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 Don't Wanna Make This Awkward
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Location: Texas | I'm currently feeding omeprazole to treat for suspected ulcers.. Im going to order THE gastroplus, but I won't be able to get that before I leave for this weekends run. So i'm looking for something that you don't have to order, something I could get from tractor supply or something from walmart. Any ideas ? Just something extra to help soothe the stomach. I've seen a lot of ulcer posts the past week so hopefully someone knows something. | |
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 Elite Veteran
Posts: 878
 
Location: "...way down south in the Everglades..." | I use Ulcerguard and I know the one feed store here carries it. I haven't seen it at TSC but you may want to call around to your local feed stores.
eta: I guess I should read that you're already using omeprazole...sorry, that would be the same.
I had someone tell me she gives her horse Tums but I've never tried it or looked into it further.
Edited by Speedy Buckeye Girl 2015-10-07 1:37 PM
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 I hate cooking and cleaning
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Location: Jersey Girl | Jailbreak. | |
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Member
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| Jailbreak has worked wonders on my gelding | |
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 Elite Veteran
Posts: 1037
| fulltiltfilly - 2015-10-07 1:43 PM
Jailbreak.
Can you tell me your experience with Jailbreak? I used it this past weekend for my gelding just to settle his stomach, and Im not sure if I gave it too far out or if I needed a follow up dose, but he got nutty on me.. | |
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 Expert
Posts: 1525
| you might see if your vet sells Ranitidine in paste form...a vet here does and its a nice "extra" to give a couple hours before a run. But really you could probably give him the omeprazole in a small thing of oats or grain or however you typically feed it two hours out and it be just as good...or if you didnt want to feed then you might just be able to mix it with water and corn/vegetable oil in a syringe and give it like a paste.
Edited by MOTIVATED 2015-10-07 1:49 PM
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Elite Veteran
Posts: 667
| MOTIVATED - 2015-10-07 1:47 PM
you might see if your vet sells Ranitidine in paste form...a vet here does and its a nice "extra" to give a couple hours before a run. But really you could probably give him the omeprazole in a small thing of oats or grain or however you typically feed it two hours out and it be just as good...or if you didnt want to feed then you might just be able to mix it with water and corn/vegetable oil in a syringe and give it like a paste.
I buy rantidine from walmart and soak 20 pills in water or aloe vera juice, in a syringe, and then squirt it in their mouth. Sometimes on their feed if I am in a hurry. I do this twice a day. On race day, I use pepto bismol.
Edited by TNcowgirl88 2015-10-07 2:22 PM
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Don't Wanna Make This Awkward
Posts: 3106
Location: Texas | TNcowgirl88 - 2015-10-07 2:20 PM MOTIVATED - 2015-10-07 1:47 PM you might see if your vet sells Ranitidine in paste form...a vet here does and its a nice "extra" to give a couple hours before a run. But really you could probably give him the omeprazole in a small thing of oats or grain or however you typically feed it two hours out and it be just as good...or if you didnt want to feed then you might just be able to mix it with water and corn/vegetable oil in a syringe and give it like a paste. I buy rantadine from walmart and soak 20 pills in water or aloe vera juice, in a syringe, and then squirt it in their mouth. Sometimes on their feed if I am in a hurry. I do this twice a day. On race day, I use pepto bismol.
How much pepto bismal do you give a horse? | |
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Elite Veteran
Posts: 667
| outrundaizy - 2015-10-07 2:21 PM
TNcowgirl88 - 2015-10-07 2:20 PM MOTIVATED - 2015-10-07 1:47 PM you might see if your vet sells Ranitidine in paste form...a vet here does and its a nice "extra" to give a couple hours before a run. But really you could probably give him the omeprazole in a small thing of oats or grain or however you typically feed it two hours out and it be just as good...or if you didnt want to feed then you might just be able to mix it with water and corn/vegetable oil in a syringe and give it like a paste. I buy rantadine from walmart and soak 20 pills in water or aloe vera juice, in a syringe, and then squirt it in their mouth. Sometimes on their feed if I am in a hurry. I do this twice a day. On race day, I use pepto bismol.
I have never been told----- I will probably get flamed for that ---- but I just fill a big syringe full up. I would say maybe 20CC's. Now whether that is enough to tell a difference, or too much, I don't know. But, it seems to help my guy.
Edited by TNcowgirl88 2015-10-07 2:25 PM
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Veteran
Posts: 113
| Omeprazole takes days to work and needs to be fed consistently, but will heal ulcers. It's worthless if you're just giving it as a pre race "boost".
Ranitidine will block acid within a few hours. | |
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I AM being nice
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Location: MD | Even though it is not recommended use, I have had great results giving OxyUlcer2 hours before my run on race day. | |
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Expert
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Location: WI | runaround - 2015-10-07 3:23 PM Omeprazole takes days to work and needs to be fed consistently, but will heal ulcers. It's worthless if you're just giving it as a pre race "boost". Ranitidine will block acid within a few hours.
Did you see a study or something on this? I can't find anything. Didn't know you had to build omep up in their system. | |
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Expert
Posts: 1525
| linds - 2015-10-07 4:32 PM runaround - 2015-10-07 3:23 PM Omeprazole takes days to work and needs to be fed consistently, but will heal ulcers. It's worthless if you're just giving it as a pre race "boost". Ranitidine will block acid within a few hours. Did you see a study or something on this? I can't find anything. Didn't know you had to build omep up in their system.
I thought it would work pretty quickly too...I'm curious as to where the info came from. I am going to have to go back and do some research myself...I may have been wrong this entire time. | |
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Expert
Posts: 1525
| linds - 2015-10-07 4:32 PM runaround - 2015-10-07 3:23 PM Omeprazole takes days to work and needs to be fed consistently, but will heal ulcers. It's worthless if you're just giving it as a pre race "boost". Ranitidine will block acid within a few hours. Did you see a study or something on this? I can't find anything. Didn't know you had to build omep up in their system.
 3-5 days...runaround is absolutely right....I didnt know either.
Omeprazole? – I heard it in conjunction with treatment for gastric ulcers in horses. I started searching on the internet and what I found made me curious.
Omeprazole was first used in humans because of its acid-minimizing function in the stomach environment. Diseases like the Peptic Ulcer Disease (PUD), the Gastroesophageal Reflux Disease (GERD) (mucosal damage at the esophagus) or the Zollinger-Ellison Syndrome (production of the hormone gastrin which causes excess-production of HCL) are treated with this component. (Wikipedia 2007)
The interesting thing is that nausea (vomiting) and abdominal pain are among the most common adverse effects of the usage of omeprazole in humans. (Wikipedia 2007) BUT abdominal pain (caused by gas) in horses leads to colic and as far as I know a horse which vomits will be dead in a foreseeable period of time! So what does omeprazole do in the horses’ body and what are its side effects?
Omeprazole is one of the proton pump inhibitors used for the treatment of Equine Gastric Ulcer Syndrome (EGUS). Lesions (ulcers) develop when there is an imbalance in the stomach environment of protective and inciting factors of the stomach mucosa. (Murray et al. 1989, Nappert et al. 1989) Acid does play an important role as it is the main factor damaging the stomach walls. (Murray et al. 1989, Nappert et al. 1989, Mertz 1991) (For further information about the syndrome in horses see issue 1/2007- Equine Gastric Ulcer Syndrome). This is why the treatments of the common syndrome mainly try to increase the pH of the stomach environment which drops because of the increased acid content.
Antacids for instance are neutralizing the acid in the stomach, bismuth compounds are having little neutralizing capacity and do protect the gastric cells, prostaglandin is inhibiting the secretion of acid and therefore increases the pH of the stomach but also stimulates the secretion of mucus and bicarbonate and provides cytoprotection for the gastric mucosa. These agents could – regarding their function – all be useful in healing of ulcers but at the moment there is insufficient data about these agents and their effects on gastric ulcers in horses although they can be found as ingredients in products for the treatment of EGUS. (Picavet 2002, Marqués 2007)
H2 receptor antagonists (like cimetidine, ranitidine, nizatidine and famotidine) are having also an inhibiting function on the secretion of acid. Especially, ranitidine is used in the treatment of horses. It is proven to be effective in the treatment of ulcers in the studies of Murray et al. (1996), Murray and Grodinsky (1992) and Sanchez et al. (1998). In another article from Picavet (2002), however, is stated that scientific evidence for the enhancement of ulcer healing in horses regarding these agents is lacking. The reason for these differences in recording the efficiency of these receptors could be that their degree and duration of acid suppression varies among horses. (Bech et al. 1986, Furr et al. 1989)
Sucralfate, which are aluminium hydroxide and sucrose octasulfate, forming a sort of gel at a stomach pH lower than 4. (Picavet 2002) This gel is binding to the stomach walls and enhances mucus bicarbonate, local prostaglandin production and local blood flow (all protective factors). Moreover, it binds and concentrates epidermal growth factor (protective factor) and inhibits pepsin (inciting factor). (McCarthy 1991) Nevertheless, it is not proven to heal gastric ulcers but it can additionally be used in treatments with ranitidine. (Murray 2003)
By contrast, proton pump inhibitors seem to be a miracle cure. In the parietal cells where stomach acid is produced, hydrogen ion pumps are playing an important role in gastric acid production as they secret the hydrogen to form hydrochlorid acid (HCL). (Marqués 2007) This pump is an enzyme called the hydrogen (H+)- potassium(K+) adenosine triphosphatase. Inhibitors for this pump are lansoprazole and omeprazole. The latter, is a commonly used treatment for gastric ulcers as it has shown in a lot of studies to be effective regarding the healing of gastric ulcers and the prevention of their reoccurrence. It is applied orally and takes about 3-5 days till it starts to act on the secretion of acid. (Picavet 2002) It is moreover easy to use as it only needs to be given every 24 hours to the horse whereas others like sucralfate and histamine type 2 receptor antagonists need to be given every 6 – 8 hours. Moreover, these agents need to be given at a higher dose (Histamine 2 receptor antagonists: 6.6 mg/kg; sucralfate: 20 mg/kg) than omeprazole (4mg/kg). (Murray 2003)
It should be taken in to consideration, when using omeprazole that compound forms of this agent seem to be ineffective as it is in this form inactivated. (Andrews 2005)
Omeprazole can be used for treatment (4 mg/kg of body weight), for prevention of reoccurrence (2 mg/kg of body weight) and prevention of ulcers (1 mg/kg of body weight) (Andrews 2005; Andrews et al. 1999) and that without any side effects occurring.
Nevertheless, having the thought in mind that there is a product on the market accessible and proved to be effective regarding the healing and the prevention of EGUS it should not let those who are concerned forget, that the original causes of the disease must be treated!
References:
Andrews FM (2005), “Ulcers in the Stomach and Colon; Diagnosis and Treatment: A Pain in the Gut!” American Association of Equine Practitioners – AAEP –
Focus Meeting, 2005 – Québec, QC, Canada; available from www.ivis.org
Andrew FM, Bernard WV, Byars TD (1999), “Recommendations for the diagnosis and treatment of equine gastric ulcer syndrome (EGUS)”, Equine Vet. Educ.;
1: pp. 122-134
Bech JL, Byars TD (1986) “Gastroduodenal ulceration in foals”, Equine Vet J; 18(4): pp. 307-312.
Furr MO, Murray MJ (1989), “Treatment of gastric ulcers in horses with histamine
type 2 receptor antagonists”, Equine Vet J Suppl; 7: pp. 77-79.
Hammond CJ, Mason DK, Watkins KL, (1986), “Gastric ulceration in mature Thoroughbred horses”, Equine Vet J. 18: pp. 284-287
Marqués FJ (2007), “Equine Gastric Ulcer Syndrome”, Large Animal Veterinary Rounds; 7; 3, University of Saskatchewan
McCarthy DM (1991) “Sucralfate”, N Engl J Med; 325: pp. 1017-1025.
Mertz HR, Walsh JH (1991), “Peptic ulcer pathophysiology”, Med Clin North Am; 75: pp. 799-814.
Murray MJ (1997), “Gastroduodendal ulceration”, In: “Current therapy in Equine Medicine”, 4th ed., Ed: N.E. Robinson: pp. 191-197
Murray MJ, Grodinsky C (1989), “Regional Gastric pH measurements in horses and foals”, Equine Vet Suppl.: pp. 73-76
Murray MJ, Grodinsky C (1992), “The effects of famotidine, ranitidine, and magnesium hydroxide on gastric fluid pH in adult horses”, Equine Vet. J., Suppl 11: pp. 52-55
Murray MJ, Schusser GF, Pipers FS, Gross SJ (1996), “Factors associated with gastric lesions in Thoroughbred racehorses”, Equine Vet J.; 28: pp. 368-374
Murray MJ (2003), “Gastroduodenal Ulceration in Foals. In: 8ème Congrès de médecine et chirurgie équine – 8. Kongress für Pferdemedezin und -chirurgie – 8th
Congress on Equine Medicine and Surgery 2003, P. Chuit, A. Kuffer and S. Montavon (Eds.) Publisher: International Veterinary Information Service (www.ivis.org), Ithaca, New York, USA. [online] (cited May 5th, 2007) Available from: www.ivis.org
Nappert G, Vrins A, Larybyere M (1989), “Gastroduodenal ulceration in foals”, Compend Cont Educ Pract Vet; 11: pp. 345.
Picavet M-Th (2002), “Equine Gastric Ulcer Syndrome”, Proceedings of the First European Equine Nutrition & Health Congress, Feb. 9, 2002 – Antwerp Zoo,
Belgium. [online] (cited May 8th, 2007) Available from: http://www.ivis.org
Sanchez LC, Lester GD, Merritt AM (1998), “Effect of ranitidine on intragastric pH in clinically normal neonatal foals”, J Am Vet Med Assoc.; 212: pp. 1407-1412
Wikipedia (2007) “Omeprazole” [online]. Available from: http://en.wikipedia.org/wiki/Omeprazole [accessed 25 May 2007]
Edited by MOTIVATED 2015-10-07 4:59 PM
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Don't Wanna Make This Awkward
Posts: 3106
Location: Texas | runaround - 2015-10-07 3:23 PM Omeprazole takes days to work and needs to be fed consistently, but will heal ulcers. It's worthless if you're just giving it as a pre race "boost". Ranitidine will block acid within a few hours.
I am feeding the omeprazole everyday to treat the ulcers.
So could I buy Ranitidine from walmart to give berfore runs to offer some extra relief? | |
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Location: Big Blue Skies | Ranitidine is generic Tagamet. My vet still prescribes it as a cheaper alternative to omeprazole. You can give it on the day of race with aloe Vera. ive heard of people giving their horses Tums to soothe their stomach as well. | |
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Expert
Posts: 1525
| outrundaizy - 2015-10-07 5:32 PM runaround - 2015-10-07 3:23 PM Omeprazole takes days to work and needs to be fed consistently, but will heal ulcers. It's worthless if you're just giving it as a pre race "boost". Ranitidine will block acid within a few hours. I am feeding the omeprazole everyday to treat the ulcers.
So could I buy Ranitidine from walmart to give berfore runs to offer some extra relief?
yes. | |
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  Whack and Roll
Posts: 6342
Location: NE Texas | If you're feeding omeprazole daily and will continue through this weekend, you shouldn't need anything else. Once off the omeprazole, I would use Cur-OST Stomach for maintenance or Total Support for entire support. I would also encourage you to remove any processed feed, as it's proven to increase the inflammation in the hind gut, so you end up treating issues that processed feed is contributing to. | |
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I hate cooking and cleaning
Posts: 3310
Location: Jersey Girl | kboltwkreations - 2015-10-07 2:45 PM fulltiltfilly - 2015-10-07 1:43 PM Jailbreak. Can you tell me your experience with Jailbreak? I used it this past weekend for my gelding just to settle his stomach, and Im not sure if I gave it too far out or if I needed a follow up dose, but he got nutty on me..
I give it right before loading on the trailer. I don't usually give it again unless I am at a weekend race and he doesn't want to settle in. | |
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Expert
Posts: 1525
| fulltiltfilly - 2015-10-08 9:16 AM kboltwkreations - 2015-10-07 2:45 PM fulltiltfilly - 2015-10-07 1:43 PM Jailbreak. Can you tell me your experience with Jailbreak? I used it this past weekend for my gelding just to settle his stomach, and Im not sure if I gave it too far out or if I needed a follow up dose, but he got nutty on me..
What is Jailbreak? | |
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Extreme Veteran
Posts: 585
Location: Texas | I give 60cc of Maalox, generic is fine. I have found they like the mint and not the cherry. Give it before you get on to warm up. Works great for me. I also keep a hay bag in front of them all the time I'm at the barrel race.
Edited by workerbee 2015-10-08 9:44 AM
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Elite Veteran
Posts: 1037
| MOTIVATED - 2015-10-08 9:25 AM
fulltiltfilly - 2015-10-08 9:16 AM kboltwkreations - 2015-10-07 2:45 PM fulltiltfilly - 2015-10-07 1:43 PM Jailbreak. Can you tell me your experience with Jailbreak? I used it this past weekend for my gelding just to settle his stomach, and Im not sure if I gave it too far out or if I needed a follow up dose, but he got nutty on me..
Jailbreak by Oxygen
Pre-race paste for the nervous horse, horses with ulcers, and gate issues. Contains probiotics, electrolytes and an acid reducer. | |
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 Extreme Veteran
Posts: 396
Location: Iowa | Equi-Sure....lots of girls around the midwest run on it and thier horses have sure improved.
http://equi-sure.com/ | |
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 Jr. Detective
Location: Beggs, OK | Herbie - 2015-10-08 9:06 AM If you're feeding omeprazole daily and will continue through this weekend, you shouldn't need anything else. Once off the omeprazole, I would use Cur-OST Stomach for maintenance or Total Support for entire support. I would also encourage you to remove any processed feed, as it's proven to increase the inflammation in the hind gut, so you end up treating issues that processed feed is contributing to. Omeprazole also blocks the absorption of important vitamins and minerals, which will ultimately lead to deficiencies. Daily Omeprazole has always seemed like a really bad idea to me, why not figure out the source of the stress, anxiety, or pain that is causing the ulcers? I have found 100% of the issues that I was dealing with to be nutritional....my Gastrogard bill has gone to ZERO.
As a person who has dealt with ulcers since childhood, I have found that I no longer have flare-ups since I have learned to deal with them through how, what, and when I eat.
Edited by rachellyn80 2015-10-08 10:12 AM
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 Elite Veteran
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Location: Sunny So Cal | Raniditine | |
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What do you give on race days for ulcers?