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Human omeprazole used on a horse?


svincent Reg. Feb 2012	Posted 2014-05-29 10:09 AM Subject: Human omeprazole used on a horse?
The Resident Destroyer of Liberal Logic Location: PNW	The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!!
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Douglas J Gordon Reg. Jun 2008	Posted 2014-05-29 10:12 AM Subject: RE: Human omeprazole used on a horse?
BHW's Lance Armstrong Posts: 11134 Location: Somewhere between S@%&# stirrer and Saint	svincent - 2014-05-29 10:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! You would have to use about 120 of those pills per day for a month to cure ulcers.
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WalknFaith Reg. Jan 2014	Posted 2014-05-29 10:21 AM Subject: RE: Human omeprazole used on a horse?
Regular Posts: 75	svincent - 2014-05-29 10:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! You haft to check your mg dosage... Dosage is 1.8 milligram per lb per day for 28 days and then .9 mg for 30 days. It still isn't economically to buy the human version because you need sooooo much.
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Douglas J Gordon Reg. Jun 2008	Posted 2014-05-29 10:35 AM Subject: RE: Human omeprazole used on a horse?
BHW's Lance Armstrong Posts: 11134 Location: Somewhere between S@%&# stirrer and Saint	2.28 grams of omeprazole per day for 28 -30 days.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-29 10:55 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret!
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-29 10:58 AM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work.
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Honeymoney Reg. Apr 2012	Posted 2014-05-29 11:26 AM Subject: RE: Human omeprazole used on a horse?
Fire Ant Peddler Posts: 2881	ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine.
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-29 11:41 AM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	Honeymoney - 2014-05-29 11:26 AM ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine. Gastrogard/Ulcergard contains specially formulated omeprazole that acts at the source of acid production. Unlike other, unproven products, which attempt to “coat” the stomach lining or neutralize acidity, GASTROGARD inhibits the proton pump that produces stomach acid. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. So those products that only neutralize the acid don't work on horses like they do humans.. you may see very minor improvements, but won't see a cure. So based on this information in order the CURE your horses ulcers the omeprazole MUST get into the bloodstream to be delivered to the proton pumps.. it can't just plug itself into microscopic holes on the outside lining of the stomach to plug the pumps or be swallowed to just neutralize the acid that is currently in the stomach. It certainly is designed to work just as I stated, not just from the inside of the stomach to neutalize, coat the stomach. It works pretty much the same way pain pills do.. you don't rub them on your head when it hurts, you swallow them, they get into your bloodstream and are delivered to the neutrons they are meant to block to stop the pain. Also just for FYI: Omeprazole is not an acid blocker for the stomach, it is a Proton Pump Inhibitor. It does not work like tums or rolaids. Edited by ACEINTHEHOLE 2014-05-29 11:45 AM
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svincent Reg. Feb 2012	Posted 2014-05-29 11:44 AM Subject: RE: Human omeprazole used on a horse?
The Resident Destroyer of Liberal Logic Location: PNW	SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! Bummer about not using them :( I hadn't converted the dosage to be equivalent to gastroguard. They are 250 ct bottles for $10.?? - I thought I was going to be so clever. Fail lol
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svincent Reg. Feb 2012	Posted 2014-05-29 11:45 AM Subject: RE: Human omeprazole used on a horse?
The Resident Destroyer of Liberal Logic Location: PNW	Also, I don't have a horse with ulcers at the moment - but if it was a smart deal I was going to STOCK UP for possible future ulcer problems :)
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-29 11:55 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	The drug Omeprazole is NOT absorbed in the stomach. The absorption of omeprazole takes place in the small intestine and is usually completed within 3–6 hr. Therefore, it needs to MAKE IT to the small intestine for it to work properly. The drug will NOT survive the acidic environment of the stomach - meaning, it will be ineffective before even reaching the small intestine. Yes, it does its work on the stomach, but it's not a coating for the stomach. It does indeed work by being absorbed into the bloodstream.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-29 12:00 PM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	ACEINTHEHOLE - 2014-05-29 12:41 PM Honeymoney - 2014-05-29 11:26 AM ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine. Gastrogard/Ulcergard contains specially formulated omeprazole that acts at the source of acid production. Unlike other, unproven products, which attempt to “coat” the stomach lining or neutralize acidity, GASTROGARD inhibits the proton pump that produces stomach acid. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. So those products that only neutralize the acid don't work on horses like they do humans.. you may see very minor improvements, but won't see a cure. So based on this information in order the CURE your horses ulcers the omeprazole MUST get into the bloodstream to be delivered to the proton pumps.. it can't just plug itself into microscopic holes on the outside lining of the stomach to plug the pumps or be swallowed to just neutralize the acid that is currently in the stomach. It certainly is designed to work just as I stated, not just from the inside of the stomach to neutalize, coat the stomach. It works pretty much the same way pain pills do.. you don't rub them on your head when it hurts, you swallow them, they get into your bloodstream and are delivered to the neutrons they are meant to block to stop the pain. Also just for FYI: Omeprazole is not an acid blocker for the stomach, it is a Proton Pump Inhibitor. It does not work like tums or rolaids. While I agree with the gist of your post, I will disagree with this statement: "Gastrogard/Ulcergard contains specially formulated omeprazole..." Wrong. Omeprazole is omeprazole is omeprazole. What is specially formulated is the CARRYING AGENT in the paste. Rather than an enteric coating on a pill, Merial has designed a buffering agent within the paste that changes the acidic environment of the stomach enough to carry the drug, omeprazole, safely to the small intestine, where absorption must occur.
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WalknFaith Reg. Jan 2014	Posted 2014-05-29 12:06 PM Subject: RE: Human omeprazole used on a horse?
Regular Posts: 75	ACEINTHEHOLE - 2014-05-29 11:41 AM Honeymoney - 2014-05-29 11:26 AM ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine. Gastrogard/Ulcergard contains specially formulated omeprazole that acts at the source of acid production. Unlike other, unproven products, which attempt to “coat” the stomach lining or neutralize acidity, GASTROGARD inhibits the proton pump that produces stomach acid. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. So those products that only neutralize the acid don't work on horses like they do humans.. you may see very minor improvements, but won't see a cure. So based on this information in order the CURE your horses ulcers the omeprazole MUST get into the bloodstream to be delivered to the proton pumps.. it can't just plug itself into microscopic holes on the outside lining of the stomach to plug the pumps or be swallowed to just neutralize the acid that is currently in the stomach. It certainly is designed to work just as I stated, not just from the inside of the stomach to neutalize, coat the stomach. It works pretty much the same way pain pills do.. you don't rub them on your head when it hurts, you swallow them, they get into your bloodstream and are delivered to the neutrons they are meant to block to stop the pain. Also just for FYI: Omeprazole is not an acid blocker for the stomach, it is a Proton Pump Inhibitor. It does not work like tums or rolaids. It does not work by getting in the blood. Yes it does get into the blood but it works by blocking the HPAT enzyme system and this whole chemical system takes place in the cells ETA: i should have said the cells lining the intestinal tract (parietal cells). I'm going to edit this again because I think its hard for people to understand. The omeprazole must get into the blood to treat the ulcers. It must make it past whatever stomach acid is currently in the stomach so that it can pass into the intestine unharmed and be absorbed into the bloodstream. It must get in the bloodstream and get back to the acid producing cells in the stomach only then can it prevent the HPAT enzyme system from producing acid. This is the only way to heal because your inhibiting the pump. Edited by WalknFaith 2014-05-29 12:45 PM
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-29 12:50 PM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	SuckerForHorses - 2014-05-29 12:00 PM ACEINTHEHOLE - 2014-05-29 12:41 PM Honeymoney - 2014-05-29 11:26 AM ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine. Gastrogard/Ulcergard contains specially formulated omeprazole that acts at the source of acid production. Unlike other, unproven products, which attempt to “coat” the stomach lining or neutralize acidity, GASTROGARD inhibits the proton pump that produces stomach acid. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. So those products that only neutralize the acid don't work on horses like they do humans.. you may see very minor improvements, but won't see a cure. So based on this information in order the CURE your horses ulcers the omeprazole MUST get into the bloodstream to be delivered to the proton pumps.. it can't just plug itself into microscopic holes on the outside lining of the stomach to plug the pumps or be swallowed to just neutralize the acid that is currently in the stomach. It certainly is designed to work just as I stated, not just from the inside of the stomach to neutalize, coat the stomach. It works pretty much the same way pain pills do.. you don't rub them on your head when it hurts, you swallow them, they get into your bloodstream and are delivered to the neutrons they are meant to block to stop the pain. Also just for FYI: Omeprazole is not an acid blocker for the stomach, it is a Proton Pump Inhibitor. It does not work like tums or rolaids. While I agree with the gist of your post, I will disagree with this statement: "Gastrogard/Ulcergard contains specially formulated omeprazole..." Wrong. Omeprazole is omeprazole is omeprazole. What is specially formulated is the CARRYING AGENT in the paste. Rather than an enteric coating on a pill, Merial has designed a buffering agent within the paste that changes the acidic environment of the stomach enough to carry the drug, omeprazole, safely to the small intestine, where absorption must occur. I guess you should take that up with Merial then, that was copied straight from their website. I will take the word of the company that developed the agent, and it being mixed in with the paste, would in my opinion, qualify as specially formulated since no one else has that formulation.
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-29 12:51 PM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	WalknFaith - 2014-05-29 12:06 PM ACEINTHEHOLE - 2014-05-29 11:41 AM Honeymoney - 2014-05-29 11:26 AM ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine. Gastrogard/Ulcergard contains specially formulated omeprazole that acts at the source of acid production. Unlike other, unproven products, which attempt to “coat” the stomach lining or neutralize acidity, GASTROGARD inhibits the proton pump that produces stomach acid. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. So those products that only neutralize the acid don't work on horses like they do humans.. you may see very minor improvements, but won't see a cure. So based on this information in order the CURE your horses ulcers the omeprazole MUST get into the bloodstream to be delivered to the proton pumps.. it can't just plug itself into microscopic holes on the outside lining of the stomach to plug the pumps or be swallowed to just neutralize the acid that is currently in the stomach. It certainly is designed to work just as I stated, not just from the inside of the stomach to neutalize, coat the stomach. It works pretty much the same way pain pills do.. you don't rub them on your head when it hurts, you swallow them, they get into your bloodstream and are delivered to the neutrons they are meant to block to stop the pain. Also just for FYI: Omeprazole is not an acid blocker for the stomach, it is a Proton Pump Inhibitor. It does not work like tums or rolaids. It does not work by getting in the blood. Yes it does get into the blood but it works by blocking the HPAT enzyme system and this whole chemical system takes place in the cells ETA: i should have said the cells lining the intestinal tract (parietal cells). I'm going to edit this again because I think its hard for people to understand. The omeprazole must get into the blood to treat the ulcers. It must make it past whatever stomach acid is currently in the stomach so that it can pass into the intestine unharmed and be absorbed into the bloodstream. It must get in the bloodstream and get back to the acid producing cells in the stomach only then can it prevent the HPAT enzyme system from producing acid. This is the only way to heal because your inhibiting the pump. Is that not what I just said?
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WalknFaith Reg. Jan 2014	Posted 2014-05-29 12:57 PM Subject: RE: Human omeprazole used on a horse?
Regular Posts: 75	I apologize ACEINTHEHOLE it sounded like you were telling people it was controlled somewhere else. Some people think that these cells are found in other locations in the body and that is the reason why it must get into the blood stream.
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-29 1:00 PM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	WalknFaith - 2014-05-29 12:57 PM I apologize ACEINTHEHOLE it sounded like you were telling people it was controlled somewhere else. Some people think that these cells are found in other locations in the body and that is the reason why it must get into the blood stream. Understood.. nope just saying they had to be carried to the Proton Pumps by the blood after absorption. Sorry for the confusion.
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-29 1:23 PM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	Just some more FYI on different types of acid medications: Omeprazole blocks for 12 hr a day. Ranitidine/cimitadine only block partially and only for about 4-5 hrs at a time. Nutricueticals and antacids only act on the acid in the stomach - so only about 30 min to 1 hr duration. Horses don't have a gall bladder so they produce acid all the time. We can get away with Tums etc because we only produce acid when we eat.
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Douglas J Gordon Reg. Jun 2008	Posted 2014-05-29 9:52 PM Subject: RE: Human omeprazole used on a horse?
BHW's Lance Armstrong Posts: 11134 Location: Somewhere between S@%&# stirrer and Saint	SuckerForHorses - 2014-05-29 12:00 PM ACEINTHEHOLE - 2014-05-29 12:41 PM Honeymoney - 2014-05-29 11:26 AM ACEINTHEHOLE - 2014-05-29 10:58 AM SuckerForHorses - 2014-05-29 10:55 AM svincent - 2014-05-29 11:09 AM The Costco near me has bottles of 20mg omeprazole pills on SUPER DUPER SALE! Can I use these on the horses? It's just omeprazole, nothing else - even missing the pricy gastroguard label!! No. For one, it would be cheaper to just buy GastroGard. 2.28 grams is 2,280 milligrams. Right now Walmart's price is $16.47 for a bottle of 20 mg tabs, 42 count. That's $0.02 per milligram. $0.02 * 2280 = $45.60 per day to dose a horse. GastroGard is cheaper than that by about $10.00 a day. Two, you cannot crush the pills up - that would ruin the enteric coating on the tablet, rendering them ineffective anyhow. Unless of course you can convince your horse to swallow them whole, and if that is the case, do share the secret! And to add to this.... those pills won't make it past the acid in the glandular stomach to be absorbed into their system. Gastrogard has a patented delivery agent that can withstand the acid to get the Omeprazole into the blood stream that nothing else has. So you may get a small amount of relief, but you would basically be throwing that money down the drain and still would not cure the ulcers. Remember, the most expensive medicine is the one that doesn't work. Omeprazole is an acid blocker for the stomach. While some is absorbed into the blood, it is certainly not designed to work from the blood stream if the effects are need in the stomach and intestine. Gastrogard/Ulcergard contains specially formulated omeprazole that acts at the source of acid production. Unlike other, unproven products, which attempt to “coat” the stomach lining or neutralize acidity, GASTROGARD inhibits the proton pump that produces stomach acid. With fewer active pumps, your horse’s stomach produces enough acid to break down food, but not the excess acid that causes ulcers. So those products that only neutralize the acid don't work on horses like they do humans.. you may see very minor improvements, but won't see a cure. So based on this information in order the CURE your horses ulcers the omeprazole MUST get into the bloodstream to be delivered to the proton pumps.. it can't just plug itself into microscopic holes on the outside lining of the stomach to plug the pumps or be swallowed to just neutralize the acid that is currently in the stomach. It certainly is designed to work just as I stated, not just from the inside of the stomach to neutalize, coat the stomach. It works pretty much the same way pain pills do.. you don't rub them on your head when it hurts, you swallow them, they get into your bloodstream and are delivered to the neutrons they are meant to block to stop the pain. Also just for FYI: Omeprazole is not an acid blocker for the stomach, it is a Proton Pump Inhibitor. It does not work like tums or rolaids. While I agree with the gist of your post, I will disagree with this statement: "Gastrogard/Ulcergard contains specially formulated omeprazole..." Wrong. Omeprazole is omeprazole is omeprazole. What is specially formulated is the CARRYING AGENT in the paste. Rather than an enteric coating on a pill, Merial has designed a buffering agent within the paste that changes the acidic environment of the stomach enough to carry the drug, omeprazole, safely to the small intestine, where absorption must occur. I really didn't want to point this out so I am glad you did. I was waiting for someone to post this. If you want to see if they really have anything special it will be written plainly in there patent, but it just sounds to me as their play on words for marketing purposes.
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Kaye Reg. Oct 2006	Posted 2014-05-29 10:44 PM Subject: RE: Human omeprazole used on a horse?
	ACEINTHEHOLE - 2014-05-29 12:23 PM Just some more FYI on different types of acid medications: Omeprazole blocks for 12 hr a day. Ranitidine/cimitadine only block partially and only for about 4-5 hrs at a time. Nutricueticals and antacids only act on the acid in the stomach - so only about 30 min to 1 hr duration. Horses don't have a gall bladder so they produce acid all the time. We can get away with Tums etc because we only produce acid when we eat. Omeprazole inhibits acid secretion up to 99% for 24hrs. On average they found that after the fifth day acid secretion was 90% for 24hrs. Hence the once a day dosing.
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grinandbareit Reg. Jan 2007	Posted 2014-05-30 12:12 AM Subject: RE: Human omeprazole used on a horse?
Go For It! Location: Texas	Well I can tell you this... I had a mare OTT that had terrible ulcers (years ago). I bought Prilosec OTC and drenched her 8 pills 1 X daily and her ulcers cleared up. I let the pills soak and made them into a paste. It worked and was WAY cheaper than the horse version.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 7:07 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	ACEINTHEHOLE - 2014-05-29 2:23 PM Just some more FYI on different types of acid medications: Omeprazole blocks for 12 hr a day. Ranitidine/cimitadine only block partially and only for about 4-5 hrs at a time. Nutricueticals and antacids only act on the acid in the stomach - so only about 30 min to 1 hr duration. Horses don't have a gall bladder so they produce acid all the time. We can get away with Tums etc because we only produce acid when we eat. Omeprazole - 24 hours Ranitidine - 8 hours
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 7:07 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	grinandbareit - 2014-05-30 1:12 AM Well I can tell you this... I had a mare OTT that had terrible ulcers (years ago). I bought Prilosec OTC and drenched her 8 pills 1 X daily and her ulcers cleared up. I let the pills soak and made them into a paste. It worked and was WAY cheaper than the horse version. And of course you have before and after scopes to substantiate your proof?
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-30 8:13 AM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	SuckerForHorses - 2014-05-30 7:07 AM ACEINTHEHOLE - 2014-05-29 2:23 PM Just some more FYI on different types of acid medications: Omeprazole blocks for 12 hr a day. Ranitidine/cimitadine only block partially and only for about 4-5 hrs at a time. Nutricueticals and antacids only act on the acid in the stomach - so only about 30 min to 1 hr duration. Horses don't have a gall bladder so they produce acid all the time. We can get away with Tums etc because we only produce acid when we eat. Omeprazole - 24 hours Ranitidine - 8 hours Well my info comes straight from Merial, as I have a friend that is a rep for them. This information is the information learned straight from their studies.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 8:59 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	Well then perhaps you should ask your friend why the GastroGard INSTRUCTIONS say to dose once per day, instead of every 12 hours?
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TurnLane Reg. May 2007	Posted 2014-05-30 9:36 AM Subject: RE: Human omeprazole used on a horse?
Pork Fat is my Favorite Posts: 3791 Location: The Oklahoma plains.	SuckerForHorses - 2014-05-30 7:07 AM grinandbareit - 2014-05-30 1:12 AM Well I can tell you this... I had a mare OTT that had terrible ulcers (years ago). I bought Prilosec OTC and drenched her 8 pills 1 X daily and her ulcers cleared up. I let the pills soak and made them into a paste. It worked and was WAY cheaper than the horse version. And of course you have before and after scopes to substantiate your proof? My question too
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FLITASTIC Reg. Jun 2012	Posted 2014-05-30 10:04 AM Subject: RE: Human omeprazole used on a horse?
Expert Posts: 5293	All this aside, I think its funny that you can give Ulcerguard OTC for half a tube, but need vets permission to give whole tube. lol Come on, it all needs to be OTC.
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-30 10:07 AM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	SuckerForHorses - 2014-05-30 8:59 AM Well then perhaps you should ask your friend why the GastroGard INSTRUCTIONS say to dose once per day, instead of every 12 hours? Because you only want to shut the pumps off enough to reduce acid production to a level that will not create ulcers (allow current ulcers to heal)... you still have to have enough acid to digest food. If you shut them off completely you will end up with colic issues.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 10:22 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	ACEINTHEHOLE - 2014-05-30 11:07 AM SuckerForHorses - 2014-05-30 8:59 AM Well then perhaps you should ask your friend why the GastroGard INSTRUCTIONS say to dose once per day, instead of every 12 hours? Because you only want to shut the pumps off enough to reduce acid production to a level that will not create ulcers (allow current ulcers to heal)... you still have to have enough acid to digest food. If you shut them off completely you will end up with colic issues. Show me the citation for this information. The AMOUNT of omeprazole given is what determines how many pumps get shut down. The amount in a tube of GastroGard is enough to shut X number down for 24 HOURS. That's why it's a 24-hour dosing regimen. Edited by SuckerForHorses 2014-05-30 10:27 AM
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 10:24 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	FLITASTIC - 2014-05-30 11:04 AM All this aside, I think its funny that you can give Ulcerguard OTC for half a tube, but need vets permission to give whole tube. lol Come on, it all needs to be OTC. Just buy UlcerGard, and give a full tube. No script required. There is the same amount of omeprazole in a tube of UlcerGard as there is in GastroGard. Its the same idea as for human ibuprofen - you can only get 800 mg tablets with a prescription but you can buy OTC a bottle of it, and take 4, 200 mg tablets on your own.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 10:25 AM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	UlcerGard is cheaper per tube also, so I'm not really sure why anybody even purchases GastroGard tubes! LOL!
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ACEINTHEHOLE Reg. Apr 2005	Posted 2014-05-30 10:45 AM Subject: RE: Human omeprazole used on a horse?
Tough Patooty Posts: 2615 Location: Sperry, OK	SuckerForHorses - 2014-05-30 10:22 AM ACEINTHEHOLE - 2014-05-30 11:07 AM SuckerForHorses - 2014-05-30 8:59 AM Well then perhaps you should ask your friend why the GastroGard INSTRUCTIONS say to dose once per day, instead of every 12 hours? Because you only want to shut the pumps off enough to reduce acid production to a level that will not create ulcers (allow current ulcers to heal)... you still have to have enough acid to digest food. If you shut them off completely you will end up with colic issues. Show me the citation for this information. The AMOUNT of omeprazole given is what determines how many pumps get shut down. The amount in a tube of GastroGard is enough to shut X number down for 24 HOURS. That's why it's a 24-hour dosing regimen. I guess since you are the one that works for the company that did the studies and has access to all the information for specifics on how the product works, there is no reason for me to provide you with anything.. I am sure you already have it. On the same note, why don't you provide me with citations detailing that Omeprazole works for 24 hours in the horse NOT human as you have stated, and with the information as to why it is labeled for 24 hr dosing and not 12, as I am certain you have that as well. I am sure the manufacturer of the product knows how the products works on HORSES better than you do, and all my information is straight from them.
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SuckerForHorses Reg. Apr 2014	Posted 2014-05-30 12:25 PM Subject: RE: Human omeprazole used on a horse?
Extreme Veteran Posts: 330	"Pharmacodynamics: In a study of pharmacodynamic effects using horses with gastric cannulae, secretion of gastric acid was inhibited in horses given 4 mg omeprazole/kg/day. After the expected maximum suppression of gastric acid secretion was reached (5 days), the actual secretion of gastric acid was reduced by 99%, 95% and 90% at 8, 16, and 24 hours, respectively." http://www.drugs.com/pro/gastrogard.html Gastric acid production was still reduced by 90% after 24 hours...that's why it's not needed every 12. After 24 hours, still 90% of the acid is not being produced. So yes, it does do its intended job (to reduce acid production) for 24 hours. In fact, after 24 hours, it's hardly begun to wear off/stop working as intended. Efficacy of omeprazole paste for prevention of gastric ulcers in horses in race training... CONCLUSIONS AND CLINICAL RELEVANCE; Results indicated that omeprazole administered at a dosage of 1 mg/kg, PO, every 24 hours for 28 days was effective for prevention of gastric ulcers in horses starting race training. http://www.ncbi.nlm.nih.gov/pubmed/15906568
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