|
|
Extreme Veteran
Posts: 560
 
Location: Where the buffalo roam | It is the MDR1 gene and any dog that has it is sensitive to a multitude of drugs. Collies have the highest percentage followed by Australian Shepherds. It affects how the drug is handled in the system. Instead of being absorbed gradually, dogs with this gene absorb it all at once. The drugs on the list have to either be avoided or given in MUCH smaller doses. Mini aussies are affected the same as standards. If you Google it, you can find a link to the list on the Washington State University site. I had a mini with the gene and it affected how his chemo drug was given. I always pickup all ivermectin off the ground after worming because of this. I highly recommend getting the test - it is not very expensive and takes very little time to get the results.
Here is the link: http://www.vetmed.wsu.edu/depts-vcpl/
Edited by Nobody 2015-04-01 2:12 PM
|
|
| |
|
 I Prefer to Live in Fantasy Land
Posts: 64864
  
Location: In the Hills of Texas | sorrel horse ranch - 2015-04-01 10:00 AM I know what I do is a no no. I worm my dogs with the cattle wormer Ivermectin. I have never had a problem with any of my dogs including my Border Collies. I had a friend give it to his Heeler and he did the same thing your Aussie is doing. He regained his sight after 3 days. I guess the main thing is how much did your dog injest. Hopefully he will be okay in a few days. I hope so for your son.
We also worm our dogs with the cattle ivomec and have been doing so for at least 25 years.
We had a friend with an Australian Shepherd and he regained most of his sight. Can't remember the details as it was a long time ago.
Sending positive thoughts for a good outcome. |
|
| |
|
 Expert
Posts: 2457
| Whiteboy - 2015-04-01 9:49 AM So I went out this morning to take my dog (a 4 year old Australian Shepherd) outside. And that sucker is blind as a bat, his pupils are huge and he's bumping into everything and doesn't hardley dare take a step. Take him to the vet right away. My 2 year old son adores this dog. The vet, agrees that the dog is blind but hasn't got a clue why. We get on the phone with an animal eye doctor and she finally asks if I have any horses and if they have been wormed in the last 3 days with Ivermectin. Which I did last night. Apparantly the dog must have licked up a little that fell on the ground, and is now likely permanantly blind. Anybody else ever had this happen, and did the dog regain any sight?
YES!!
Border Collies are also incredibly sensitive to Ivermectin. We had one that when we wormed horses, he walked through the "extra spit out stuff" and got it on his paws ... next day same deal. The vets treated him and kept him at K State Vet Med for a few days - he regained his sight.
I'm not sure what they use to treat it or how quickly you have to catch it to be successful.
I do know that herding dogs are very suceptible to this!
|
|
| |
|
Expert
Posts: 2457
| Nevertooold - 2015-04-01 2:59 PM sorrel horse ranch - 2015-04-01 10:00 AM I know what I do is a no no. I worm my dogs with the cattle wormer Ivermectin. I have never had a problem with any of my dogs including my Border Collies. I had a friend give it to his Heeler and he did the same thing your Aussie is doing. He regained his sight after 3 days. I guess the main thing is how much did your dog injest. Hopefully he will be okay in a few days. I hope so for your son. We also worm our dogs with the cattle ivomec and have been doing so for at least 25 years.
We had a friend with an Australian Shepherd and he regained most of his sight. Can't remember the details as it was a long time ago.
Sending positive thoughts for a good outcome.
The working doses/ working dilution of wormer are different between between species - which is why they are labeled differently. As I recall, cattle Ivermectin is a lower dilution than the horse wormer ... I will do some digging on that or someone please correct me .... |
|
| |
|
 Member
Posts: 49
| My little jack russell/fiest did the same exact thing. We took her to the vet, not sure what the vet did but she was fine a day or 2 later. |
|
| |
|
 A Somebody to Everybody
Posts: 41354
Location: Under The Big Sky Of Texas | Holy cow, never heard of this, prayers for your poor dog. |
|
| |
|
I Prefer to Live in Fantasy Land
Posts: 64864
Location: In the Hills of Texas | lindseylou2290 - 2015-04-01 3:10 PM Nevertooold - 2015-04-01 2:59 PM sorrel horse ranch - 2015-04-01 10:00 AM I know what I do is a no no. I worm my dogs with the cattle wormer Ivermectin. I have never had a problem with any of my dogs including my Border Collies. I had a friend give it to his Heeler and he did the same thing your Aussie is doing. He regained his sight after 3 days. I guess the main thing is how much did your dog injest. Hopefully he will be okay in a few days. I hope so for your son. We also worm our dogs with the cattle ivomec and have been doing so for at least 25 years.
We had a friend with an Australian Shepherd and he regained most of his sight. Can't remember the details as it was a long time ago.
Sending positive thoughts for a good outcome.
I had a vet tell me what to use and how much and that is all I know besides not using the Cattle Ivomec that takes care of Liver flukes. |
|
| |
|
 Cute Little Imp
Posts: 2747
Location: N Texas | lindseylou2290 - 2015-04-01 3:10 PM
Nevertooold - 2015-04-01 2:59 PM sorrel horse ranch - 2015-04-01 10:00 AM I know what I do is a no no. I worm my dogs with the cattle wormer Ivermectin. I have never had a problem with any of my dogs including my Border Collies. I had a friend give it to his Heeler and he did the same thing your Aussie is doing. He regained his sight after 3 days. I guess the main thing is how much did your dog injest. Hopefully he will be okay in a few days. I hope so for your son. We also worm our dogs with the cattle ivomec and have been doing so for at least 25 years.
We had a friend with an Australian Shepherd and he regained most of his sight. Can't remember the details as it was a long time ago.
Sending positive thoughts for a good outcome.
I did a bunch of research and found the cattle wormer is too strong for dogs and must be diluted first. The sheep drench is already diluted to a safe level, so that's what I give my dogs. The chihuahua gets one drop and the bigger dogs get three drops. |
|
| |
|
 Expert
Posts: 4121
Location: SE Louisiana | I remember when Ivermectin first came into use for livestock and it was known then to be dangerous to collie type dogs. Mom always had a sheltie as her shadow and she was very careful with it. |
|
| |
|
 Take a Picture
Posts: 12838
| I taught with a lady that had her masters degree in equine parasitology and also raised standard Australian Shepherds. She told me to be very careful about using Ivermectin. She said to remember------ four white feet, don't treat. I really watch what falls on the ground and where I throw the tubes or syringes.
|
|
| |
|
Holy Fruit Loops!
Posts: 1708
Location: Colorado | Whiteboy - 2015-04-01 9:49 AM So I went out this morning to take my dog (a 4 year old Australian Shepherd) outside. And that sucker is blind as a bat, his pupils are huge and he's bumping into everything and doesn't hardley dare take a step. Take him to the vet right away. My 2 year old son adores this dog. The vet, agrees that the dog is blind but hasn't got a clue why. We get on the phone with an animal eye doctor and she finally asks if I have any horses and if they have been wormed in the last 3 days with Ivermectin. Which I did last night. Apparantly the dog must have licked up a little that fell on the ground, and is now likely permanantly blind. Anybody else ever had this happen, and did the dog regain any sight?
Whiteboy,
I would suggest looking up the MDR1 Gene mutation. Take a list of ALL the drugs that can be an issue to your vet. Although Ivermectrin is the best known there are several other drugs that can be an issue. Since your dog reacted this time you need to be very careful about this in the future.
Blind or not this dog and your two year old will be fine. A dog and his boy can adapt to just about anything.
Paws crossed for a good outcome.
karen
|
|
| |
|
Holy Fruit Loops!
Posts: 1708
Location: Colorado | Gunner11 - 2015-04-01 8:42 PM lindseylou2290 - 2015-04-01 3:10 PM Nevertooold - 2015-04-01 2:59 PM sorrel horse ranch - 2015-04-01 10:00 AM I know what I do is a no no. I worm my dogs with the cattle wormer Ivermectin. I have never had a problem with any of my dogs including my Border Collies. I had a friend give it to his Heeler and he did the same thing your Aussie is doing. He regained his sight after 3 days. I guess the main thing is how much did your dog injest. Hopefully he will be okay in a few days. I hope so for your son. We also worm our dogs with the cattle ivomec and have been doing so for at least 25 years.
We had a friend with an Australian Shepherd and he regained most of his sight. Can't remember the details as it was a long time ago.
Sending positive thoughts for a good outcome. I did a bunch of research and found the cattle wormer is too strong for dogs and must be diluted first. The sheep drench is already diluted to a safe level, so that's what I give my dogs. The chihuahua gets one drop and the bigger dogs get three drops.
This is specific to Collies, Aussies, BC's, etc..
If a dog has the MDR1 mutated gene it does NOT matter what ivermec you use. PLEASE understand this is a genetics issue not a dosing issue. And Ivermec is not the only drug that can be an issue.
The Australian Shepherd club of America spent a lot of years and money on genetic research to find this. A simple check swab is available.
For those of you who say we have used cattle ivermec for ever, blah, blah, blah.....
Not all dogs will show the same symptoms immediately, some build for years and mainfest in other ways than eye issues.
If you value your dogs PLEASE do not brush this off. Look it up and print a list of drugs that can become an issue. Give that list to your Vet. It could save your dogs life!
karen |
|
| |
|
Location: Texas | My good friend lost both of her Border Collies because they ingested too much Ivermectin. Her husband didn't realize it was harmful to them and never thought twice when he gave it to them, she also had no idea it was harmful. She found them the next morning, less than 12hrs later. |
|
| |
|
  Warmblood with Wings
Posts: 27846
Location: Florida.. | any updates |
|
| |
|
 That's White "Man" to You
Posts: 5515
| Still blind, went off food today. Still hoping for a recovery. |
|
| |
|
Warmblood with Wings
Posts: 27846
Location: Florida.. | praying for a full recovery |
|
| |
|
 My Heart Be Happy
Posts: 9159
Location: Arkansas | Praying he makes a complete and quick recovery |
|
| |
|
A Somebody to Everybody
Posts: 41354
Location: Under The Big Sky Of Texas | Whiteboy - 2015-04-02 10:13 PM Still blind, went off food today. Still hoping for a recovery.
Oh no, I hope that he get's better, poor fella. Prayers |
|
| |
Folks on-line