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Elite Veteran
Posts: 863
  
| I was recently told by one of our vets to use Legend IV for joint therapy versus adequan every week when hauling..that legend is better. I thought a few years ago I was told Legend doesn't last long in the body? Then I hear hunter/jumpers that use BOTH. My good horse isn't horrible, but will need hocks injected before the show season starts..vet said Legend could prolong that injection? Just would love to hear testimony on all 3 of these. Thank you |
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Elite Veteran
Posts: 618
| Legend and Adequan are 2 very different meds. Pentosan is similar to Adequan.
https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.iro...
Edited by iloveequine40 2018-03-06 7:32 PM
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 Expert
Posts: 5290
| Legend only lasts 36-48 hours at the most. It reaches maximum effect at 8-12 hours. Only goes down hill from there. I give it the night before a morning race or the morning of a night race. I also use adequan. Two full 7 shot series twice a year at 6 month intervals. Lubrisyn daily.
Edited by FLITASTIC 2018-03-06 7:46 PM
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Elite Veteran
Posts: 863
| FLITASTIC - 2018-03-06 7:44 PM
Legend only lasts 36-48 hours at the most. It reaches maximum effect at 8-12 hours. Only goes down hill from there. I give it the night before a morning race or the morning of a night race. I also use adequan. Two full 7 shot series twice a year at 6 month intervals. Lubrisyn daily.
This is what I've heard in the past that Legend only lasts short time period...then this one vet says one shot of Legend is good for at least 2 months..it gets confusing. Most people I know use Adequan or Pentosan around me. Thanks. |
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Expert
Posts: 5290
| Just read a recent study that legend is not even detectable after THREE hours from the time it was given! Lol adequan is slow and steady and helps a horse LONG TERM |
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Elite Veteran
Posts: 863
| FLITASTIC - 2018-03-06 10:41 PM
Just read a recent study that legend is not even detectable after THREE hours from the time it was given! Lol adequan is slow and steady and helps a horse LONG TERM
Thanks! Now to find the best place to order either Adequan or Pentosan at..I hear Pentosan is quite a bit more reasonable. I know my vet doesn't sell it though :( |
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 The One
Posts: 7997
Location: South Georgia | I have used Pentosan after hock injections to maintain. I paid $270 for a bottle and it lasted me about 4 months with a loading injection and then bi-weekly injections. |
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Elite Veteran
Posts: 863
| horsegirl - 2018-03-07 6:35 AM
I have used Pentosan after hock injections to maintain. I paid $270 for a bottle and it lasted me about 4 months with a loading injection and then bi-weekly injections.
Where do you order yours from? I just read stories to stay clear from HorsePreRace.com |
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The One
Posts: 7997
Location: South Georgia | Wild1 - 2018-03-07 7:44 AM horsegirl - 2018-03-07 6:35 AM I have used Pentosan after hock injections to maintain. I paid $270 for a bottle and it lasted me about 4 months with a loading injection and then bi-weekly injections. Where do you order yours from? I just read stories to stay clear from HorsePreRace.com
My vet. He doesn't upcharge. |
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Elite Veteran
Posts: 897
| I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month. |
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Expert
Posts: 5290
| emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot. |
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Elite Veteran
Posts: 897
| FLITASTIC - 2018-03-07 7:41 AM
emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot.
Thanks! I will definitely talk to my vet about that! We did do the 7 shots 4 days apart when we started, then she said to do a shot once a month on the 28th.. |
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Expert
Posts: 5290
| emricmacy - 2018-03-07 6:28 AM
FLITASTIC - 2018-03-07 7:41 AM
emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot.
Thanks! I will definitely talk to my vet about that! We did do the 7 shots 4 days apart when we started, then she said to do a shot once a month on the 28th..
Yep that was the " Original" recommendation. THen it was researched and the medication you give one day takes about 2 weeks to really get where it needs to go ( Yes there is some immediate inflammation reduction) so thats why you give every 4 days to begin with. SO the tissues are constantly exposed over a 28 day period. one single shot every 28 days does nothing. |
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Elite Veteran
Posts: 897
| FLITASTIC - 2018-03-07 9:26 AM
emricmacy - 2018-03-07 6:28 AM
FLITASTIC - 2018-03-07 7:41 AM
emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot.
Thanks! I will definitely talk to my vet about that! We did do the 7 shots 4 days apart when we started, then she said to do a shot once a month on the 28th..
Yep that was the " Original" recommendation. THen it was researched and the medication you give one day takes about 2 weeks to really get where it needs to go ( Yes there is some immediate inflammation reduction ) so thats why you give every 4 days to begin with. SO the tissues are constantly exposed over a 28 day period. one single shot every 28 days does nothing.
So what about all the time in between those two series twice a year? |
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Expert
Posts: 5290
| emricmacy - 2018-03-07 10:27 AM
FLITASTIC - 2018-03-07 9:26 AM
emricmacy - 2018-03-07 6:28 AM
FLITASTIC - 2018-03-07 7:41 AM
emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot.
Thanks! I will definitely talk to my vet about that! We did do the 7 shots 4 days apart when we started, then she said to do a shot once a month on the 28th..
Yep that was the " Original" recommendation. THen it was researched and the medication you give one day takes about 2 weeks to really get where it needs to go ( Yes there is some immediate inflammation reduction ) so thats why you give every 4 days to begin with. SO the tissues are constantly exposed over a 28 day period. one single shot every 28 days does nothing.
So what about all the time in between those two series twice a year?
Research by Luitpold shows that after a 7 dose series the effects of adequan remain inside the joint capsule for up to a year. For some horses that are not used hard, they may only need a once a year series. Twice a year keeps a constant high level of the drug in the capsule. I son't know all the chemical compounds etc to explain that side of it. My vet said they added something to the adequan like a " Marker" that could tell how long it took to get where it needed to go, and how long it lasted. Thats about the best way I can explain it.. The once a month was not effective at keeping levels high in the joint. You need to do a series.
Edited by FLITASTIC 2018-03-07 12:36 PM
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Elite Veteran
Posts: 863
| Would Pentosan be in the same dosage range like adequan then? I know I need to ask my vet but I thought I'd quick as on here too |
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Elite Veteran
Posts: 897
| FLITASTIC - 2018-03-07 12:35 PM
emricmacy - 2018-03-07 10:27 AM
FLITASTIC - 2018-03-07 9:26 AM
emricmacy - 2018-03-07 6:28 AM
FLITASTIC - 2018-03-07 7:41 AM
emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot.
Thanks! I will definitely talk to my vet about that! We did do the 7 shots 4 days apart when we started, then she said to do a shot once a month on the 28th..
Yep that was the " Original" recommendation. THen it was researched and the medication you give one day takes about 2 weeks to really get where it needs to go ( Yes there is some immediate inflammation reduction ) so thats why you give every 4 days to begin with. SO the tissues are constantly exposed over a 28 day period. one single shot every 28 days does nothing.
So what about all the time in between those two series twice a year?
Research by Luitpold shows that after a 7 dose series the effects of adequan remain inside the joint capsule for up to a year. For some horses that are not used hard, they may only need a once a year series. Twice a year keeps a constant high level of the drug in the capsule. I son't know all the chemical compounds etc to explain that side of it. My vet said they added something to the adequan like a " Marker" that could tell how long it took to get where it needed to go, and how long it lasted. Thats about the best way I can explain it.. The once a month was not effective at keeping levels high in the joint. You need to do a series.
Wow! Thank you for all the advice! My vet asked me last visit if I see him declining around the time of the shot every month (the 28th)..I said I didn't think so. She said some of her clients say their horses are more sore when they are due for a shot on the 28th..
It sounds like I should probably switch to the twice a year..but how do I go about doing that since I give once a month? When do I start the loading dose again?
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The One
Posts: 7997
Location: South Georgia | Wild1 - 2018-03-07 2:07 PM Would Pentosan be in the same dosage range like adequan then? I know I need to ask my vet but I thought I'd quick as on here too
I'm wondering as well! |
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Expert
Posts: 5290
| Wild1 - 2018-03-07 11:07 AM
Would Pentosan be in the same dosage range like adequan then? I know I need to ask my vet but I thought I'd quick as on here too
I want to say pentosan is one shot a week for 4 weeks then monthly. Just make sure with pentosan that you don't give it to a bleeder ever and never within 4 days of a run in case they bleed. It is an anticoagulant. I did use it on a couple horses that were not competitive horses and just needed joint support. |
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Expert
Posts: 5290
| emricmacy - 2018-03-07 11:08 AM
FLITASTIC - 2018-03-07 12:35 PM
emricmacy - 2018-03-07 10:27 AM
FLITASTIC - 2018-03-07 9:26 AM
emricmacy - 2018-03-07 6:28 AM
FLITASTIC - 2018-03-07 7:41 AM
emricmacy - 2018-03-07 5:35 AM
I pay $385 for a bottle on Adequan from my vet. It's the best price I have found so far. I give it once a month.
The makers of adequan did a study and found that monthly adequan does absolutely nothing. My vet agrees. The way it works, it needs repeated exposure to joint tissue over a months time to be effective. That is why you need the 7 shots 4 days apart. It is far more effective to give 2 full 7 shot series twice a year rather then monthly 1 shot.
Thanks! I will definitely talk to my vet about that! We did do the 7 shots 4 days apart when we started, then she said to do a shot once a month on the 28th..
Yep that was the " Original" recommendation. THen it was researched and the medication you give one day takes about 2 weeks to really get where it needs to go ( Yes there is some immediate inflammation reduction ) so thats why you give every 4 days to begin with. SO the tissues are constantly exposed over a 28 day period. one single shot every 28 days does nothing.
So what about all the time in between those two series twice a year?
Research by Luitpold shows that after a 7 dose series the effects of adequan remain inside the joint capsule for up to a year. For some horses that are not used hard, they may only need a once a year series. Twice a year keeps a constant high level of the drug in the capsule. I son't know all the chemical compounds etc to explain that side of it. My vet said they added something to the adequan like a " Marker" that could tell how long it took to get where it needed to go, and how long it lasted. Thats about the best way I can explain it.. The once a month was not effective at keeping levels high in the joint. You need to do a series.
Wow! Thank you for all the advice! My vet asked me last visit if I see him declining around the time of the shot every month (the 28th )..I said I didn't think so. She said some of her clients say their horses are more sore when they are due for a shot on the 28th..
It sounds like I should probably switch to the twice a year..but how do I go about doing that since I give once a month? When do I start the loading dose again?
When I switched from monthly I just used my regular monthly dose as the first of my 7 shot series and gave 6 additional shots 4 days apart. |
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