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Expert
Posts: 2685
   
| So fumbling through a smartpak magazine the other day I noticed where it commented about the over production of acid after stopping gastrogard. I had just treated my mare with it and out loud said wait what? What get sitting there said yes that's why they want you to treat for 28 days to let everything in there heal so when the acid comes back with vengeance it's not on open ulcers.
Question- have you ever heard of that
Question- those that have used it what do you do to prepare for it, help your horse when that happens ect
Question- haas the acid coming back so much ever caused another ulcer and pretty much screwed the whole reason you used it?
Thanks. Just kinda got me worried... |
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The Advice Guru
Posts: 6419
 
| I have never heard of overproduction.
The mechanism of action of omeprazole is to inhibit the proton pump from secreting acid, so when omeprazole is removed the pump will start pumping acid again.
For a few minutes there may be an overproduction till the ph of the stomach is back to normal and the cells trigger the pump to maintain the status quo
I just read in my equine clinical pharmacology text, and overproduction was not listed as a precaution for weaning of the drug
It actually said 88% of the population the ulcers did not reoccur after treatment
Edited by cheryl makofka 2015-01-11 12:56 PM
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Expert
Posts: 2685
| ok thank you. I wonder why it said that in the magazine.... |
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 BHW's Lance Armstrong 
Posts: 11134
Location: Somewhere between S@%&# stirrer and Saint | If you think your horse has ulcers you may want to do your own research.
I can't advertise that omeprazole powder cures ulcers but you can do your own research. You can contact me at the email address below. |
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Veteran
Posts: 182
| I recently used Gastrogard for 28 days on my mare. She improved immediately and began eating her feed and obviously feeling better. Within 3-4 days after finishing treatment she is back to eating part or none of her grain and acting nervous again. She is on Exceed 6 Way daily. Have tried aloe Vera juice in the past but it doesn't do any good unless she eats her feed. |
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Expert
Posts: 3514
| Digestive ULR is what I use for ulcers. Was told by a vet that gastroguard can cause a horse to bleed and he also mentioned over production of acid. |
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 Veteran
Posts: 160
Location: Outside of Larryville, KS | I have absolutely heard of overproduction of acid after the omeprazole is stopped, there is research out there that shows this. You just have to weigh the risks. You can try stomach buffers to help like dePaolos Excel tm, or aloe Vera juice, I have also heard papaya works well too. I try and taper down the amount of Omeprazole at the end of the treatment to help with this as well. You can also give extra alfalfa to absorb the acid. |
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Expert
Posts: 2685
| thank you everyone. I bought some more because she is back to acting poopy when during treatment she was the happiest horse around. I figure I'll give her another couple of days of full dose and go down to the "maintenance" (1/4 tube) for a little while. I can't afford for her to live on this stuff. I thought about trying to have powder compounded. I had heard about that in the past but its still omep, ill still have the acid problem. I wonder about going the THE GastroPlus route would be better. I have heard good things about it but never used it for ulcers. |
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The Advice Guru
Posts: 6419
| HDNAQHA - 2015-01-11 8:36 PM
I have absolutely heard of overproduction of acid after the omeprazole is stopped, there is research out there that shows this. You just have to weigh the risks. You can try stomach buffers to help like dePaolos Excel tm, or aloe Vera juice, I have also heard papaya works well too. I try and taper down the amount of Omeprazole at the end of the treatment to help with this as well. You can also give extra alfalfa to absorb the acid.
Can you please site the research articles as I would like to read them
Thanks |
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 I'm Cooler Offline
Posts: 6387
Location: Pacific Northwest | I've never heard of that...but after I treated with UlcerCure OTC I started my mare on SmartGut Ultra and haven't had a problem. It's been almost a year. But I hadn't ever heard of it actually causing overproduction, I just figured since my mare was ulcer-prone that some type of daily supplement might help keep them away.
ETA I also changed her feed...took her off grain and she just gets beet pulp and alfalfa pellets, and hay of course.
Edited by livexlovexrodeo 2015-01-11 11:22 PM
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The Advice Guru
Posts: 6419
| RoaniePonie11 - 2015-01-11 8:41 PM
thank you everyone. I bought some more because she is back to acting poopy when during treatment she was the happiest horse around. I figure I'll give her another couple of days of full dose and go down to the "maintenance" (1/4 tube) for a little while. I can't afford for her to live on this stuff. I thought about trying to have powder compounded. I had heard about that in the past but its still omep, ill still have the acid problem. I wonder about going the THE GastroPlus route would be better. I have heard good things about it but never used it for ulcers.
You need to find the root of the cause of the ulcers.
Feed is generally the main causitive factor.
The ph of the hind gut can cause ulcers. This is why probiotics, low NSC, high fat and forage 24/7 are your best bet to eliminate ulcers long term.
Stress, even stalling can induce enough stress to cause ulcers, I have one who cannot be stalled as she develops ulcers immediately.
Pain causes ulcers.
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Expert
Posts: 2685
| cheryl makofka - 2015-01-11 11:06 PM
RoaniePonie11 - 2015-01-11 8:41 PM
thank you everyone. I bought some more because she is back to acting poopy when during treatment she was the happiest horse around. I figure I'll give her another couple of days of full dose and go down to the "maintenance" (1/4 tube) for a little while. I can't afford for her to live on this stuff. I thought about trying to have powder compounded. I had heard about that in the past but its still omep, ill still have the acid problem. I wonder about going the THE GastroPlus route would be better. I have heard good things about it but never used it for ulcers.
You need to find the root of the cause of the ulcers.
Feed is generally the main causitive factor.
The ph of the hind gut can cause ulcers. This is why probiotics, low NSC, high fat and forage 24/7 are your best bet to eliminate ulcers long term.
Stress, even stalling can induce enough stress to cause ulcers, I have one who cannot be stalled as she develops ulcers immediately.
Pain causes ulcers.
She is on low grain, high forage, eats at least 10lbs baled alfalfa a day, stays turned out- just comes in to eat, had her vet checked enough that all vets within 50mile radius hate me. Just took her last Friday to be checked out and flexed her, trotted her, lunged her ect. I'm not real sure where to go from there.... |
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Veteran
Posts: 160
Location: Outside of Larryville, KS | Google acid rebound effect in horses, there are several articles about it and some are by DVMs and are clinical research articles. I found it very helpful in my approach with ulcers and horses. |
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 Porta Potty Pants
Posts: 2600
| ktbracer - 2015-01-11 5:35 PM
I recently used Gastrogard for 28 days on my mare. She improved immediately and began eating her feed and obviously feeling better. Within 3-4 days after finishing treatment she is back to eating part or none of her grain and acting nervous again. She is on Exceed 6 Way daily. Have tried aloe Vera juice in the past but it doesn't do any good unless she eats her feed.
I had my horse on Exceed as well. Made him not so nice … nervous nervous nervous and miserable to deal with - spooky, and I couldn't even get my saddle on him. I had to go back to running him around the round pen for exercise - couldn't put my saddle on him tied at the trailer - he would pull back. I took him off and it's taken several weeks for him to return close to normal.
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Question about using GastroGard (and products like it)