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Adequan... Loading dose or Not?

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Last activity 2015-09-10 11:01 AM
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Poohb10454
Reg. Apr 2013
Posted 2015-09-05 5:36 PM
Subject: Adequan... Loading dose or Not?



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I am starting my 12 year old gelding on monthly Adequan IM injections for prevention. He currently has no joint issues, has been on oral joint supplements for prevention in the past. Will I need to start with the loading dose? I'd love to hear personal experiences. The vet said with no joint problems I could just start with monthly injections. However, I have also read online that it is just a waste of money without the loading dose.

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SG.
Reg. Sep 2003
Posted 2015-09-05 5:55 PM
Subject: RE: Adequan... Loading dose or Not?


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 Absolutely you do a loading dose.  Because if you don't you might as well don't do it.  You have to get the blood levels up and then maintain them
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FLITASTIC
Reg. Jun 2012
Posted 2015-09-05 7:17 PM
Subject: RE: Adequan... Loading dose or Not?



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It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
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kaleydanielle
Reg. Jul 2006
Posted 2015-09-05 7:20 PM
Subject: RE: Adequan... Loading dose or Not?


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I do a loading dose once or twice a year and no monthly shots.
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SG.
Reg. Sep 2003
Posted 2015-09-05 8:06 PM
Subject: RE: Adequan... Loading dose or Not?


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FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.

 ?  Do you have a link on this?  I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days.  I would love to learn more
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FLITASTIC
Reg. Jun 2012
Posted 2015-09-05 11:47 PM
Subject: RE: Adequan... Loading dose or Not?



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SG. - 2015-09-05 6:06 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.

 ?  Do you have a link on this?  I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days.  I would love to learn more

I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.
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Poohb10454
Reg. Apr 2013
Posted 2015-09-06 8:40 AM
Subject: RE: Adequan... Loading dose or Not?



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Thank you for the replies. I did the first shot yesterday and will go ahead and do the full loading dose, and then go from there to decide about monthly or doing the 7 shot series once or twice a year.
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CocoChex
Reg. Mar 2013
Posted 2015-09-06 9:46 AM
Subject: RE: Adequan... Loading dose or Not?



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FLITASTIC - 2015-09-05 11:47 PM

SG. - 2015-09-05 6:06 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.

 ?  Do you have a link on this?  I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days.  I would love to learn more

I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.

My vet also told me this as well. I have switched from loading dose and monthly to loading dose 2x a year and an seeing better results.
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cowpatty
Reg. Dec 2005
Posted 2015-09-06 12:32 PM
Subject: RE: Adequan... Loading dose or Not?


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loading dose every 4days or 7?,
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geronabean
Reg. Sep 2003
Posted 2015-09-06 12:35 PM
Subject: RE: Adequan... Loading dose or Not?


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FLITASTIC - 2015-09-05 8:17 PM

It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.

This is what I have been hearing.
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astreakinchic
Reg. Sep 2011
Posted 2015-09-06 1:18 PM
Subject: RE: Adequan... Loading dose or Not?


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FLITASTIC - 2015-09-06 12:47 AM

SG. - 2015-09-05 6:06 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.

 ?  Do you have a link on this?  I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days.  I would love to learn more

I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.

He is correct call a rep of the company
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SG.
Reg. Sep 2003
Posted 2015-09-06 3:19 PM
Subject: RE: Adequan... Loading dose or Not?


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FLITASTIC - 2015-09-05 11:47 PM
SG. - 2015-09-05 6:06 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
 ?  Do you have a link on this?  I have used it for over 12 years this way with great results and everything I have read on the research has proven the once every 21 days.  I would love to learn more
I was actually told this by Several of the vets I use. They said they got the info and research from the manufacturer. It's approved and labeled for 7 shot series. Not monthly.

 Thank you for this info
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r_beau
Reg. Apr 2010
Posted 2015-09-06 6:17 PM
Subject: RE: Adequan... Loading dose or Not?



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FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 

So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.


To the OP: YES you need to do a loading dose, regardless.

 

Edited by r_beau 2015-09-06 6:24 PM
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FLITASTIC
Reg. Jun 2012
Posted 2015-09-06 9:42 PM
Subject: RE: Adequan... Loading dose or Not?



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r_beau - 2015-09-06 4:17 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 

So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.


To the OP: YES you need to do a loading dose, regardless.

 

Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.
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casualdust07
Reg. Mar 2005
Posted 2015-09-06 10:17 PM
Subject: RE: Adequan... Loading dose or Not?



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FLITASTIC - 2015-09-06 9:42 PM

r_beau - 2015-09-06 4:17 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 

So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.


To the OP: YES you need to do a loading dose, regardless.

 

Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.

whats Curost?
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Chandler's Mom
Reg. Jan 2015
Posted 2015-09-06 10:25 PM
Subject: RE: Adequan... Loading dose or Not?



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casualdust07 - 2015-09-06 10:17 PM

FLITASTIC - 2015-09-06 9:42 PM

r_beau - 2015-09-06 4:17 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 

So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.


To the OP: YES you need to do a loading dose, regardless.

 

Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.

whats Curost?

Herbie, come forth!!!
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barrelracr131
Reg. Aug 2011
Posted 2015-09-07 6:40 AM
Subject: RE: Adequan... Loading dose or Not?


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casualdust07 - 2015-09-06 10:17 PM

FLITASTIC - 2015-09-06 9:42 PM

r_beau - 2015-09-06 4:17 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 

So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.


To the OP: YES you need to do a loading dose, regardless.

 

Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.

whats Curost?

An herbal supplement
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casualdust07
Reg. Mar 2005
Posted 2015-09-07 8:53 AM
Subject: RE: Adequan... Loading dose or Not?



You get what you give


Posts: 13030
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barrelracr131 - 2015-09-07 6:40 AM

casualdust07 - 2015-09-06 10:17 PM

FLITASTIC - 2015-09-06 9:42 PM

r_beau - 2015-09-06 4:17 PM

FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 

So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.


To the OP: YES you need to do a loading dose, regardless.

 

Then we have Dr Schell at curost who doesn't really think we need ANy of the shots in the first place if you manage the inflammation. My horse with hock arthritis, coffin joint arthritis and broken navicular bone May 1 has been on curost total support for 45 days and made a rodeo run today and was 100 percent sound when it was over. Normally he runs on previcox and pentosan etc. took him off just to see.

whats Curost?

An herbal supplement

oh ok thanks
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SG.
Reg. Sep 2003
Posted 2015-09-07 10:28 AM
Subject: RE: Adequan... Loading dose or Not?


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I went to the manufacturer as you suggested and yes the directions have changed since I read it last. 
Wow
 
Studies show that administering Adequan®i.m. as recommended—500 mg intramuscularly once every four days for 28 days or seven treatments—better than results with four-injection series.*
http://www.adequan.com/recommended_dosage.aspx

http://www.adequan.com/clinical_studies.aspx

I have been sorta doing this with one of my older mares, just because it seems to work.  I had been doing a box every 4 days  then she would get really good and about 3 months later I would need to do it again.  So  I will continue.  Thanks for the heads up that this has changed

Edited by SG. 2015-09-07 10:30 AM
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r_beau
Reg. Apr 2010
Posted 2015-09-08 5:29 PM
Subject: RE: Adequan... Loading dose or Not?



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r_beau - 2015-09-06 6:17 PM
FLITASTIC - 2015-09-05 7:17 PM It's actually more effective to do the loading dose 2x a year and not monthly. Monthly has not shown any benefit.
My vet disagrees and says it actually hasn't been PROVEN to do two loading doses a year. 



So I am continuing on with once a month, as recommended by her. She's a younger vet and very up-to-date, totally trust her. Come to think of it, I've been meaning to email the other vet that I have used (one of the best in the region) and see what his reponse is. So far, he's always agreed with my vet I use here.





To the OP: YES you need to do a loading dose, regardless.


 

Got a response from my other vet. 

He said to do the loading dose in the spring, and then every month thereafter.

 
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