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Never Named
Posts: 1837
   
Location: Southern Alabama | Anything and everything.
?The good, the bad and the ugly. I have never had much experience with it. |
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  Neat Freak
Posts: 11216
Location: Wonderful Wyoming | my understanding is if they have it, they have a pretty bad life. Any cut or bump on the skin and tear it.
http://equusmagazine.com/article/case-report-hereditary-equine-regional-dermal-asthenia-herda-8443
https://www.vgl.ucdavis.edu/services/herda.php
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 Horsey Gene Carrier
Posts: 1888
Location: LaBelle, Florida | Herda: nasty nasty problem. Basically the skin seperates from the body. So any dent, ding, or bruise will turn real ugly, real quick.
Usually rearing its ugly head when it comes time to saddle break. Bruising from ill fitting saddle, girth, etc turns into epic wounds that won't or can't heal.
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 Texas Taco
Posts: 7499
Location: Bandera, TX | It's genetic. No cure.
Why do you ask? |
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 Extreme Veteran
Posts: 415
| It's a death sentence |
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Elite Veteran
Posts: 953
| So why do we keep letting stallions that are postive or carry the gene keep breeding???? This is what I don't understand..... |
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 Regular
Posts: 73
Location: Central Texas | Your horse has to carry both genes to be symptomatic (homozygous). If they are heterozygous HERDA, they are not symptomatic and you can still breed them so long as stallion/broodmare is double negative. |
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Neat Freak
Posts: 11216
Location: Wonderful Wyoming | cowgirl156 - 2016-12-27 6:56 PM So why do we keep letting stallions that are postive or carry the gene keep breeding???? This is what I don't understand.....
because money is more important than bettering the breed. |
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 Take a Picture
Posts: 12842
| The chance of a horse having HERDA is very slim. Supposedly linked to Poco Bueno. I had a grandson of Poco Bueno. He lived to be 32 years old. I have never seen or heard of a horse with HERDA in over 60 years of registered horses. |
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Extreme Veteran
Posts: 415
| streakysox - 2016-12-27 9:51 PM The chance of a horse having HERDA is very slim. Supposedly linked to Poco Bueno. I had a grandson of Poco Bueno. He lived to be 32 years old. I have never seen or heard of a horse with HERDA in over 60 years of registered horses.
A Smooth Guy is HERDA and GBED positive... |
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Horsey Gene Carrier
Posts: 1888
Location: LaBelle, Florida | If you breed responsibly (ie test mare and stallionand bred accordingly), there is not issue.
If you took every animal out of the breeding population that is a genetic carrier for a problem, there would be a VERY small pool of breeding animals left.
The Arabian community has this figured out. They test for SCID, some of the best breeding animals are carriers.
If being a carrier causes no health issue, why not still use that animal (if said animal has everything else going for it)? |
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Never Named
Posts: 1837
Location: Southern Alabama | I ask because..... my grulla mare is heterozygous for HERDA. She carries the gene, but, is not affected by it. I know nothing about it so, I want to strengthen my knowledge base. |
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 Star Padded Honey
Posts: 8890
Location: NW MT | kasaj2000 - 2016-12-28 4:11 AM If you breed responsibly (ie test mare and stallionand bred accordingly), there is not issue.
If you took every animal out of the breeding population that is a genetic carrier for a problem, there would be a VERY small pool of breeding animals left.
The Arabian community has this figured out. They test for SCID, some of the best breeding animals are carriers.
If being a carrier causes no health issue, why not still use that animal (if said animal has everything else going for it)?
BUT - way too many use the word "Carrier" if they horse has one gene for PSSM for example (or HYPP), PSSM N/P1. They are NOT carriers in these diseases - they HAVE it. It only takes one to have it. Many people do not understand this and it's all about education. WAY too many breeders out there still breeding these diseases ahead and some that flat out LIE to their customers.  |
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Never Named
Posts: 1837
Location: Southern Alabama | Rockyroad - 2016-12-28 8:20 AM kasaj2000 - 2016-12-28 4:11 AM If you breed responsibly (ie test mare and stallionand bred accordingly), there is not issue.
If you took every animal out of the breeding population that is a genetic carrier for a problem, there would be a VERY small pool of breeding animals left.
The Arabian community has this figured out. They test for SCID, some of the best breeding animals are carriers.
If being a carrier causes no health issue, why not still use that animal (if said animal has everything else going for it)? BUT - way too many use the word "Carrier" if they horse has one gene for PSSM for example (or HYPP), PSSM N/P1. They are NOT carriers in these diseases - they HAVE it. It only takes one to have it. Many people do not understand this and it's all about education. WAY too many breeders out there still breeding these diseases ahead and some that flat out LIE to their customers.
My grulla mare is a carrier for HERDA, not active, however. She has had genetic testing done and, they say that she carries the gene, but, is not affected by the gene. |
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 Extreme Veteran
Posts: 356
| In the case of HERDA, yes, they have to be homozygous to actually have the disease. If they're heterozygous they're a true carrier. If you decide to breed her, just be sure to choose a stallion that is not a carrier.
HERDA is a recessive genetic disorder, which is why heterozygous horses are considered carriers. A HERDA heterozygous horse will not experience symptoms of the disease, while a HERDA homozygous horse will.
HYPP is a dominant gene, so it's not possible for a horse to be a "carrier". An HYPP heterozygous horse may not experience symptoms as extreme as an HYPP homozygous horse, but they can still be affected by the disease.
PSSM is also a dominant gene, so same goes as for HYPP. |
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Elite Veteran
Posts: 953
| cheeka77 - 2016-12-28 1:31 AM
streakysox - 2016-12-27 9:51 PM The chance of a horse having HERDA is very slim. Supposedly linked to Poco Bueno. I had a grandson of Poco Bueno. He lived to be 32 years old. I have never seen or heard of a horse with HERDA in over 60 years of registered horses.
A Smooth Guy is HERDA and GBED positive...
Yup and this is why I won't breed to him. |
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Take a Picture
Posts: 12842
| cheeka77 - 2016-12-28 1:31 AM
streakysox - 2016-12-27 9:51 PM The chance of a horse having HERDA is very slim. Supposedly linked to Poco Bueno. I had a grandson of Poco Bueno. He lived to be 32 years old. I have never seen or heard of a horse with HERDA in over 60 years of registered horses.
A Smooth Guy is HERDA and GBED positive...
I said I had never heard of a horse with HERDA. Did not say anything about being a carrier. Lets read more carefully. In the future I will try to word things more carefully so it is easier to understand.
Edited by streakysox 2016-12-28 1:18 PM
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Horsey Gene Carrier
Posts: 1888
Location: LaBelle, Florida | Rockyroad - 2016-12-28 9:20 AM kasaj2000 - 2016-12-28 4:11 AM If you breed responsibly (ie test mare and stallionand bred accordingly), there is not issue.
If you took every animal out of the breeding population that is a genetic carrier for a problem, there would be a VERY small pool of breeding animals left.
The Arabian community has this figured out. They test for SCID, some of the best breeding animals are carriers.
If being a carrier causes no health issue, why not still use that animal (if said animal has everything else going for it)? BUT - way too many use the word "Carrier" if they horse has one gene for PSSM for example (or HYPP), PSSM N/P1. They are NOT carriers in these diseases - they HAVE it. It only takes one to have it. Many people do not understand this and it's all about education. WAY too many breeders out there still breeding these diseases ahead and some that flat out LIE to their customers.
I agree, too many will lie. Which is why it pays to do your homework and ask questions, which is what I gather the op is trying to do. |
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 My Heart Be Happy
Posts: 9159
Location: Arkansas | k.maddocks24 - 2016-12-28 8:43 AM
In the case of HERDA, yes, they have to be homozygous to actually have the disease. If they're heterozygous they're a true carrier. If you decide to breed her, just be sure to choose a stallion that is not a carrier.
HERDA is a recessive genetic disorder, which is why heterozygous horses are considered carriers. A HERDA heterozygous horse will not experience symptoms of the disease, while a HERDA homozygous horse will.
HYPP is a dominant gene, so it's not possible for a horse to be a "carrier". An HYPP heterozygous horse may not experience symptoms as extreme as an HYPP homozygous horse, but they can still be affected by the disease.
PSSM is also a dominant gene, so same goes as for HYPP.
I believe MS State and one other university do extensive research on HERDA. There were some articles in Quarter Horse News several years ago; it was very interesting (sad) reading. People that owned some affected horses obviously never broke them to saddle and just hoped and prayed they never had an accident where the skin was cut or split open. They just let them live out their lives in the pasture. Others of course euthanized them upon diagnosis. Some of the pictures were horrifying. . . . |
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Extreme Veteran
Posts: 415
| streakysox - 2016-12-28 1:15 PM cheeka77 - 2016-12-28 1:31 AM streakysox - 2016-12-27 9:51 PM The chance of a horse having HERDA is very slim. Supposedly linked to Poco Bueno. I had a grandson of Poco Bueno. He lived to be 32 years old. I have never seen or heard of a horse with HERDA in over 60 years of registered horses. A Smooth Guy is HERDA and GBED positive... I said I had never heard of a horse with HERDA. Did not say anything about being a carrier. Lets read more carefully. In the future I will try to word things more carefully so it is easier to understand.
Yes, maybe just try to word things more carefully if you're going to get crabby about a sentence response (and honest reply). Sorry! |
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