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EPM...Die Off Symptoms??

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Last activity 2016-06-04 9:49 PM
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epoh
Reg. Dec 2007
Posted 2016-06-01 8:12 PM
Subject: EPM...Die Off Symptoms??



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So long story short, after increasingly worse hypersensitivity/ spooky-ness, sudden drop in weight/topline, finding possums in the barn I ordered Orogin from Pathogenes to treat my mare for epm. I skipped the blood test because my vet agreed that it could be a possibility and if she didnt end up having it then the treatment wont hurt any.
So we are on day 8 of our treatment. Gave her the tablets and about 20 min later she started falling asleep and acting like she didn't know where her limbs were. Any small movement or asking her to walk forward she would become very startled. She had never done this prior to treatment and I know that this startling/limb unawareness is a main symptom of EPM. Planning on calling Pathogenes tomorrow but has anyone had their symptoms get worse during treatment? Heard this was called a die off period?


Edited by epoh 2016-06-01 9:05 PM
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jake16
Reg. Apr 2006
Posted 2016-06-01 8:38 PM
Subject: RE: EPM..Symptoms during treatment??


Go Get Em!


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Location: OH. IO
Kathy ward posted a long journal of her mare.if you do a search and read it does become very heartbreaking at times.Her post has alot of good reading.
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jake16
Reg. Apr 2006
Posted 2016-06-01 8:52 PM
Subject: RE: EPM..Symptoms during treatment??


Go Get Em!


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Location: OH. IO
I bumped up the thread for you:) prayers for your horse.
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soonergirl98
Reg. Oct 2009
Posted 2016-06-01 10:49 PM
Subject: RE: EPM...Die Off Symptoms??



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I treated a gelding with tortazoril? And dmso and he went off feed and water and acted lethargic. I gave him banamine and a tube of In th Zone and stayed the night in his stall the next day he was better. My vet said if they have a lot of protozoa that can happen.
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BARRELHORSE USA
Reg. Sep 2011
Posted 2016-06-01 11:48 PM
Subject: RE: EPM...Die Off Symptoms??




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You know your horse is in real trouble when they lose their legs and go down and can't make that lunge upward while sweeping their back legs under their body ..
and have no balance control while struggling to stand.

The old saying ... if a horse is down 3 days .. his legs are lost and improvement is going to be nothing short of a miracle!!

Once they start laying flat and you do everything you can to keep them resting up right on their breast bone ... they will continue to deteriorate and it is time to make that rainbow bridge decision ..
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quickdraw
Reg. Apr 2009
Posted 2016-06-02 9:56 AM
Subject: RE: EPM...Die Off Symptoms??


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I have treated 3 for EPM and none of them had a negative reaction like that. They simply improved within 7-14 days. However, I have a friend that treated one for EPM, and her horse got a lot worse before he got better. He is now running 1D and no symptoms for close to 2 yrs now. We both treated ours with Marquis (sp?). I think you should definitely consult with your vet asap.
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moeandme2008
Reg. Sep 2008
Posted 2016-06-02 5:10 PM
Subject: RE: EPM...Die Off Symptoms??


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My gelding swelled up on all 4 legs during treatment. They looked like logs. It was due to amount of Protozoa he had. The swelling went away a few days later
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Ashton94
Reg. Feb 2014
Posted 2016-06-02 10:10 PM
Subject: RE: EPM...Die Off Symptoms??



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Posts: 383
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Location: Sweet Home Alabama
I had no idea EPM was so common, but every time I get on here I see a post about it. I pray your mare gets better. I had one pass last August from it. I only got 3 doses of Bayer Marquis in her before she went. I wish more than anything I would have done it sooner.
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blueskies
Reg. Jan 2012
Posted 2016-06-02 10:17 PM
Subject: RE: EPM...Die Off Symptoms??





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Location: Big Blue Skies
Yes! My horse got bad really rapidly. Couldn't walk a straight line. I wasn't sure if she would ever come back. She did get worse at first (with treatment) and I thought it was the EPM but I really think it was the dying off because she was pretty bad. She turned around remarkably after about 2 weeks. She never was 100% but probably 80% which was pretty good considering I was going to put her down. I had to retreat a year later because I saw some symptoms return. I gave mine the high doses of E, and immune builders, and also a natural type wormer. I have sense given Olive Leaf (herb) and Neem powder to help kill off the protozoan. My vet said he thinks the head bob is the first symptom.
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chicks2
Reg. Mar 2007
Posted 2016-06-04 9:49 PM
Subject: RE: EPM...Die Off Symptoms??


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I've treated 3. Most of the time they get worse before they get better.

One didn't get a big dip, he was treated with commercially produced product, Marquiz. Unfortunately he relapsed and didn't respond the the 2nd treatment and was euthanized.

Next one got a compound RX, which is what most docs in N. Texas use, we caught him VERY early, barely any symptoms. He was lethargic and you could tell, just like with your kids, he just didn't feel good. That lasted about a week, he came back full steam no muscle loss. He was in his mid-teens at the time.

Last one had some significant system, 'classic EPM' one vet called it. Used compound medication, not as much reaction as the second one, but still a bit. BTW, we tested him, none of the others, came back negative. Waste of $$$$. He's recovered but did have some muscle loss in his shoulder, but is getting some of it back.

Guess bottom line, keep an eye on them as the protozoa start to die off they feel like crap. If symptoms worsen, call vet, but understand it's not uncommon.

Good luck this whole thing sucks, but it can be treated. I'm in North Texas and this is about as common as sweating in the summer around here. Some folks treat for it routinely.
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