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  Damn Yankee
Posts: 12390
   
Location: Somewhere between raising hell and Amazing Grace | We can keep this anonymous but I'm curious....who uses it an why? |
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 The Worst Seller Ever
Posts: 4138
Location: Oklahoma | I have used it on a couple different horses for breathing issues when I was running. I used strictly for that issue.
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Hungarian Midget Woman
Location: Midwest | I don't use it now, but if I had a horse with airway issues and a vet prescribed it I would use it, barring it was legal in the rule book for that event. |
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Damn Yankee
Posts: 12390
Location: Somewhere between raising hell and Amazing Grace | I used it on my best horse years and years ago with success. I have tried it on two horses since then with very negative reactions. They get severely agitated, heart racing, and break out sweating horribly. With my current horse, a bleeder with a restricted airway, I just feel like I am doing more for him by using other products then ventipulmon, but i am just curious. I remember years ago it was the hot thing on the market. But now I wonder just how hot it still is and if ppl still use it. I came across an old friend the other day that is going to use is strictly as a performance enhancer because she can. |
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The Advice Guru
Posts: 6419
| We're you giving iv or po?
Just read in my vet drug book it says adverse effects at high doses can cause tachycardia and tremors.
I had one horse who for 2 years would get chronic lung infections, he was always on it, I had the iv on hand in case his breathing got too bad, never had to use it thank goodness.
If you are having good results with others great, I don't change what isn't broken
Edited by cheryl makofka 2014-05-29 1:26 PM
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Damn Yankee
Posts: 12390
Location: Somewhere between raising hell and Amazing Grace | po, and I think the heart rate increase was a result of nerves and agitation. Not necessarily from the ventipulmon. I don't have any plans of using it on my current horses, I'm just asking out of curiosity and boredom, and because it's a horse topic :) |
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 Coyote Country Queen
Posts: 5666
| I have used it with my horse that has a breathing issue. It was prescribed by a vet. I have since switched to a different product, but still have some in the medicine cabinet in case I need to use it.
Just curious, what products are you using for your bleeder with restricted airway? I've been struggling with my mare, and it gets much worse in the spring, so I'm assuming hers is allergy/dust related. She has been scoped, but don't have access after a run, so I don't know for sure if she's bleeding or not, but vet suggested I run her on Lasix so I do. I've got her on Tri-Hist and use a product to open her airways prior to riding (Super Wind). A couple of days ago my vet suggested a shot, can't remember for sure the name, something like betamethasone, and that seemed to help quite a bit. She had been off of the Tri-Hist for several months, but I had to put her back on it recently to help with her breathing. |
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 Expert
Posts: 5293
| My good horse has been on it for over a year. He has really bad dust allergies. I use it the day before a run, day of, and smaller dose day after. |
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 Rebel Without a Cause
Posts: 2758
Location: Adopt a homeless pet - www.petfinder.com! | Used it when I lived in very dry conditions out west and horse developed a dry cough due to dust. Used it when I ran and for daily riding. Was eventually able to discontinue it. |
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 Voice of Reason
Location: NOT at Wal Mart | Clenbuterol is a bronchodilator, when usen in high doses it will cause sweating, tachycardia and restlessness. Lower the dose and go from there, also it will not enhance performance if the horse has normal lung function. The drug works and I have used it with great success in the past.
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Expert
Posts: 4766
Location: Bandera, TX | I really like using Ventipulmin via inhalation. It cuts down on the "Jitters" the beta 2 effects are affecting the very target tissue, the lungs and the Beta 1 effects on the heart are much milder.
If your horses is having seasonal allergies test for the cause then treat.
I sure hate giving Ventipulmin to rank horses it just makes your warm up miserable, not to mention how the horse must feel with their heart rate up. Laid back horses that need it I have no problems using it PO.
For the horse that ran better on the beclomethasone, have your tried Fluticasone? It's had great results for long term use and less side effects. Some believe that horses are "cured" by its use.
I'm going to try to find a good write up on these meds for you. |
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 You get what you give
Posts: 13030
Location: Texas | Ventipulmin is a beta-2 agonist
Horses, unlike most other animals, are adrenergic sweaters. Norepinephrine is the neurotransmitter for horses to sweat, whereas acetylcholine is the neurotransmitter for other animals. Those animals are muscarinic cholinergic sweaters.
Long story short- give a beta 2 agonist like ventipulmin- you get beta 2 effects- bronchodilation, and sweating.
I'm reading up on why the tachycardia happens sometimes… I will return! |
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Expert
Posts: 4766
Location: Bandera, TX | I hope this link will work for you... http://www.thehorse.com/articles/15922/inhalation-therapy-for-equine-airway-disease
OP, thank you, love discussing the issues that affect our horses and have so much impact on their longevity. |
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You get what you give
Posts: 13030
Location: Texas | As to the when/why we use it…
I've kept it on hand in the past because our summers get very hot and every once in a while we will have a horse get heavey in the summer. IDK if its the fact they quit sweating that they started the heave like breathing, or if they were just heavey from allergies and miserable. I would give it to them and they would start sweating and their breathing would calm back down.
We have an old mare who we run on ventipulmin just the day of the race and on half the recommended dose. We have cicatrix in our area, and there's really not much to do about it other than not turn out horses, or try the pythium vaccine which I am not sold on. her airways are a bit scarred up so she runs on it.
I wonder if there's not a cross reactivity sometimes with beta-1 receptors that can sometimes cause tachycardia? my guess.. don't know yet. |
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Expert
Posts: 4766
Location: Bandera, TX | casualdust07 - 2014-05-29 2:11 PM Ventipulmin is a beta-2 agonist Horses, unlike most other animals, are adrenergic sweaters. Norepinephrine is the neurotransmitter for horses to sweat, whereas acetylcholine is the neurotransmitter for other animals. Those animals are muscarinic cholinergic sweaters. Long story short- give a beta 2 agonist like ventipulmin- you get beta 2 effects- bronchodilation, and sweating. I'm reading up on why the tachycardia happens sometimes… I will return!
It has some beta 1 activity. |
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You get what you give
Posts: 13030
Location: Texas | uno-dos-tres! - 2014-05-29 2:19 PM
casualdust07 - 2014-05-29 2:11 PM Ventipulmin is a beta-2 agonist Horses, unlike most other animals, are adrenergic sweaters. Norepinephrine is the neurotransmitter for horses to sweat, whereas acetylcholine is the neurotransmitter for other animals. Those animals are muscarinic cholinergic sweaters. Long story short- give a beta 2 agonist like ventipulmin- you get beta 2 effects- bronchodilation, and sweating. I'm reading up on why the tachycardia happens sometimes… I will return!
It has some beta 1 activity. Â
Yep that's the reason. My friend confirmed..LOL we are bored this summer! the beta 1 activity causes vasodilation which will cause a drop in blood pressure.. heart rate increases to compensate |
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 Famous for Not Complaining
Posts: 8848
Location: Broxton, Ga | justcruzin - 2014-05-28 3:07 PM Clenbuterol is a bronchodilator, when usen in high doses it will cause sweating, tachycardia and restlessness. Lower the dose and go from there, also it will not enhance performance if the horse has normal lung function. The drug works and I have used it with great success in the past.
Some will disagree with you............or so they believe........... |
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Expert
Posts: 4766
Location: Bandera, TX | Iv'e learned lots out of boredom! |
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You get what you give
Posts: 13030
Location: Texas | yep we covered the basics of alpha and beta agonists/antagonists in physiology last year but I'm sure my mind will be blown when we take pharmacology next year..
My prof told me that a normal horse will be dilated as much as they possibly can, therefore giving them a bronchodilator won't dilate them anymore…That being said, I do know people have described anabolic like effects when giving ventipulmin long term. so maybe theres something more that goes on |
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 BHW Resident Surgeon
Posts: 25352
Location: Bastrop, Texas | justcruzin - 2014-05-29 2:07 PM
 Clenbuterol is a bronchodilator, when usen in high doses it will cause sweating, tachycardia and restlessness. Lower the dose and  go from there, also it will not enhance performance if  the horse has normal lung function. The drug works and I have used it with great success in the past.
Â
I think this is correct. |
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