the rate as to which the bisphosphonates are released from the bone is between months to years depending on the horse. That’s years that the horses normal bone activity is changed. Normal bone activity that is needed to repair tiny microscopic damage that happens on an everyday basis. I could go on and on but I won’t because that would be even more obnoxious of me. Haha I’m glad you and your vet discussed all of the information.
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cindyt
Reg. Dec 2003
Posted 2018-05-15 8:34 AM
Subject: RE: Osphos


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It was a waste of money for me...
 
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CJE
Reg. Mar 2005
Posted 2018-05-15 9:42 AM
Subject: RE: Osphos



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MidWest1452 - 2018-05-12 1:23 PM

 A video worth watching if considering Osphos. If you have looked up past threads then I won't state my opinion again on them. 

Video Link:

https://vimeo.com/257695901

Wow that was interesting..............
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CJE
Reg. Mar 2005
Posted 2018-05-15 9:50 AM
Subject: RE: Osphos



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Any success with horses that are showing signs of navicular changes and lameness with osphos?
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BIGMAMMATOO
Reg. Aug 2005
Posted 2018-05-16 12:00 AM
Subject: RE: Osphos



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My daughter's mare has navicular.  We have given 3 doses, 6 months apart over the last year and a half.  We were having to inject her front feet every 6-8 weeks to keep her comfortable.  She has not been injected in over a year.  In the last 2 months, she has won 5 of the 6 rodeos she was entered in. The rodeo last weekend, she had the fastest time of the whole rodeo.  (She is in the 8 under, It was the AJRA in Sweetwater, Texas that has age groups up to 19 yrs old).  I would say that it has saved this mare.  I read the article that was posted, and that is regarding the use on the track in young horses to mask injury, because they can't detect the drug in drug tests.  In my case, it was given for navicular, and it has saved our mare.  The reason that you don't give the drug while on Previcox, bute or banamine, is because it is hard on the kidneys and that compounds the problem.  I ran a BUN and Crea (Blood test which moniters Kidney function) before I give a dose and 5 days after.  
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Dirt Dobber
Reg. Jun 2009
Posted 2018-05-16 4:46 AM
Subject: RE: Osphos


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CJE - 2018-05-15 9:50 AM Any success with horses that are showing signs of navicular changes and lameness with osphos?
My horse.  He has been completely sound on the left front 6 weeks after the injection and was sound on the right front until March.  He has a cyst and when we changed up the paddinig material on his shoeing we think it irritated the cyst.  The cyst has not made any changes which is good because it hasn't grown.  My horse wasn't even pasture sound until the injection.  He was a train wreck and after the injection he became comfortable with his entire body because he wasn't trying to carry his weight all in his rear end.  After the second injection the other day he is at least pasture sound on the right front again. 
Forgot to add since the first injection there haven't been any more changes to the navicular or coffin bone.  He has a spur to on the coffin bone.  So right now everything looks stable.


Edited by Dirt Dobber 2018-05-16 4:49 AM
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CJE
Reg. Mar 2005
Posted 2018-05-16 5:15 PM
Subject: RE: Osphos



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Dirt Dobber - 2018-05-15 5:46 AM

CJE - 2018-05-15 9:50 AM Any success with horses that are showing signs of navicular changes and lameness with osphos?
My horse.  He has been completely sound on the left front 6 weeks after the injection and was sound on the right front until March.  He has a cyst and when we changed up the paddinig material on his shoeing we think it irritated the cyst.  The cyst has not made any changes which is good because it hasn't grown.  My horse wasn't even pasture sound until the injection.  He was a train wreck and after the injection he became comfortable with his entire body because he wasn't trying to carry his weight all in his rear end.  After the second injection the other day he is at least pasture sound on the right front again. 
Forgot to add since the first injection there haven't been any more changes to the navicular or coffin bone.  He has a spur to on the coffin bone.  So right now everything looks stable.

Just got back from the vet today....we had injected her bursa's and not the improvement I've seen in the past with them.....so I took her back for x-rays today and showed 2 cysts......vet had already suggested to the Osphous but I don't like doing two things at once.......I want to know what works.........and what we were up against......now to decide it I want to go through with this or broodmare.....

Edited by CJE 2018-05-16 5:21 PM
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Herbie
Reg. Oct 2003
Posted 2018-05-17 11:44 AM
Subject: RE: Osphos


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CJE - 2018-05-16 5:15 PM
Dirt Dobber - 2018-05-15 5:46 AM
CJE - 2018-05-15 9:50 AM Any success with horses that are showing signs of navicular changes and lameness with osphos?
My horse.  He has been completely sound on the left front 6 weeks after the injection and was sound on the right front until March.  He has a cyst and when we changed up the paddinig material on his shoeing we think it irritated the cyst.  The cyst has not made any changes which is good because it hasn't grown.  My horse wasn't even pasture sound until the injection.  He was a train wreck and after the injection he became comfortable with his entire body because he wasn't trying to carry his weight all in his rear end.  After the second injection the other day he is at least pasture sound on the right front again. 

Forgot to add since the first injection there haven't been any more changes to the navicular or coffin bone.  He has a spur to on the coffin bone.  So right now everything looks stable.
Just got back from the vet today....we had injected her bursa's and not the improvement I've seen in the past with them.....so I took her back for x-rays today and showed 2 cysts......vet had already suggested to the Osphous but I don't like doing two things at once.......I want to know what works.........and what we were up against......now to decide it I want to go through with this or broodmare.....

My question would be how, specifically, will the use of a biophosphonate affect a cyst?  How are the soft tissues affected by that cyst?   
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CJE
Reg. Mar 2005
Posted 2018-05-17 5:36 PM
Subject: RE: Osphos



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Herbie - 2018-05-16 12:44 PM

CJE - 2018-05-16 5:15 PM
Dirt Dobber - 2018-05-15 5:46 AM
CJE - 2018-05-15 9:50 AM Any success with horses that are showing signs of navicular changes and lameness with osphos?
My horse.  He has been completely sound on the left front 6 weeks after the injection and was sound on the right front until March.  He has a cyst and when we changed up the paddinig material on his shoeing we think it irritated the cyst.  The cyst has not made any changes which is good because it hasn't grown.  My horse wasn't even pasture sound until the injection.  He was a train wreck and after the injection he became comfortable with his entire body because he wasn't trying to carry his weight all in his rear end.  After the second injection the other day he is at least pasture sound on the right front again. 

Forgot to add since the first injection there haven't been any more changes to the navicular or coffin bone.  He has a spur to on the coffin bone.  So right now everything looks stable.
Just got back from the vet today....we had injected her bursa's and not the improvement I've seen in the past with them.....so I took her back for x-rays today and showed 2 cysts......vet had already suggested to the Osphous but I don't like doing two things at once.......I want to know what works.........and what we were up against......now to decide it I want to go through with this or broodmare.....

My question would be how, specifically, will the use of a biophosphonate affect a cyst?  How are the soft tissues affected by that cyst?   

My vet thinks there the results will be positive........I am a doubter........and I know he said no to nerving........the results of that could be catastrophic was the impression I got.....
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Chandler's Mom
Reg. Jan 2015
Posted 2018-05-17 8:15 PM
Subject: RE: Osphos



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CJE - 2018-05-17 5:36 PM

Herbie - 2018-05-16 12:44 PM

CJE - 2018-05-16 5:15 PM
Dirt Dobber - 2018-05-15 5:46 AM
CJE - 2018-05-15 9:50 AM Any success with horses that are showing signs of navicular changes and lameness with osphos?
My horse.  He has been completely sound on the left front 6 weeks after the injection and was sound on the right front until March.  He has a cyst and when we changed up the paddinig material on his shoeing we think it irritated the cyst.  The cyst has not made any changes which is good because it hasn't grown.  My horse wasn't even pasture sound until the injection.  He was a train wreck and after the injection he became comfortable with his entire body because he wasn't trying to carry his weight all in his rear end.  After the second injection the other day he is at least pasture sound on the right front again. 

Forgot to add since the first injection there haven't been any more changes to the navicular or coffin bone.  He has a spur to on the coffin bone.  So right now everything looks stable.
Just got back from the vet today....we had injected her bursa's and not the improvement I've seen in the past with them.....so I took her back for x-rays today and showed 2 cysts......vet had already suggested to the Osphous but I don't like doing two things at once.......I want to know what works.........and what we were up against......now to decide it I want to go through with this or broodmare.....

My question would be how, specifically, will the use of a biophosphonate affect a cyst?  How are the soft tissues affected by that cyst?   

My vet thinks there the results will be positive........I am a doubter........and I know he said no to nerving........the results of that could be catastrophic was the impression I got.....

I just saw your other post---may she produce beautiful and talented babies for you. . . .
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