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 Regular
Posts: 56
Location: Savannah, Tennessee | I am starting my 12 year old gelding on monthly Adequan IM injections for prevention. He currently has no joint issues, has been on oral joint supplements for prevention in the past. Will I need to start with the loading dose? I'd love to hear personal experiences. The vet said with no joint problems I could just start with monthly injections. However, I have also read online that it is just a waste of money without the loading dose.
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Blessed 
  
Location: Here | Absolutely you do a loading dose. Because if you don't you might as well don't do it. You have to get the blood levels up and then maintain them |
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 Expert
Posts: 5293
| It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. |
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Extreme Veteran
Posts: 576
| I do a loading dose once or twice a year and no monthly shots. |
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Blessed
Location: Here | FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
? Do you have a link on this? I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days. I would love to learn more |
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Expert
Posts: 5293
| SG. - 2015-09-05 6:06 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
? Do you have a link on this? I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days. I would love to learn more
I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly. |
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Regular
Posts: 56
Location: Savannah, Tennessee | Thank you for the replies. I did the first shot yesterday and will go ahead and do the full loading dose, and then go from there to decide about monthly or doing the 7 shot series once or twice a year. |
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 Veteran
Posts: 268
| FLITASTIC - 2015-09-05 11:47 PM
SG. - 2015-09-05 6:06 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
? Do you have a link on this? I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days. I would love to learn more
I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.
My vet also told me this as well. I have switched from loading dose and monthly to loading dose 2x a year and an seeing better results. |
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Veteran
Posts: 150
| loading dose every 4days or 7?, |
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Queen Bean of Ponyland
Posts: 24955
Location: WYOMING | FLITASTIC - 2015-09-05 8:17 PM
It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
This is what I have been hearing. |
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Expert
Posts: 1611
| FLITASTIC - 2015-09-06 12:47 AM
SG. - 2015-09-05 6:06 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
? Do you have a link on this? I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days. I would love to learn more
I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.
He is correct call a rep of the company |
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Blessed
Location: Here | FLITASTIC - 2015-09-05 11:47 PM SG. - 2015-09-05 6:06 PM FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. ? Do you have a link on this? I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days. I would love to learn more I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.
Thank you for this info |
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 Born not Made
Posts: 2937
Location: North Dakota | FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Edited by r_beau 2015-09-06 6:24 PM
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Expert
Posts: 5293
| r_beau - 2015-09-06 4:17 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see. |
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 You get what you give
Posts: 13030
Location: Texas | FLITASTIC - 2015-09-06 9:42 PM
r_beau - 2015-09-06 4:17 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.
whats Curost? |
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 My Heart Be Happy
Posts: 9159
Location: Arkansas | casualdust07 - 2015-09-06 10:17 PM
FLITASTIC - 2015-09-06 9:42 PM
r_beau - 2015-09-06 4:17 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.
whats Curost?
Herbie, come forth!!! |
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Hungarian Midget Woman
Location: Midwest | casualdust07 - 2015-09-06 10:17 PM
FLITASTIC - 2015-09-06 9:42 PM
r_beau - 2015-09-06 4:17 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.
whats Curost?
An herbal supplement |
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You get what you give
Posts: 13030
Location: Texas | barrelracr131 - 2015-09-07 6:40 AM
casualdust07 - 2015-09-06 10:17 PM
FLITASTIC - 2015-09-06 9:42 PM
r_beau - 2015-09-06 4:17 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.
whats Curost?
An herbal supplement
oh ok thanks |
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Blessed
Location: Here | I went to the manufacturer as you suggested and yes the directions have changed since I read it last.
Wow
Studies show that administering Adequan®i.m. as recommended—500 mg intramuscularly once every four days for 28 days or seven treatments—better than results with four-injection series.*
http://www.adequan.com/recommended_dosage.aspx
http://www.adequan.com/clinical_studies.aspx
I have been sorta doing this with one of my older mares, just because it seems to work. I had been doing a box every 4 days then she would get really good and about 3 months later I would need to do it again. So I will continue. Thanks for the heads up that this has changed
Edited by SG. 2015-09-07 10:30 AM
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Born not Made
Posts: 2937
Location: North Dakota | r_beau - 2015-09-06 6:17 PM FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit. My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year.
So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.
To the OP: YES you need to do a loading dose, regardless.
Got a response from my other vet.
He said to do the loading dose in the spring, and then every month thereafter.
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Expert
Posts: 2685
| My mare is 6 and a big ole baby about her hocks and stifles (xrays are clean) and Adequan has done her wonders. I do the loading dose twice a year plus a round or two of pentosan. I don't do feed throughs' other than MSM simply because its a proven anti-inflammatory of all connective tissues (muscles were my main concern). |
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 Elite Veteran
Posts: 999
Location: Sunny So Cal | I do the loading dose twice a year and then maintenance doses throughout the months in between as well as feed JointFLEX. |
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Regular
Posts: 54
| Perhaps it depends on the horse and the reason why we are giving it as to which way is best to administer it.
I have had 2 reputable vets recommend loading dose for 28 days and then 1x monthly after to keep my arthritic gelding comfortable.
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 Jr. Detective
Location: Beggs, OK | SG. - 2015-09-07 10:28 AM I went to the manufacturer as you suggested and yes the directions have changed since I read it last.
Wow
Studies show that administering Adequan®i.m. as recommended—500 mg intramuscularly once every four days for 28 days or seven treatments—better than results with four-injection series.*
http://www.adequan.com/recommended_dosage.aspx
http://www.adequan.com/clinical_studies.aspx
I have been sorta doing this with one of my older mares, just because it seems to work. I had been doing a box every 4 days then she would get really good and about 3 months later I would need to do it again. So I will continue. Thanks for the heads up that this has changed
I asked Dr. Major about this exact thing when I was there having him look Fiesty over. We had done the loading dose on her in February. He said that the loading dose is sufficient unless they show that they are needing more support, and even then we probably need to look at an alternative. Twice a year is overkill. |
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 "Spaz-tacular"!!
Posts: 20309
Location: Bennett, CO | Im Unclear of what you mean- Is Dr. Major reccomending the loading dose 1x per year and thats it?
He is my Go-To when it is lamness related.. I haul from Colorado to see him!
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Jr. Detective
Location: Beggs, OK | gotothewhip - 2015-09-10 10:51 AM Im Unclear of what you mean- Is Dr. Major reccomending the loading dose 1x per year and thats it?
He is my Go-To when it is lamness related.. I haul from Colorado to see him!
That's what he told me when I asked him about how to manage my mare after having a bone fragment removed from her ankle. He said if I felt like she was uncomfortable and needed it I could give it to her once a month, but he didn't see the value in giving it to her just because. |
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Adequan... Loading dose or Not?