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Expert
Posts: 2685
   
| Gave my horse pentosan IM on Monday. She came up yesterday afternoon with a tree truck neck on one side (injection side). I did not notice this Tuesday or Wednesday. I did not ride her those days but its kind of hard to miss. I don't know how a reaction could take that long but I have no idea what else it could be. Vet thinks a bite of some sort since it was a whole 2 days after the injection. Gave NSAID, cold hosed, gave dex. This morning I cold hosed and applied a DMSO/ Furacin sweat. It seemed to help. I gave the injection in the appropriate spot on the neck but the swelling is most warm, tender and large about 2 inches behind the ears.
Idk guys.... just thought I would post in case someone else had a reaction to it
Dry pic is when I found her. Wet pic with sweat was right after I put the sweat on at 9am this morning.
Edited by RoaniePonie11 2014-08-22 12:40 PM
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Extreme Veteran
Posts: 330
| So it's swollen on the same side as the injection site but not in the same location as the injection?
If its not in the same spot on the neck, I wouldn't think it was from the injection itself. |
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 Shelter Dog Lover
Posts: 10277
| Abcess from injection? My vet had me apply hot pack several times a day ans spray area with a mixture they gave me. Horse absorbed the abcess in about 5 days. |
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Expert
Posts: 2685
| SuckerForHorses - 2014-08-22 12:17 PM
So it's swollen on the same side as the injection site but not in the same location as the injection?
If its not in the same spot on the neck, I wouldn't think it was from the injection itself.
correct
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Expert
Posts: 2685
| rodeomom3 - 2014-08-22 12:22 PM
Abcess from injection? My vet had me apply hot pack several times a day ans spray area with a mixture they gave me. Horse absorbed the abcess in about 5 days.
do you know what the mixture was? |
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 Lady Di
Posts: 21556
Location: Oklahoma | Mine did that from an injection of lactanase. Vet thought it leaked out of the vein into the tissue and abscessed. Had me paint the bump for 5 days with DMSO, but lump was gone after 3 days of painting. |
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Expert
Posts: 2685
| How often did you paint? Once or twice a day? |
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Hungarian Midget Woman
Location: Midwest | It could have leaked into the vein and caused a reaction. I believe pentosan is labeled only for IM or IA |
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The Advice Guru
Posts: 6419
| Go to a vet as it could be necrotizing faciatis (sp). This mainly occurs with banamine, but I have had it happen with penicillin twice. It can occur with any injection.
The vet needs to drain it |
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Expert
Posts: 2685
| I have been to the vet :) that's who told me to sweat her. I thought the infection you are talking about gets much worse than this much faster? |
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Shelter Dog Lover
Posts: 10277
| RoaniePonie11 - 2014-08-22 12:27 PM rodeomom3 - 2014-08-22 12:22 PM Abcess from injection? My vet had me apply hot pack several times a day ans spray area with a mixture they gave me. Horse absorbed the abcess in about 5 days. do you know what the mixture was?
Sorry, no it was a DMSO mixture, don't know what else was in it. They mixed it up for me. I bought hot packs from Walmart, zapped them in the microwave and used ace bandages to hold them in place on his neck. If you do this be sure they are not too hot or put a cloth between the hot pack and neck. I had to stay with him to keep them in place. It helped to hang a hay bag of alfalfa. |
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Hungarian Midget Woman
Location: Midwest | Did you pull back to check for blood in the syringe before injecting, or did you just Im it straight out? |
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 Experienced Mouse Trapper
Posts: 3106
Location: North Dakota | Should always use a needle and inch and a half long on IM injections in the neck. Just FYI! |
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 Pork Fat is my Favorite
Posts: 3791
Location: The Oklahoma plains. | And correct me if I am wrong but isnt Pentosan compound only, therefore not the FDA approved product? So it could be a reaction to incorrect ingredients or level dose like the polo horses received in Florida that died. |
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Hungarian Midget Woman
Location: Midwest | TurnLane - 2014-08-22 3:22 PM And correct me if I am wrong but isnt Pentosan compound only, therefore not the FDA approved product? So it could be a reaction to incorrect ingredients or level dose like the polo horses received in Florida that died.
It's compounded. However, if you order from a good pharmacy you should not worry. The compounding pharmacies are still strictly regulated. |
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Expert
Posts: 2685
| Hi everyone. Thank you for all of the replies. I am about to go out and check on her and cold hose her. I do not feel it is the injection because the swelling did not start there. It may have been it though you never know. I do know I have the injection properly. That is my actual day job. I'm hoping this is no big deal. My vet seems not to be worried due to our improvement and the details I have told her. She seems confident it was a bite and we are on the right track. |
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 Voice of Reason
Location: NOT at Wal Mart | RoaniePonie11 - 2014-08-22 1:52 PM Hi everyone. Thank you for all of the replies. I am about to go out and check on her and cold hose her. I do not feel it is the injection because the swelling did not start there. It may have been it though you never know. I do know I have the injection properly. That is my actual day job. I'm hoping this is no big deal. My vet seems not to be worried due to our improvement and the details I have told her. She seems confident it was a bite and we are on the right track.
I agree, IF it was clostridium the horse would be in big trouble by now, good luck. |
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 You get what you give
Posts: 13030
Location: Texas | I don't think it leaked into a vein… the jugular vein travels from the head to the heart, so it getting into the vein would not cause an abscess upstream.
I think you are on the right track. I have never given pentosan so I have no experience with any reactions.
One thought I have is if it traveled via the lymphatic system. I gave exceed antibiotics once from a bad batch, and my horse had a very painful reaction that traveled in her lymphatic system. Her back legs were all stumpy in the stifle and gaskin area and her neck was real swollen and hot where I gave the shot. |
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Expert
Posts: 2685
| Hey guys. Thanks all. Thankfully I am only seeing issues and feeling heat in her neck. We are about 50% down now. I cold hosed and iced and re-painted this evening. She seems to be feeling better. |
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boon
Posts: 1
| Had 5 horses so far have reactions 2 days after giving pentosan / glucosamine. Swollen neck (NOT at injection site), entire body stiff, some with high fever, one with high respiration. Other horses in our area having reactions too. Know of one that died after IV injection....we give IM. |
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Hungarian Midget Woman
Location: Midwest | TrixiePony - 2014-08-26 10:33 AM Had 5 horses so far have reactions 2 days after giving pentosan / glucosamine. Swollen neck (NOT at injection site), entire body stiff, some with high fever, one with high respiration. Other horses in our area having reactions too. Know of one that died after IV injection....we give IM.
Sounds like a contamination issue with the lot |
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Pork Fat is my Favorite
Posts: 3791
Location: The Oklahoma plains. | barrelracr131 - 2014-08-22 3:29 PM TurnLane - 2014-08-22 3:22 PM And correct me if I am wrong but isnt Pentosan compound only, therefore not the FDA approved product? So it could be a reaction to incorrect ingredients or level dose like the polo horses received in Florida that died. It's compounded. However, if you order from a good pharmacy you should not worry. The compounding pharmacies are still strictly regulated.
http://www.raps.org/regulatoryDetail.aspx?id=10002
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Experienced Mouse Trapper
Posts: 3106
Location: North Dakota | TurnLane - 2014-08-26 11:46 AM
barrelracr131 - 2014-08-22 3:29 PM TurnLane - 2014-08-22 3:22 PM And correct me if I am wrong but isnt Pentosan compound only, therefore not the FDA approved product? So it could be a reaction to incorrect ingredients or level dose like the polo horses received in Florida that died. It's compounded. However, if you order from a good pharmacy you should not worry. The compounding pharmacies are still strictly regulated.
Wedgewood received a warning letter "for compounding without having received valid prescriptions for individually identifiable patients." So in my interpretation is that the individual they sold product to wasn't completely identified. For example my perscription says my horses name on the vial along with me as the owner and the prescribing vet. I would bet FDA found discrepencies in their "policy and regulations" that could be interpreted differently depending on who was reading the policy. So the vial might have said "smith's dog" instead of stubby......
I'm greatful the warning letters were not for "floating particulate" Even the big Pharmacies run into trouble every now and then......
Wondering about this new outbreak....where did that Pentosan/Glucosamine come from?? |
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Hungarian Midget Woman
Location: Midwest | LMS - 2014-08-26 11:54 AM
TurnLane - 2014-08-26 11:46 AM
barrelracr131 - 2014-08-22 3:29 PM TurnLane - 2014-08-22 3:22 PM And correct me if I am wrong but isnt Pentosan compound only, therefore not the FDA approved product? So it could be a reaction to incorrect ingredients or level dose like the polo horses received in Florida that died. It's compounded. However, if you order from a good pharmacy you should not worry. The compounding pharmacies are still strictly regulated.
Wedgewood received a warning letter "for compounding without having received valid prescriptions for individually identifiable patients." So in my interpretation is that the individual they sold product to wasn't completely identified. For example my perscription says my horses name on the vial along with me as the owner and the prescribing vet. I would bet FDA found discrepencies in their "policy and regulations" that could be interpreted differently depending on who was reading the policy. So the vial might have said "smith's dog" instead of stubby......
I'm greatful the warning letters were not for "floating particulate" Even the big Pharmacies run into trouble every now and then......
Wondering about this new outbreak....where did that Pentosan/Glucosamine come from??
As with anything, be careful who you purchase from.
I guess I should have clarified that. Not all pharmacies are created equal.
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Expert
Posts: 2685
| Ok I made phone calls. Waiting on a call from the vet. We shall see. |
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