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NFR2EQUINE
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Chandler's Mom
Reg. Jan 2015
Posted 2018-11-22 8:52 PM (#7414151 - in reply to #7414143)
Subject: RE: NFR2EQUINE



My Heart Be Happy


Posts: 6888
50001000500100100100252525
Location: Arkansas
run n rate - 2018-11-22 7:24 PM

Chandler's Mom - 2018-11-22 3:15 PM

run n rate - 2018-11-21 12:18 PM

I started taking the product @ 2 years ago for myself. I had stressed fractured 3 vertebrae 9 or 10 years ago at a clinic. My back had gotten to the point I had to give up running and working out as the pain in my lower back and hips was mind numbing. I had gotten to the point that if I could manage to ride 3 of my horses in a day the next day I was so sore I was pretty well couch bound, my left leg would go numb in left hand circles. In a run I was usually worried about staying on rather than how I was riding.
A former gymnast I had had many years ago talked me into trying it like I said about 2 years ago. It was a miracle drug over night success. First thing I noticed was I had more energy at the end of a long day, not nervous sick to my stomach energy drink type energy. Just had some more get up and lets do this, didn't have to guilt myself into getting a quick ride in on my horses at the end of a work day. Then a month or so in Dave was no longer having to help me sit up in bed first thing in the morning. A year in I was back to being able to ride all 3 horses and be able to move the next day and even get all 3 ridden both days on the weekend. Last February, about a year and half of the Nrf2 I was able to go back to the gym again for the first time in 4 years or so and was even able to start some light running again as well as go home and get a horse or 2 ridden depending on the amount of sunlight I had. This summer I loaded and unloaded a ton of hay by myself and then still got all the horses ridden and was able to ride again the next day. I'm 53, I no longer live on Ibuprofen and Aleve and I can actually enjoy my horses again. And yes, recently I started my horses on the product also so we will see how they do on it. I can only speak of my results personally in regards to my back as of yet.

Mercy this sounds like something I would like Sean to try for his back. . . . Definitely gonna look into this more. So glad it's made a difference for you RNR as well as some of the others

About a month or more after I first started it I lost my debit card and had to cancel my card which negated my auto ship of NRF2. It was kind of a pain in the butt to get signed up so i thought “it didn’t make that much of a difference really, I’m just going to forget it”. A week later Dave was having to sit me up in bed again. Funny how quickly when you feel better that you forget how bad things were “before”. The longer I’ve been on the product the more results I’ve gotten. On top on the added bit of energy and my back feeling much better, I haven’t had the migraine issues like before either.

I do believe I'm gonna get him to try this. Between you and Steph and some of the others, I'm convinced it's worth it.
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getacheck
Reg. Jan 2004
Posted 2018-11-23 12:01 AM (#7414161 - in reply to #7413957)
Subject: RE: NFR2EQUINE


Elite Veteran


Posts: 1011
1000
Location: TX
I see a lot of dealers/distributors posting results. I would like to see information from actual people using the product on their horses and nothing personal, but horses that have actually been to a vet with documentation of their lameness and persons competing. Very vague on what it is supposed to actually do, except make a lame navicular horse sound and able to run again.
Please post factual information, a lot of people in the industry could benefit.


Edited by getacheck 2018-11-23 12:21 AM
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ropenrun
Reg. Nov 2004
Posted 2018-11-25 11:15 AM (#7414305 - in reply to #7414161)
Subject: RE: NFR2EQUINE




10002525
Location: In my own little world
getacheck - 2018-11-22 11:01 PM

I see a lot of dealers/distributors posting results. I would like to see information from actual people using the product on their horses and nothing personal, but horses that have actually been to a vet with documentation of their lameness and persons competing. Very vague on what it is supposed to actually do, except make a lame navicular horse sound and able to run again.
Please post factual information, a lot of people in the industry could benefit.

I would say a good portion of the dealers used the product and saw great results or they would not be selling it. I don't sell this product nor have I used it to date, but for products I personally sell, I wouldn't be selling them if I didn't believe they work. And just like many products both human and horse, herbal or pharma, what works for one does not always work for the next. Everyone needs to see for themselves. It is not an overly expensive item to take a gamble on. If it works, then you scored big time.
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CYA Ranch
Reg. Feb 2008
Posted 2018-11-25 11:23 AM (#7414307 - in reply to #7413957)
Subject: RE: NFR2EQUINE


Military family

More bootie than waist!


Posts: 18406
50005000500020001000100100100100
Location: Riding Crackhead.
How much Protandum are you feeding daily?  My co-worker is a distributor and she's been trying to get me to try it for the past 3 years.  I need feedback from other horse owners before I spend the money.

 
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1DSoon
Reg. May 2009
Posted 2018-11-26 7:01 AM (#7414377 - in reply to #7414305)
Subject: RE: NFR2EQUINE





1000500100100
Location: Not Where I Want to Be
ropenrun - 2018-11-25 12:15 PM
getacheck - 2018-11-22 11:01 PM I see a lot of dealers/distributors posting results. I would like to see information from actual people using the product on their horses and nothing personal, but horses that have actually been to a vet with documentation of their lameness and persons competing. Very vague on what it is supposed to actually do, except make a lame navicular horse sound and able to run again. Please post factual information, a lot of people in the industry could benefit.
I would say a good portion of the dealers used the product and saw great results or they would not be selling it. I don't sell this product nor have I used it to date, but for products I personally sell, I wouldn't be selling them if I didn't believe they work. And just like many products both human and horse, herbal or pharma, what works for one does not always work for the next. Everyone needs to see for themselves. It is not an overly expensive item to take a gamble on. If it works, then you scored big time.

You just gave a text book anecdotal description of Thrive and a 100 MLM schemes 


 
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ropenrun
Reg. Nov 2004
Posted 2018-11-26 9:36 PM (#7414502 - in reply to #7414377)
Subject: RE: NFR2EQUINE




10002525
Location: In my own little world
1DSoon - 2018-11-26 6:01 AM
ropenrun - 2018-11-25 12:15 PM
getacheck - 2018-11-22 11:01 PM I see a lot of dealers/distributors posting results. I would like to see information from actual people using the product on their horses and nothing personal, but horses that have actually been to a vet with documentation of their lameness and persons competing. Very vague on what it is supposed to actually do, except make a lame navicular horse sound and able to run again. Please post factual information, a lot of people in the industry could benefit.
I would say a good portion of the dealers used the product and saw great results or they would not be selling it. I don't sell this product nor have I used it to date, but for products I personally sell, I wouldn't be selling them if I didn't believe they work. And just like many products both human and horse, herbal or pharma, what works for one does not always work for the next. Everyone needs to see for themselves. It is not an overly expensive item to take a gamble on. If it works, then you scored big time.
You just gave a text book anecdotal description of Thrive and a 100 MLM schemes 





 

And I've never been involved in any MLM product sales in my life so not all books read the same.  I've never used this product either.  But I'm about too give it a try because so far no vets have been able to provide an answer or relief.   $40 to try this is much less expensive  than yet another $75 vet office visit with no solution.  It's worth the gamble for me.
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ropenrun
Reg. Nov 2004
Posted 2018-11-26 9:39 PM (#7414503 - in reply to #7414307)
Subject: RE: NFR2EQUINE




10002525
Location: In my own little world
CYA Ranch - 2018-11-25 10:23 AM How much Protandum are you feeding daily?  My co-worker is a distributor and she's been trying to get me to try it for the past 3 years.  I need feedback from other horse owners before I spend the money.



 

CYA I was told 1 pill a day but you can do a loading dose of  1 in the AM and 1 in the PM for 10 days to jumpstart it. 
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CYA Ranch
Reg. Feb 2008
Posted 2018-11-27 10:19 AM (#7414538 - in reply to #7414503)
Subject: RE: NFR2EQUINE


Military family

More bootie than waist!


Posts: 18406
50005000500020001000100100100100
Location: Riding Crackhead.
ropenrun - 2018-11-26 9:39 PM
CYA Ranch - 2018-11-25 10:23 AM How much Protandum are you feeding daily?  My co-worker is a distributor and she's been trying to get me to try it for the past 3 years.  I need feedback from other horse owners before I spend the money.



 
CYA I was told 1 pill a day but you can do a loading dose of  1 in the AM and 1 in the PM for 10 days to jumpstart it. 

So basically the same as human dose?

 
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Lovin Life
Reg. Apr 2004
Posted 2018-11-27 1:45 PM (#7414572 - in reply to #7413957)
Subject: RE: NFR2EQUINE



Vodka for Lunch


100010010010025
Location: Lala Land
I'm not trying to be a hater, but some of the "miracle" videos I could get the same result from a dose of bute. I haven't had one person selling that could actually explain why/how it works with scientific backup. Especially with the MLM involved it just seems too good to be true that one pill can cure everything that ails you and your horse.

Edited by Lovin Life 2018-11-27 1:47 PM
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2H~QH
Reg. Jul 2014
Posted 2018-11-27 2:03 PM (#7414574 - in reply to #7413957)
Subject: RE: NFR2EQUINE



Veteran


Posts: 239
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I tried the human version....NRF2 synergizer/protandim/"LYP" for the recommended 3 months and saw no changes in my aches pains energy level etc. At 72$ CDN per month for me, I could not justify continuing to purchase it nor could I justify the price for trying it on a horse.
There are some peer-reviewed articles out there yes, but the one I actually read could not determine if there was an actual statistically significant relationship between administering of the product to male mice and a decrease in mitochondrial oxidative damage. 
At the end of the day it's still a MLM selling scheme and that drives the price to the consumer up, most of the sellers will post links to the pubmed articles but you cannot actually access the article (you can only read the abstract).

 
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Lovin Life
Reg. Apr 2004
Posted 2018-11-27 2:06 PM (#7414576 - in reply to #7414574)
Subject: RE: NFR2EQUINE



Vodka for Lunch


100010010010025
Location: Lala Land
I read an article that compared it to snake oil. lol
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SwiftSmokinLady
Reg. Oct 2006
Posted 2018-11-27 2:22 PM (#7414577 - in reply to #7413957)
Subject: RE: NFR2EQUINE



Elite Veteran


Posts: 1116
1000100
If you look at the ingredients list I have seen, along with some other herbs, the main ingredient is turmeric.
You can get it cheaper and feed alone, and get basically the same results I think.

...this coming from someone who was very close to buying, but spent lots of time researching.
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GLP
Reg. Oct 2013
Posted 2018-11-27 2:30 PM (#7414578 - in reply to #7414572)
Subject: RE: NFR2EQUINE


I just read the headlines


Posts: 3885
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Lovin Life - 2018-11-27 1:45 PM

I'm not trying to be a hater, but some of the "miracle" videos I could get the same result from a dose of bute. I haven't had one person selling that could actually explain why/how it works with scientific backup. Especially with the MLM involved it just seems too good to be true that one pill can cure everything that ails you and your horse.

That’s true, but with bute you are looking at ulcers developing quickly, so if you get the same results, why not use something that doesn’t have ulcers as a common side effect? I did use Protandem for several months on my horse when he scratched his eye on a mesquite thorn. Vet said he would likely lose the eye because of the massive infection. This happened over night which is common with mesquite thorns- nasty business they are. Anyway, the vet said it was imperative that he develop new capillaries in his eye to help with the healing. I gave Protandem and the vet was freaking out about how many developed, and felt that was a major reason he not only kept his eye, but has some vision in it too. The vet also said we needed to try to keep the lavage in for hopefully 6 weeks but longer if we could. A lot of horses itch it out, but Jim kept it for 12 weeks again a major contribution to his healing. I believe the Protandem helped with his attitude, I never gave him ace or anything else to keep him calm for 12 weeks of complete stall time. Anyway that is my experience.
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lindseylou2290
Reg. Aug 2013
Posted 2018-11-27 2:35 PM (#7414581 - in reply to #7413957)
Subject: RE: NFR2EQUINE



Expert


Posts: 2436
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NRF2 is an actual cellular pathway that scientists have been exploring for potential therapeutic uses. - wiki link that explains this easily for the layman - https://en.wikipedia.org/wiki/NFE2L2

HOWEVER - here's the kicker, that pathway is vital to some cell functions and not always a smart move to suppress, depending on what you are trying to treat.
link to peer reviewed article citing a really good overview of this pathway fits into disease - https://www.sciencedirect.com/science/article/pii/S0925443916302861

Also worthy of note, oxidative stress is a normal cell function. But an OVER abundance of it can cause more damage in an already compromised situation.
link to a good peer review article on this topic and how the NRF2 pathway is involved - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680839/

Lastly - there is one FDA approved drug on the market TECFIDERA (dimethyl fumarate) to treat Multiple Sclerosis by exploiting this pathway; it can reduce relapse episodes. HOWEVER - this drug has some pretty major side effects, including anaphalaxis and liver damage.

Oltipraz is another NRF2 pathway drug that showed some early signs of inhibiting cancer in certain organs - however, it never went past rodent trials as it created super radicals which can become toxic. - link to peer reviewed article about some of the early cancer research done with it (1993) - https://www.ncbi.nlm.nih.gov/pubmed/8412206

Personally, I wouldn't touch the NRF2 drugs that are out there as there is no scientific consensus between the current research available. I wouldn't take "the jesus shot" and I certainly wouldn't be using these products off label. I like my liver and I don't have MS.

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cindyt
Reg. Dec 2003
Posted 2019-01-09 11:48 AM (#7418505 - in reply to #7414305)
Subject: RE: NFR2EQUINE


Ms Bling Bling Sleeze Kitty


Posts: 20393
5000500050005000100100100252525
Location: LouLouVille, OK
ropenrun - 2018-11-25 11:15 AM
getacheck - 2018-11-22 11:01 PM I see a lot of dealers/distributors posting results. I would like to see information from actual people using the product on their horses and nothing personal, but horses that have actually been to a vet with documentation of their lameness and persons competing. Very vague on what it is supposed to actually do, except make a lame navicular horse sound and able to run again. Please post factual information, a lot of people in the industry could benefit.
I would say a good portion of the dealers used the product and saw great results or they would not be selling it. I don't sell this product nor have I used it to date, but for products I personally sell, I wouldn't be selling them if I didn't believe they work. And just like many products both human and horse, herbal or pharma, what works for one does not always work for the next. Everyone needs to see for themselves. It is not an overly expensive item to take a gamble on. If it works, then you scored big time.

Im with getacheck...  I mean I understand people becoming a dealer of something that worked for them, but I see very few if at all any that actually promote it without selling it... Anyone?
 
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zansbeunogal_2268
Reg. Dec 2009
Posted 2019-01-09 11:59 AM (#7418506 - in reply to #7413957)
Subject: RE: NFR2EQUINE


Extreme Veteran


Posts: 367
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this may be a dumb question, but does it compare to curost total equine???

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SKM
Reg. Dec 2003
Posted 2019-01-09 1:42 PM (#7418518 - in reply to #7414307)
Subject: RE: NFR2EQUINE



Saint Stacey


500050005000500050005000500050025
CYA Ranch - 2018-11-25 10:23 AM

How much Protandum are you feeding daily?  My co-worker is a distributor and she's been trying to get me to try it for the past 3 years.  I need feedback from other horse owners before I spend the money.

 

I was told loading dose of 2 pills for 30 days, then 1 pill daily after that. I was also told to give is with fat as it’s fat soluble so it’s easier to absorb if given with some kind of fat.
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Liana D
Reg. Sep 2008
Posted 2019-01-09 2:44 PM (#7418526 - in reply to #7413957)
Subject: RE: NFR2EQUINE


Defense Attorney for The Horse


500100252525
Location: Claremore, OK
I do my best to post only positive things but I’ve got to say I think it’s the biggest bunch of BS I’ve seen in a long time. At one time they claimed to be the “fountain of youth pill”, until they were sued.

I can keep an apple from turning brown by pouring 7up on it. Does 7up reduce. “Oxidative stress “ ?
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1DSoon
Reg. May 2009
Posted 2019-01-09 2:50 PM (#7418527 - in reply to #7418506)
Subject: RE: NFR2EQUINE





1000500100100
Location: Not Where I Want to Be
zansbeunogal_2268 - 2019-01-09 12:59 PM this may be a dumb question, but does it compare to curost total equine???

 yes they are exactly the same in the respect that neither of them work. 


Biggest diff is the Cur-ost insn't a MLM scheme like NFR stuff


 
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KKCOWGIRL
Reg. Aug 2010
Posted 2019-01-09 2:51 PM (#7418528 - in reply to #7413957)
Subject: RE: NFR2EQUINE


SHOOT IT


Posts: 1159
10001002525
Location: TEXAS
I don't know if the product is good or bad, all I can go by is my personal experience.  I tried it for myself AND I gave it to one of my horses for about 3 months.  No changes were seen with my horse and I certainly didn't feel any better.  My husband took it to his doctor and the doctor looked at the label and rolled his eyes and asked what we paid for it.  And for those reasons, I quit taking it. 
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