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Veteran
Posts: 161
 
| Does anyone know how long 1/4 of a 227 mg of previcox lasts for pain and inflammation in a horse?? Is it the same amount of time as a 1/2 of a 227 mg?? |
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 BHW Resident Surgeon
Posts: 25351
Location: Bastrop, Texas | I'm not sure that doubling the recommended does give you twice the anti inflammatory effect. I'm not sure it works that way.
Now I assume you are asking if doubling the dose will also prolong the duration of a drug in the bloodstream at levels that are therapeutic, the answer is yes, but a much better approach would be to give that second dose say 12 hours later. You would have therapeutic concentrations of the drug in the bloodstream much longer using that approach. The problem is that the recommended dose in horses is 57 mg daily....not twice daily.
Some people recommend giving a "loading dose" that is twice or even three times the usual recommended daily dose. That supposedly gets to the therapeutic levels much faster. After that, all you need to do is keep up with the daily 57 mg dose. I would NOT recommend doing that without the advice of a good vet. It could be risky in terms of kidney function or GI effects.
Bottom line: Just follow the recommendations. |
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Veteran
Posts: 161
| Thank you! This horse just got a lot of injections and was perscribed a half tablet for 10 days... I was just wondering how long it lasted in a horse.. a normal dose. |
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  Neat Freak
Posts: 11216
Location: Wonderful Wyoming | I have a mare with a needle tearing the cartilage up in her foot. She is only on 1/4 of a tab and it does wonders for her. |
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 Veteran
Posts: 158
| The most I've ever been told was to do a half tab day one, then continue with a quarter tab once a day... a half tab for 10 days would make me nervous about kidney health |
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Miss Southern Sunshine
Posts: 7427
Location: South Central Florida | Not a vet nor did I stay at a Holiday Inn Express last night...but in research I got from my vet, and in private research, Horses do not matabolize Previcox like dogs and more than the 1/4 can damage the liver quickly. Dogs can take 4 times the amound of a Horse. I don't use it for horses, but my Blue Heeler that is 10, broke his neck at age 4, and also has a torn ACL is now on 1/2 a 227 tablet daily. However it makes him feel SO good we are at every other day right now. It is exceptional for arthritice I guess but I would be very careful of too much.
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 You get what you give
Posts: 13030
Location: Texas | I checked the label (for equioxx, which we use the mg/kg dosing from ETA***), you can do 1/2 tab once a day for two days as a loading dose and then drop to the 1/4 tab after. i wouldn't do it for any longer than that.
Edited by casualdust07 2016-11-27 6:28 PM
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The Advice Guru
Posts: 6419
| casualdust07 - 2016-11-27 2:20 PM
I checked the label, you can do 1/2 tab once a day for two days as a loading dose and then drop to the 1/4 tab after. i wouldn't do it for any longer than that.
It is now labelled for horses? |
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You get what you give
Posts: 13030
Location: Texas | cheryl makofka - 2016-11-27 6:01 PM
casualdust07 - 2016-11-27 2:20 PM
I checked the label, you can do 1/2 tab once a day for two days as a loading dose and then drop to the 1/4 tab after. i wouldn't do it for any longer than that.
It is now labelled for horses?
sorry, let me rephrase, thanks for catching. i read the equioxx mg/kg dose which is what we base previcox off. So no previcox is not labeled for horses but their new equioxx pill is.
Edited by casualdust07 2016-11-27 6:30 PM
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The Advice Guru
Posts: 6419
| casualdust07 - 2016-11-27 6:27 PM
cheryl makofka - 2016-11-27 6:01 PM
casualdust07 - 2016-11-27 2:20 PM
I checked the label, you can do 1/2 tab once a day for two days as a loading dose and then drop to the 1/4 tab after. i wouldn't do it for any longer than that.
It is now labelled for horses?
sorry, let me rephrase, thanks for catching. i read the equioxx mg/kg dose which is what we base previcox off. So no previcox is not labeled for horses but their new equioxx pill is.
Thanks I didn't know equinox had a pill developed. Hopefully we get that in Canada soon, I have always hesitated on the orevicoxx due to the flavouring chemicals, I can't see meat flavoured being good for a horse. |
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You get what you give
Posts: 13030
Location: Texas | cheryl makofka - 2016-11-27 6:58 PM
casualdust07 - 2016-11-27 6:27 PM
cheryl makofka - 2016-11-27 6:01 PM
casualdust07 - 2016-11-27 2:20 PM
I checked the label, you can do 1/2 tab once a day for two days as a loading dose and then drop to the 1/4 tab after. i wouldn't do it for any longer than that.
It is now labelled for horses?
sorry, let me rephrase, thanks for catching. i read the equioxx mg/kg dose which is what we base previcox off. So no previcox is not labeled for horses but their new equioxx pill is.
Thanks I didn't know equinox had a pill developed. Hopefully we get that in Canada soon, I have always hesitated on the orevicoxx due to the flavouring chemicals, I can't see meat flavoured being good for a horse.
I personally still just use bute if I have to, because it's stronger. I use all of them sparingly because of GI and renal side effects, but sometimes you just have to use NSAIDs. |
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 Famous for Not Complaining
Posts: 8848
Location: Broxton, Ga | casualdust07 - 2016-11-26 8:02 PM
cheryl makofka - 2016-11-27 6:58 PM
casualdust07 - 2016-11-27 6:27 PM
cheryl makofka - 2016-11-27 6:01 PM
casualdust07 - 2016-11-27 2:20 PM
I checked the label, you can do 1/2 tab once a day for two days as a loading dose and then drop to the 1/4 tab after. i wouldn't do it for any longer than that.
It is now labelled for horses?
sorry, let me rephrase, thanks for catching. i read the equioxx mg/kg dose which is what we base previcox off. So no previcox is not labeled for horses but their new equioxx pill is.
Thanks I didn't know equinox had a pill developed. Hopefully we get that in Canada soon, I have always hesitated on the orevicoxx due to the flavouring chemicals, I can't see meat flavoured being good for a horse.
I personally still just use bute if I have to, because it's stronger. I use all of them sparingly because of GI and renal side effects, but sometimes you just have to use NSAIDs.
I prefer bute as well haven't had much success with Previcox....."dog tab"......
Edited by CJE 2016-11-28 11:56 AM
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