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Adequan vs pentosan vs polyglycan
emricmacy
Reg. Sep 2016
Posted 2018-05-07 4:54 PM
Subject: Adequan vs pentosan vs polyglycan


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What is the best for a horse with moderate arthritis? I asked a few different vets about adequan. I gave the loading dose in October, and I do one a month shots now, and I can't really tell if it's doing anything. The few vets I asked said to keep doing the adequan once a month. I'm not saying they are wrong, I just don't see a big difference.
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FLITASTIC
Reg. Jun 2012
Posted 2018-05-07 6:04 PM
Subject: RE: Adequan vs pentosan vs polyglycan



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Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.
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emricmacy
Reg. Sep 2016
Posted 2018-05-07 6:21 PM
Subject: RE: Adequan vs pentosan vs polyglycan


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FLITASTIC - 2018-05-07 6:04 PM

Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.

We have arthritis issues already. I just don't notice a difference with once a month adequan. Both vets I talked to said they do not recommend doing another loading dose of adequan, that the once a month is good. Is pentosan prescription only? How often do you give?
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I<3BarrelRacing
Reg. Jan 2010
Posted 2018-05-07 6:34 PM
Subject: RE: Adequan vs pentosan vs polyglycan




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Pentosan is prescribed, it’s once a week for 4 weeks for the loading dose and then once a month after that. I asked my vet her thoughts on adequan vs pentosan when my mare was diagnosed with the very beginning stages of hock arthritis a couple months ago and she was saying for a while they could not get adequan and had to use pentosan instead and after using it on the horses that had been using adaquan previously they noticed more of an improvement with the pentosan so they decided to keep using the pentosan. Have heard people on here though say that it tends to thin the blood so not to give it a couple of days before a race in case they bleed

Edited by I<3BarrelRacing 2018-05-07 6:35 PM
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emricmacy
Reg. Sep 2016
Posted 2018-05-07 6:53 PM
Subject: RE: Adequan vs pentosan vs polyglycan


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I<3BarrelRacing - 2018-05-07 6:34 PM

Pentosan is prescribed, it’s once a week for 4 weeks for the loading dose and then once a month after that. I asked my vet her thoughts on adequan vs pentosan when my mare was diagnosed with the very beginning stages of hock arthritis a couple months ago and she was saying for a while they could not get adequan and had to use pentosan instead and after using it on the horses that had been using adaquan previously they noticed more of an improvement with the pentosan so they decided to keep using the pentosan. Have heard people on here though say that it tends to thin the blood so not to give it a couple of days before a race in case they bleed

I would like to try it for my gelding, but for some reason my vet doesn't think it's better than adequan once a month.
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FLITASTIC
Reg. Jun 2012
Posted 2018-05-07 7:59 PM
Subject: RE: Adequan vs pentosan vs polyglycan



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emricmacy - 2018-05-07 4:21 PM

FLITASTIC - 2018-05-07 6:04 PM

Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.

We have arthritis issues already. I just don't notice a difference with once a month adequan. Both vets I talked to said they do not recommend doing another loading dose of adequan, that the once a month is good. Is pentosan prescription only? How often do you give?

Those vets need to do some research from Luitpold. Lol. That USED to be the protocol, load series plus monthly. Now the company recommends 2 full loading doses a year and Nothing monthly. It has been proven the monthly adequan does NOt provide any additional benefit.
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dRowe
Reg. Jan 2017
Posted 2018-05-07 8:08 PM
Subject: RE: Adequan vs pentosan vs polyglycan



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FLITASTIC - 2018-05-07 8:59 PM

emricmacy - 2018-05-07 4:21 PM

FLITASTIC - 2018-05-07 6:04 PM

Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.

We have arthritis issues already. I just don't notice a difference with once a month adequan. Both vets I talked to said they do not recommend doing another loading dose of adequan, that the once a month is good. Is pentosan prescription only? How often do you give?

Those vets need to do some research from Luitpold. Lol. That USED to be the protocol, load series plus monthly. Now the company recommends 2 full loading doses a year and Nothing monthly. It has been proven the monthly adequan does NOt provide any additional benefit.

Good to know because I know NOTHING about adequan. Vet recommended because my horse got jock injections with previous owner. I’ve had him 1.5 years and we just did a full lameness and there’s no need for injections. So we’re doing 7 doses of adequan every 4 days and will re-evaluate in 6 months. Nothing was mentioned about monthly injections after these.
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horsegirl
Reg. Feb 2004
Posted 2018-05-08 7:39 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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I only have experience with Pentosan and I am a fan of it. As my vet explained, it is better for horses with visible issues already. I did a loading dose for 4 weeks (once a week) and then monthly after that, but he said I could even do bi-weekly. I did feel results.
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Mainer-racer
Reg. Oct 2004
Posted 2018-05-08 8:22 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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LOVE LOVE the poly! I have a 5, 16 and 29 year old on it.  PLUS just added it for my 2 dogs and see a HUGE difference!
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emricmacy
Reg. Sep 2016
Posted 2018-05-08 8:42 AM
Subject: RE: Adequan vs pentosan vs polyglycan


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I want to start the Pentosan. Do I ask my vet for a prescription? I see racehorsemeds.com has Pentosan for $149.95. horseprerace.com also has it.
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horsegirl
Reg. Feb 2004
Posted 2018-05-08 9:14 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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You could order it anywhere if your vet can't give it to you through their supplier. Yes, though, it does require an Rx. Just like any med, however, you can order anywhere. Make sure the concentration is high. A weaker concentration would cost less, but also be less effective. I used 250mg/mL and I had a 50mL bottle, if I recall. It lasted about 4-5 months with loading dose and then biweekly or monthly as needed.
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HarlanLivesOn
Reg. May 2009
Posted 2018-05-08 9:25 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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emricmacy - 2018-05-08 7:42 AM

I want to start the Pentosan. Do I ask my vet for a prescription? I see racehorsemeds.com has Pentosan for $149.95. horseprerace.com also has it.

I've always gotten Pentosan through horseprerace and have never had any complaints.
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daisycake123
Reg. Dec 2006
Posted 2018-05-08 9:26 AM
Subject: RE: Adequan vs pentosan vs polyglycan


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its been a while but someone on here had printed a study that pentosan was the best for arthritis.
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emricmacy
Reg. Sep 2016
Posted 2018-05-08 9:45 AM
Subject: RE: Adequan vs pentosan vs polyglycan


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horsegirl - 2018-05-08 9:14 AM

You could order it anywhere if your vet can't give it to you through their supplier. Yes, though, it does require an Rx. Just like any med, however, you can order anywhere. Make sure the concentration is high. A weaker concentration would cost less, but also be less effective. I used 250mg/mL and I had a 50mL bottle, if I recall. It lasted about 4-5 months with loading dose and then biweekly or monthly as needed.

Where did you get it from?
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horsegirl
Reg. Feb 2004
Posted 2018-05-08 9:47 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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My vet.  They (should) have a pharmacy supplier to keep their truck stocked up on most things. If not, their supplier (should) get it for them.

Edited by horsegirl 2018-05-08 9:48 AM
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r_beau
Reg. Apr 2010
Posted 2018-05-08 4:18 PM
Subject: RE: Adequan vs pentosan vs polyglycan



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FLITASTIC - 2018-05-07 7:59 PM
emricmacy - 2018-05-07 4:21 PM
FLITASTIC - 2018-05-07 6:04 PM Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.
We have arthritis issues already. I just don't notice a difference with once a month adequan. Both vets I talked to said they do not recommend doing another loading dose of adequan, that the once a month is good. Is pentosan prescription only? How often do you give?
Those vets need to do some research from Luitpold. Lol. That USED to be the protocol, load series plus monthly. Now the company recommends 2 full loading doses a year and Nothing monthly. It has been proven the monthly adequan does NOt provide any additional benefit.
 Well, Luitpold Animal Health / Luitpold Pharmaceuticals owns Adequan, so I'm always skeptical of any company that does their own research. Not to mention, their own information right on their website and in their PDFs say "clinical significance of these results is unknown" when they talk about the levels of measured hyaluronic acid. Probably because the Burba study they reference found no statistical significant between the tested joint and the control joint. (Not to mention the study is from 1993 and there was a small sample size of 8 horses, but I digress.)

The Burba study showed that Adequan did not stay in the system beyond 96 hours; which is probably where they came up with the dosing schedule of every 4 days when doing the loading dose. But their study does not COMPARE two loading doses a year to a once-a-month maintenance doses.  That has not actually been studied. At least not that I can find.

Can you provide links otherwise? Because I'm not seeing the proof.

I don't even see anything in their study of why they came up with 7 doses. Why 7 doses? I understand where they come up with every 4 days. That makes sense. But what's stopping a perso n (besides cost) from giving Adequan every 4 days all year long? Why stop at 7 doses? In their brochure, they "reference" something where 36 horses were testing with the 7 doses, but their link at the end of the brochure doesn't work. A little digging on the FDA website says that these Freedom of Information Summaries are not available electronically. A little more googling found someone who copy/pasted some of the study (but not the actual study itself) where this "study" in question was comparing different amounts to placebo. But regardless, they did not do monthly doses and did not compare to monthly doses. So I don't see how that particular study would PROVE that monthly doesn't work.

So again, if I'm missing something, let me know. But I don't see the proof.

**Let me add a disclaimed that I have indeed tried Adequan for one of my horses. Can't say I noticed much difference at all for him, individually.



 

Edited by r_beau 2018-05-08 4:38 PM
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Fancie_That_Chrome_
Reg. Mar 2012
Posted 2018-05-09 2:02 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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Polyglycan hands down.... I use it on my working horses my horses in training, AND the 28 year old stud that i stand... When he gets up to my place in the spring i give him that and holy SMOKES totally different horse! Runs, hops, bucks, frisky as anything.... I'm a SOLID believer in it. Poly has never let me down
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MOGirl07
Reg. Feb 2012
Posted 2018-05-09 8:06 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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Mainer-racer - 2018-05-08 8:22 AM

LOVE LOVE the poly! I have a 5, 16 and 29 year old on it.  PLUS just added it for my 2 dogs and see a HUGE difference!

Curious how often they require shots/if they require injections less often?
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Mainer-racer
Reg. Oct 2004
Posted 2018-05-09 8:12 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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The 5 Year old gets a shot every 3 months, the 29 year old gets a shot in April and than one in October, the 16 year old gets one April, June, August and October.  They are all on MSM and Equithrive. 
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TheDutchMan01
Reg. Jan 2010
Posted 2018-05-09 8:53 AM
Subject: RE: Adequan vs pentosan vs polyglycan


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I just started my 17 yr old on Pentosan and wow hes working great! He also got a shot of osphos but the vet said it would take 3 weeks to work and I ran him after 2 weeks and he worked better than he has in a long time. So I guess its hard to really determine which has helped but I plan to keep him on the Pentosan. I don't think I am going to do anymore osphos because I don't like the side effects (that's a whole other topic). I feel like Pentosan is more affordable than adequan.
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Dreamingofcans
Reg. Jan 2011
Posted 2018-05-09 9:25 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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FLITASTIC - 2018-05-07 6:04 PM

Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.

How often do you give the pentosan?
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Dreamingofcans
Reg. Jan 2011
Posted 2018-05-09 9:25 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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Mainer-racer - 2018-05-08 8:22 AM

LOVE LOVE the poly! I have a 5, 16 and 29 year old on it.  PLUS just added it for my 2 dogs and see a HUGE difference!

How are you giving the poly?
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FLITASTIC
Reg. Jun 2012
Posted 2018-05-09 10:03 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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Dreamingofcans - 2018-05-09 7:25 AM

FLITASTIC - 2018-05-07 6:04 PM

Pentosan is a little better for horses with arthritis issues already. I like adequan for young healthy joints that you want to keep that way. Poly is a great option and i use it few days before long weekends.

How often do you give the pentosan?

Pentosan monthly after 4 week loading dose. I give Poly monthly for a horse with no issues or every 2 weeks for a horse with issues.
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RHRanch
Reg. Sep 2004
Posted 2018-05-10 9:09 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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For you Poly users... I have heard it could cause a horse to bleed.  Is this true?   
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RHRanch
Reg. Sep 2004
Posted 2018-05-10 10:11 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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For you Poly users... I have heard it could cause a horse to bleed.  Is this true?   
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FLITASTIC
Reg. Jun 2012
Posted 2018-05-10 10:37 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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RHRanch - 2018-05-10 8:11 AM

For you Poly users... I have heard it could cause a horse to bleed.  Is this true?   

Nope, never heard of that. THe ingredients in Poly ( HA, Glucosamine, chondroiton) are in a million products OTC, IV etc. Never heard that. Now pentosan won't CAUSE them to bleed but may make them bleed worse if they DO bleed. It is an anticoagulant.
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Mainer-racer
Reg. Oct 2004
Posted 2018-05-11 9:44 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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Dreamingofcans - 2018-05-09 10:25 AM
Mainer-racer - 2018-05-08 8:22 AM LOVE LOVE the poly! I have a 5, 16 and 29 year old on it.  PLUS just added it for my 2 dogs and see a HUGE difference!
How are you giving the poly?

IV
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Mainer-racer
Reg. Oct 2004
Posted 2018-05-11 9:45 AM
Subject: RE: Adequan vs pentosan vs polyglycan



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RHRanch - 2018-05-10 11:11 AM For you Poly users... I have heard it could cause a horse to bleed.  Is this true?   

Never had that problem, nor have I heard of that before. A lot of horse are on it up in my area and no bleeders.
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MOGirl07
Reg. Feb 2012
Posted 2018-05-11 2:19 PM
Subject: RE: Adequan vs pentosan vs polyglycan



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Mainer-racer - 2018-05-11 9:45 AM

RHRanch - 2018-05-10 11:11 AM For you Poly users... I have heard it could cause a horse to bleed.  Is this true?   

Never had that problem, nor have I heard of that before. A lot of horse are on it up in my area and no bleeders.

I haven't had any issues with this either. My mare has been on it for about 18 mos now.
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Fancie_That_Chrome_
Reg. Mar 2012
Posted 2018-05-12 6:05 PM
Subject: RE: Adequan vs pentosan vs polyglycan



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Mainer-racer - 2018-05-11 8:45 AM

RHRanch - 2018-05-10 11:11 AM For you Poly users... I have heard it could cause a horse to bleed.  Is this true?   

Never had that problem, nor have I heard of that before. A lot of horse are on it up in my area and no bleeders.

I do IV or IM. If the horse is a little pain in the A** IM if they are easy IV. I dont think ive ever noticed better or worse results from either or
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