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your favorite Ulcer treatment is......?

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FlyingJT
Reg. Jan 2014
Posted 2015-05-07 8:01 PM
Subject: RE: your favorite Ulcer treatment is......?



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RoaniePonie11 - 2015-05-07 7:05 PM

Daily ranitidine users:

How much are you giving??

The drug book at work said 3.3mg/kg every 8 hours or 6.6mg/kg every 12 hours (those are off the top of my head but should be close). That seems like a lot of pills to get a horse to eat twice a day on a daily basis. For a 1200# horse that's roughly 11 tabs twice a day.

Y'all weigh in :)

10 -300mg tablets, am & pm
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barrel racing addict
Reg. Jul 2014
Posted 2015-05-07 8:31 PM
Subject: RE: your favorite Ulcer treatment is......?


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I have a horse that has ulcers really bad. We did 28 days of Gastrogard, a half a tube a day along with Neigh-Lox Advanced. When he finishes the Gastrogard, he will be on the Neigh-Lox the rest of his life but soooo well worth it.
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crossarrowk
Reg. Dec 2007
Posted 2015-05-07 8:52 PM
Subject: RE: your favorite Ulcer treatment is......?



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So can you give the ranitidine to "cure up" the ulcers and then follow up with probiotics, etc?  Thanks everyone! 
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total performance
Reg. Nov 2007
Posted 2015-05-07 9:02 PM
Subject: RE: your favorite Ulcer treatment is......?



Namesless in BHW


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Any horse that comes in our barn automatically goes on ulcer maintenance. 
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FlyingJT
Reg. Jan 2014
Posted 2015-05-07 10:42 PM
Subject: RE: your favorite Ulcer treatment is......?



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crossarrowk - 2015-05-07 8:52 PM

So can you give the ranitidine to "cure up" the ulcers and then follow up with probiotics, etc? ย Thanks everyone!ย 

Yes, i still will give horses that are very prone to them or nervous natured a dose anytime there is a change in routine or added stress.
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oija
Reg. Feb 2012
Posted 2015-05-08 8:55 AM
Subject: RE: your favorite Ulcer treatment is......?



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Ranitidine over a long time can allow time for ulcers to cure, but it takes much longer, which is why we use it more as a preventative, maintenance (they don't get it all the time, just when we know they will be stressed). If you know they have ulcers, I'd do 30 to 60 days on omeprazole and then switch them over to ranitidine. And it comes out to about 30 pills a feeding twice a day @ 150 mg a pill.
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Mainer-racer
Reg. Oct 2004
Posted 2015-05-08 9:04 AM
Subject: RE: your favorite Ulcer treatment is......?



Maine-iac


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I didn't fool around - 28 days of Gastrogard, now on Smart Pak Gut and aloe juice with Ulcer Gard before and after showing. I found this interesting:


Compounded omeprazole in treatment of equine gastric ulcers

A study of the University of California, Davis, evaluated the efficacy of compounded omeprazole purchased from a private U.S. pharmacy to Gastrogard®, an FDA-registered formulation of the drug manufactured by Merial Ltd. in 32 horses with gastric ulcers.

`The compounded omeprazole we evaluated was not equivalent to the FDA-approved formulation,` says lead investigator Jack Snyder, DVM, Ph.D., chief of equine lameness and surgery at UC Davis. `It did not effectively lower gastric ulcers scores or resolve gastric lesions.

`The bottom line is that veterinarians, trainers and horse owners need to be very careful when buying any product that is not regulated, because they might not be getting what they asked for,` adds Snyder.

The study used 32 thoroughbred horses that were examined with an endoscope and identified as having significant gastric ulceration.

Endoscopic examinations after 30 days and 60 days of treatment showed that compounded omeprazole neither significantly decreased ulcer severity scores nor aided in preventing the recurrence of ulcers, while Gastrogard was shown to be highly effective, according to researchers.

Of the horses treated first with Gastrogard for 30 days, endoscopic exams showed that all 16 horses had drastically reduced ulcer severity scores, Snyder reports. When those horses were treated with compounded product for the next 30 days, the ulcers returned.

Conversely, of the horses treated first with compounded omeprazole, endoscopic exams after 30 days of treatment showed the compounded product did not significantly reduce ulcer severity scores. When those horses were treated with Gastrogard for the remaining 30 days, all 16 horses had significantly reduced ulcer scores, researchers note.

 
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Just Bring It
Reg. Oct 2003
Posted 2015-05-08 9:19 AM
Subject: RE: your favorite Ulcer treatment is......?



Husband Spoiler


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Very affordable and well studied omeprazole. Ranitidine is available as well. http://www.equinerxsolutions.com
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hlynn
Reg. Dec 2011
Posted 2015-05-08 9:28 AM
Subject: RE: your favorite Ulcer treatment is......?


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I decided to go the GastroPLUS route on one I suspected to have ulcers. I didn't want to have to keep him on omeprazole the rest of his life. Everything I read said you have to keep up with it to keep them away.

So I did 32 doses of GastroPLUS. Now I have the ulcer prevent in his muscle mass. I'm not 100% sure he had ulcers, but he would walk away from his feed, crib constantly, and just looked miserable. He was also very thin when I got him. Now he's fat and happy. No longer walking away from feed. Eats all of it. And isn't cribbing nearly as much. Overall his attitude has very much improved.
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astreakinchic
Reg. Sep 2011
Posted 2015-05-08 9:34 AM
Subject: RE: your favorite Ulcer treatment is......?


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Mainer-racer - 2015-05-08 10:04 AM

I didn't fool around - 28 days of Gastrogard, now on Smart Pak Gut and aloe juice with Ulcer Gard before and after showing. I found this interesting:


Compounded omeprazole in treatment of equine gastric ulcers

A study of the University of California, Davis, evaluated the efficacy of compounded omeprazole purchased from a private U.S. pharmacy to Gastrogardยฎ, an FDA-registered formulation of the drug manufactured by Merial Ltd. in 32 horses with gastric ulcers.

`The compounded omeprazole we evaluated was not equivalent to the FDA-approved formulation,` says lead investigator Jack Snyder, DVM, Ph.D., chief of equine lameness and surgery at UC Davis. `It did not effectively lower gastric ulcers scores or resolve gastric lesions.

`The bottom line is that veterinarians, trainers and horse owners need to be very careful when buying any product that is not regulated, because they might not be getting what they asked for,` adds Snyder.

The study used 32 thoroughbred horses that were examined with an endoscope and identified as having significant gastric ulceration.

Endoscopic examinations after 30 days and 60 days of treatment showed that compounded omeprazole neither significantly decreased ulcer severity scores nor aided in preventing the recurrence of ulcers, while Gastrogard was shown to be highly effective, according to researchers.

Of the horses treated first with Gastrogard for 30 days, endoscopic exams showed that all 16 horses had drastically reduced ulcer severity scores, Snyder reports. When those horses were treated with compounded product for the next 30 days, the ulcers returned.

Conversely, of the horses treated first with compounded omeprazole, endoscopic exams after 30 days of treatment showed the compounded product did not significantly reduce ulcer severity scores. When those horses were treated with Gastrogard for the remaining 30 days, all 16 horses had significantly reduced ulcer scores, researchers note.

ย 

This study was completely MERIAL funded. They did not release the brands/compounding pharmacy used. It is suspected from ppl who have talked with Dr. Snyder that they didn't even use the buffered omeprazole just like plain powder or paste omeprazole. Sneaky sneaky Merial.
ETA: I've used some that I thought was a waste of my money. But Precision pharmacy has always given us results on ulcer horses, so far. I better knock on wood now LOL

Edited by astreakinchic 2015-05-08 9:42 AM
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AngieM1
Reg. Aug 2012
Posted 2015-05-08 10:23 AM
Subject: RE: your favorite Ulcer treatment is......?


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Posts: 242
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RoaniePonie11 - 2015-05-07 7:05 PM

Daily ranitidine users:

How much are you giving??

The drug book at work said 3.3mg/kg every 8 hours or 6.6mg/kg every 12 hours (those are off the top of my head but should be close). That seems like a lot of pills to get a horse to eat twice a day on a daily basis. For a 1200# horse that's roughly 11 tabs twice a day.

Y'all weigh in :)

I feed OTC Ranitidine BJs, Costco, Sams Club etc will have it, even most local Drugs stores. I feed 16 pills 2x a day for my Ulcer horses. It works out to be about 30$ a month that way, some horses (severe cases get 16 pills 3x a day) but it is cheaper to buy it this way I find exactly the same effectiveness as the Ranitidine from the Vet.

The OTC (people version pills) are 150 mg ea.
I also feed 1/3 cup pure aloe juice 2x a day. & 1 - 1.5 lb alfalfa pellets. Wet grain-pellets


My horse also eats better when on Formula 1 Noni.

Ranitidine doesn't shut the acid pump off completely like the omeprazole will do. Ranitidine is more of an AntiAcid. Which is less likely to cause colic. Ive gone over this thousands of time with numerous specialists and I find Ranitidine works more effectively and can be used for very extended periods of time without causing any harm.
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Griz
Reg. Sep 2003
Posted 2015-05-08 11:19 AM
Subject: RE: your favorite Ulcer treatment is......?


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wyoming barrel racer - 2015-05-07 2:33 PM

GastroPLUS for fore/hind gut. I have ugly pictures to prove how well this stuff works. 32 doses $115.95 if you order through meย 

I wish there was a way I could "share" this like on FB, so I could keep it for future reference, so I am posting on here instead so I can find it if I do a search!
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Mainer-racer
Reg. Oct 2004
Posted 2015-05-08 12:42 PM
Subject: RE: your favorite Ulcer treatment is......?



Maine-iac


Posts: 3334
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Location: Got Lobsta?
astreakinchic - 2015-05-08 10:34 AM
Mainer-racer - 2015-05-08 10:04 AM I didn't fool around - 28 days of Gastrogard, now on Smart Pak Gut and aloe juice with Ulcer Gard before and after showing. I found this interesting:





Compounded omeprazole in treatment of equine gastric ulcers



A study of the University of California, Davis, evaluated the efficacy of compounded omeprazole purchased from a private U.S. pharmacy to Gastrogard®, an FDA-registered formulation of the drug manufactured by Merial Ltd. in 32 horses with gastric ulcers.



`The compounded omeprazole we evaluated was not equivalent to the FDA-approved formulation,` says lead investigator Jack Snyder, DVM, Ph.D., chief of equine lameness and surgery at UC Davis. `It did not effectively lower gastric ulcers scores or resolve gastric lesions.



`The bottom line is that veterinarians, trainers and horse owners need to be very careful when buying any product that is not regulated, because they might not be getting what they asked for,` adds Snyder.



The study used 32 thoroughbred horses that were examined with an endoscope and identified as having significant gastric ulceration.



Endoscopic examinations after 30 days and 60 days of treatment showed that compounded omeprazole neither significantly decreased ulcer severity scores nor aided in preventing the recurrence of ulcers, while Gastrogard was shown to be highly effective, according to researchers.



Of the horses treated first with Gastrogard for 30 days, endoscopic exams showed that all 16 horses had drastically reduced ulcer severity scores, Snyder reports. When those horses were treated with compounded product for the next 30 days, the ulcers returned.



Conversely, of the horses treated first with compounded omeprazole, endoscopic exams after 30 days of treatment showed the compounded product did not significantly reduce ulcer severity scores. When those horses were treated with Gastrogard for the remaining 30 days, all 16 horses had significantly reduced ulcer scores, researchers note.



 
This study was completely MERIAL funded. They did not release the brands/compounding pharmacy used. It is suspected from ppl who have talked with Dr. Snyder that they didn't even use the buffered omeprazole just like plain powder or paste omeprazole. Sneaky sneaky Merial. ETA: I've used some that I thought was a waste of my money. But Precision pharmacy has always given us results on ulcer horses, so far. I better knock on wood now LOL

Good to know thank you!
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Cowgirl Kat
Reg. Aug 2013
Posted 2015-05-08 3:05 PM
Subject: RE: your favorite Ulcer treatment is......?



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 GastroPLUS!! Never using anything else again. My gelding had such an amazing transformation on it I am so happy and he is happy. Krystal is the best! 
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FlyingJT
Reg. Jan 2014
Posted 2015-05-08 4:22 PM
Subject: RE: your favorite Ulcer treatment is......?



Expert


Posts: 1857
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AngieM1 - 2015-05-08 10:23 AM

RoaniePonie11 - 2015-05-07 7:05 PM

Daily ranitidine users:

How much are you giving??

The drug book at work said 3.3mg/kg every 8 hours or 6.6mg/kg every 12 hours (those are off the top of my head but should be close). That seems like a lot of pills to get a horse to eat twice a day on a daily basis. For a 1200# horse that's roughly 11 tabs twice a day.

Y'all weigh in :)

I feed OTC Ranitidine BJs, Costco, Sams Club etc will have it, even most local Drugs stores. I feed 16 pills 2x a day for my Ulcer horses. It works out to be about 30$ a month that way, some horses (severe cases get 16 pills 3x a day) but it is cheaper to buy it this way I find exactly the same effectiveness as the Ranitidine from the Vet.

The OTC (people version pills) are 150 mg ea.
I also feed 1/3 cup pure aloe juice 2x a day. & 1 - 1.5 lb alfalfa pellets. Wet grain-pellets


My horse also eats better when on Formula 1 Noni.

Ranitidine doesn't shut the acid pump off completely like the omeprazole will do. Ranitidine is more of an AntiAcid. Which is less likely to cause colic. Ive gone over this thousands of time with numerous specialists and I find Ranitidine works more effectively and can be used for very extended periods of time without causing any harm.

Yes and I don't think they can overdose on them..... on accident I gave a gelding 40 pills am & pm for a week once and he had no adverse effects.... But he sure felt good!!!

Edited by FlyingJT 2015-05-08 4:24 PM
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crossarrowk
Reg. Dec 2007
Posted 2015-05-11 10:34 AM
Subject: RE: your favorite Ulcer treatment is......?



Extreme Veteran


Posts: 385
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Location: Texas Big Country
Thank you again everyone very much. This was a great help and I appreciate your expertise and willingness to share.  SK 
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