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Update! Kate has EPM! Experiences with Marquis?!?!

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lexyy12
Reg. Apr 2010
Posted 2014-12-12 11:47 AM
Subject: Update! Kate has EPM! Experiences with Marquis?!?!



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Location: ohio-in my own little world with pretty ponies :)
 Last week I got Kate into the vet to have her checked out. Knew she was sore in her hind end but not showing lameness and then completely lost her back legs at the first and went down. X-ray everything. Did a lameness exam. X Rays came back good. Took blood and sent it in for a few tests. 


Got got the call this morning that he was right...she has EPM. Obviously we are going to be starting treatment ASAP. He wants to use Marquis to treat it. From what I understand it's a one month treatment and she gets 1 tube a week. Where is the best place to buy this? The cheapest I can find is $749 for the whole treatment. Any suggestions?


Edited by lexyy12 2014-12-12 1:11 PM
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quikchik
Reg. Jun 2007
Posted 2014-12-12 12:16 PM
Subject: RE: Update! Kate went to the vet


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Maybe add EPM to the title. I know a lot of people have posted experiences with treatments, it might catch their eye.
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FLITASTIC
Reg. Jun 2012
Posted 2014-12-12 12:27 PM
Subject: RE: Update! Kate went to the vet



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I have always had good luck with valleyvet.com or allivet.com for meds. Both ship very fast.
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FlyingJT
Reg. Jan 2014
Posted 2014-12-12 12:55 PM
Subject: RE: Update! Kate went to the vet



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From experience, I will never use marquis again!!! I would look into Orogin or Diclazril. Cheaper and work faster and better, in my opinion!
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hoofs_in_motion
Reg. Apr 2011
Posted 2014-12-12 1:12 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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I have no advise but prayers, I do belive I saw your facebook post.  
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BettyBarrelRacer
Reg. Dec 2003
Posted 2014-12-12 1:21 PM
Subject: RE: Update! Kate went to the vet



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FlyingJT - 2014-12-12 12:55 PM From experience, I will never use marquis again!!! I would look into Orogin or Diclazril. Cheaper and work faster and better, in my opinion!

I treated twice with marquis and had little success. Just my experience. 
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casualdust07
Reg. Mar 2005
Posted 2014-12-12 1:42 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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I treated with oroquin and did not have success. Treated a second time with Marquis and cleared it.


Diclazuril is an off label option for EPM, but its a good choice and if your horse didnt respond to Marquis I would try it.

Marquis is expensive and there's no way around the cost.

Honestly, EPM is a hard infection to clear, so I'm not surprised to see horses not respond to one drug and respond to another, or require multiple rounds of treatments to clear it.

Nitazoxanide is another drug that is approved to treat EPM in horses, I believe it's called Navigator but I personally haven't heard of it until taking pharmacology in vet school... and the prof giving the lecture was a small animal vet so for all I know it may not even be available.
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LoneStar
Reg. May 2004
Posted 2014-12-12 1:44 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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I had good luck with the Marquis... 
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Jenbabe
Reg. Jul 2006
Posted 2014-12-12 1:45 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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We were prescribed IV Diclazuril followed by sulfa meds.
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rachellyn80
Reg. Jan 2004
Posted 2014-12-12 2:17 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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I just treated with Orogin from Pathogenes in Florida and have seen great results....and this was on a 27 year old mare.  Orogin is $200 and you treat for 10 days.

I've never treated with Marquis due to the stories that I've heard about relapse and it just not working as well as anything else....and it's much more expensive. 
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bluerose2001
Reg. Mar 2009
Posted 2014-12-12 2:19 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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Well I have Marquis and Rebalance I no longer need. Lost my boy to the injury that made us find the EPM. The EPM was getting better and improvements being made in that area. The severed nerve from the injury resulted in his death. I would love to get that medicine out of my sight and put some money toward getting a young horse broke. It is honestly very depressing to have in the house.
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FlyingJT
Reg. Jan 2014
Posted 2014-12-12 2:26 PM
Subject: RE: Update! Kate went to the vet



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BettyBarrelRacer - 2014-12-12 1:21 PM

FlyingJT - 2014-12-12 12:55 PM From experience, I will never use marquis again!!! I would look into Orogin or Diclazril. Cheaper and work faster and better, in my opinion!

I treated twice with marquis and had little success. Just my experience. 

Same here!! never again!
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lexyy12
Reg. Apr 2010
Posted 2014-12-12 9:36 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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 I was able to find it at least a little cheaper at $749 for the whole treatment  My whole fear is spending all of this money and her not getting better. I guess no matter what there is never a guarantee. My vet strongly advises this for her case. 

I have a question though...is this something worth getting a second opinion on? Can the test be wrong? Could he read it wrong? I know nothing about this except it needs treated ASAP!

Im afraid to try something else cheaper and it not work and her get worse and then have to go through with this anyway. Im very upset about this news..I really thought we were just going to get an injection and be over with. This mare means a lot to me...Ive put so much blood, sweat, tears and love into her. gaaahhhh....the life of owning horses. Perfect timing with Christmas and all...
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lexyy12
Reg. Apr 2010
Posted 2014-12-12 9:37 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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bluerose2001 - 2014-12-12 3:19 PM Well I have Marquis and Rebalance I no longer need. Lost my boy to the injury that made us find the EPM. The EPM was getting better and improvements being made in that area. The severed nerve from the injury resulted in his death. I would love to get that medicine out of my sight and put some money toward getting a young horse broke. It is honestly very depressing to have in the house.

 sent you a pm!!
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kipper
Reg. Jan 2005
Posted 2014-12-12 9:59 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!


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 Same yourself time and money and treat with Origin. 
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RunNbarrels
Reg. Nov 2008
Posted 2014-12-12 11:33 PM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!


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 I treated my mare with Origin this summer and she is doing great. I'd treat another with it again without hesitation. 
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OhMax
Reg. Feb 2013
Posted 2014-12-13 10:42 AM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!


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We used toltrazuril on a total of 4 that I know personally this summer, including mine, and had great results on all. 2 treatments, our vet priced around $500 and started seeing the horses come back quite quickly, with one hitting a paycheck at a rodeo a week later.
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lexyy12
Reg. Apr 2010
Posted 2014-12-15 10:31 AM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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Location: ohio-in my own little world with pretty ponies :)
 Got the marquis ordered this morning. Should be here tomorrow or the next day. Praying this helps my girl!
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streakysox
Reg. Jul 2008
Posted 2014-12-15 11:03 AM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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casualdust07 - 2014-12-12 1:42 PM

I treated with oroquin and did not have success. Treated a second time with Marquis and cleared it.


Diclazuril is an off label option for EPM, but its a good choice and if your horse didnt respond to Marquis I would try it.

Marquis is expensive and there's no way around the cost.

Honestly, EPM is a hard infection to clear, so I'm not surprised to see horses not respond to one drug and respond to another, or require multiple rounds of treatments to clear it.

Nitazoxanide is another drug that is approved to treat EPM in horses, I believe it's called Navigator but I personally haven't heard of it until taking pharmacology in vet school... and the prof giving the lecture was a small animal vet so for all I know it may not even be available.

According to my vet. Navigator has been taken off the market. I have used tow different drugs. One is Rebalance (pyrimethamine) and Baycox (toltrazuril) I have had good success with both. My vet put my horse on a preventative program and he will probably have to have it the rest of his life. Neither of these treatments are excessively expensive.
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dianeguinn
Reg. Oct 2003
Posted 2014-12-15 11:16 AM
Subject: RE: Update! Kate has EPM! Experiences with Marquis?!?!



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lexyy12 - 2014-12-12 9:36 PM

 I was able to find it at least a little cheaper at $749 for the whole treatment  My whole fear is spending all of this money and her not getting better. I guess no matter what there is never a guarantee. My vet strongly advises this for her case. 

I have a question though...is this something worth getting a second opinion on? Can the test be wrong? Could he read it wrong? I know nothing about this except it needs treated ASAP!

Im afraid to try something else cheaper and it not work and her get worse and then have to go through with this anyway. Im very upset about this news..I really thought we were just going to get an injection and be over with. This mare means a lot to me...Ive put so much blood, sweat, tears and love into her. gaaahhhh....the life of owning horses. Perfect timing with Christmas and all...

Any test on animals or humans can be wrong, and a second opinion is always a good idea. Sounds like your vet is way behind the times on EPM research. Marquis was the first treatment that was widely used for EPM, and it's not very effective. In fact, I think the protozoa has become immune to it, just like worms become immune to wormer, and that's why it doesn't work well. I would agree with what everyone else said on here....the cheaper treatments are actually better if they're the Diclazuril or Orogin 10. Sometimes it takes several treatments to get rid of it, as some treatments will just cut the number down (once again, similar to worms....it IS a parasite....but is a protozoa, not a worm and it attacks the nervous system which is much more dangerous), but not clear the infection. Most of the time horses will need a couple of treatments before it's gone. I've had the best luck with the Orogin 10 (pill given for 10 days) followed by Levamisole for 14 days. That total treatment will not cost you as much as one tube of Marquis. ;)
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