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EPM diagnosis....now what?

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Longneck
Reg. Mar 2004
Posted 2014-12-30 1:35 PM
Subject: RE: EPM diagnosis....now what?


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wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM
wyoming barrel racer - 2014-12-30 12:26 PM
FlyingJT - 2014-12-30 11:13 AM
Longneck - 2014-12-30 9:35 AM
FlyingJT - 2014-12-30 9:29 AM Start treating right away! don't wait for the vitamin E to come in, it's not going to effect the drugs either way. Keep him on the vitamin E for as long as you can. You might also find another supplement to help with inflammation along with the vitamin E. I've heard people talk about Duralactin, but I haven't done any research on it so i'm not sure if it works or not.
Thanks!  I have an inflammation blend in his THE blend, I think it helped with his suspensories so hopefully it'll keep helping with this...... Do you think I should give him some bute for a couple of days until the Orogin gets in? 
It most certainly wouldn't hurt. 2 grams a day. I'm all for anything that will give the horse the upper hand on the EPM. And remember to give him time after treatment to allow his immune system to rebound. Same goes for when you bring him back to full work. Slow!
How long do you give the Orogin/Oroquin-10 and what is a schedule to bring them back? Mine has literally been hanging out in the corral since August. I planned to give his ligament off until at least Spring-April/May. Then if he vet checks out I was going to send him off for another 30 days riding. 
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results

SAG 1, 5, 6 are 2

CRP/Lyme Titer 11

What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.



My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...

I am in the same boat as you... when I read that EPM causes inflammation I was wondering if EPM was my true cause of the inflammation in the suspensory from the get go vs. thinking it was crappy ground I was working/running on and hurt him. 

Anyone have any thoughts??

 
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FlyingJT
Reg. Jan 2014
Posted 2014-12-30 1:48 PM
Subject: RE: EPM diagnosis....now what?



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wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM  
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results

SAG 1, 5, 6 are 2

CRP/Lyme Titer 11

What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.



My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...

I was going to say you could try rebalance. Its a little cheaper and if you see improvment on that then you could spend the money to treat but since you already ordered it good luck! EPM is an exhausting, inconsistant, frustrating diagnosis. No case is the same, each horse responds differently, and it can cost owners 100's-1000's in diagnosing and treating. The first time I had to deal with it, it took my vet 3 months to decide to test for epm. My uncle, who owns race horses, suggested it as soon as I told him what was going on with the horse, but my vet couldn't find any neurological symptoms other than the muscle atrophy which he thought was from tying up. I then treated with Marquis which did nothing. Thats when I changed vets and we treated with the Orogin/Levamisole. Since then I have been using it or Diclazuril, which works very well too, to treat with. Look through all the EPM threads on BHW, there is loads of information and every story is different. Good Luck!
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wyoming barrel racer
Reg. Apr 2006
Posted 2014-12-30 1:56 PM
Subject: RE: EPM diagnosis....now what?


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FlyingJT - 2014-12-30 12:48 PM
wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM  
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results
SAG 1, 5, 6 are 2
CRP/Lyme Titer 11
What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.

My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...
I was going to say you could try rebalance. Its a little cheaper and if you see improvment on that then you could spend the money to treat but since you already ordered it good luck! EPM is an exhausting, inconsistant, frustrating diagnosis. No case is the same, each horse responds differently, and it can cost owners 100's-1000's in diagnosing and treating. The first time I had to deal with it, it took my vet 3 months to decide to test for epm. My uncle, who owns race horses, suggested it as soon as I told him what was going on with the horse, but my vet couldn't find any neurological symptoms other than the muscle atrophy which he thought was from tying up. I then treated with Marquis which did nothing. Thats when I changed vets and we treated with the Orogin/Levamisole. Since then I have been using it or Diclazuril, which works very well too, to treat with. Look through all the EPM threads on BHW, there is loads of information and every story is different. Good Luck! I looked at Rebalance on line and it is backordered everywhere. Can vets still get it? Also do I just keep treating and treating or when do I know when to try something new or if no change just chalk it up to it is a leg injury vs EPM?
I AM LOST!!! :

Is
Orogin/Levamisole the same thing? We actually planned to order as soon as the results came back, but since he has no clue what he is ordering, he couldn't find Orogin by that name in his supply book. The horse was really progressing just being back home, on ulcer supplements, treating that ligament and rest. So I told him not to worry about it for now.

Now I think I will go ahead and treat and hope for something. On one hand I want him to improve aned quit resting his hind legs and doing the odd things, but then that would mean it is actually EPM. But on the other hand, if it doesn't fix anything, then I am back to square one not knowing what the hell is wrong with him.


Edited by wyoming barrel racer 2014-12-30 1:58 PM
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RunNbarrels
Reg. Nov 2008
Posted 2014-12-30 2:36 PM
Subject: RE: EPM diagnosis....now what?


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 I saw improvement with my mare on the 3rd day of treatment with Origin. She seemed peppier and more herself. She had atrophy over her hind muscles and no energy at all. She just wasn't herself. She drastically improved after the Levamisole. Her muscles are back and she is looking and feeling great. I firmly believe in the Origin and Levamisole. At least I feel it worked for my mare. 

Edited by RunNbarrels 2014-12-30 2:37 PM
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FlyingJT
Reg. Jan 2014
Posted 2014-12-30 2:59 PM
Subject: RE: EPM diagnosis....now what?



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wyoming barrel racer - 2014-12-30 1:56 PM

FlyingJT - 2014-12-30 12:48 PM
wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM  
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results
SAG 1, 5, 6 are 2
CRP/Lyme Titer 11
What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.

My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...
I was going to say you could try rebalance. Its a little cheaper and if you see improvment on that then you could spend the money to treat but since you already ordered it good luck! EPM is an exhausting, inconsistant, frustrating diagnosis. No case is the same, each horse responds differently, and it can cost owners 100's-1000's in diagnosing and treating. The first time I had to deal with it, it took my vet 3 months to decide to test for epm. My uncle, who owns race horses, suggested it as soon as I told him what was going on with the horse, but my vet couldn't find any neurological symptoms other than the muscle atrophy which he thought was from tying up. I then treated with Marquis which did nothing. Thats when I changed vets and we treated with the Orogin/Levamisole. Since then I have been using it or Diclazuril, which works very well too, to treat with. Look through all the EPM threads on BHW, there is loads of information and every story is different. Good Luck!
I looked at Rebalance on line and it is backordered everywhere. Can vets still get it? Also do I just keep treating and treating or when do I know when to try something new or if no change just chalk it up to it is a leg injury vs EPM?
I AM LOST!!! :

Is
Orogin/Levamisole the same thing? We actually planned to order as soon as the results came back, but since he has no clue what he is ordering, he couldn't find Orogin by that name in his supply book. The horse was really progressing just being back home, on ulcer supplements, treating that ligament and rest. So I told him not to worry about it for now.

Now I think I will go ahead and treat and hope for something. On one hand I want him to improve aned quit resting his hind legs and doing the odd things, but then that would mean it is actually EPM. But on the other hand, if it doesn't fix anything, then I am back to square one not knowing what the hell is wrong with him.

It's the same thing, out of Pathogenes, but I treat an additional 10 days with just straight Levamisole. Levamisole was originally used as a dewormer and still is used. The vet I switched to was familiar with the research they are doing at the University of Florida and she suggested treating with the additional Levamisole. So far so good in every case I've had. I would say that if you don't see improvement within the first week of treatment than the horse probably doesn't have it. But... then again, it's a funny disease that is never the same from case to case. I would definitely think that after two treatments and no sign of improvement you are treating for the wrong thing.
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wyoming barrel racer
Reg. Apr 2006
Posted 2014-12-30 3:04 PM
Subject: RE: EPM diagnosis....now what?


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what are any side affects to watch for?
 
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FlyingJT
Reg. Jan 2014
Posted 2014-12-30 3:16 PM
Subject: RE: EPM diagnosis....now what?



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wyoming barrel racer - 2014-12-30 3:04 PM

what are any side affects to watch for?
 

I don't know if there is any. I know that Decoquinate is safe up to 40X the dose and Levamisole is safe up to 48X.
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GoMistyGo
Reg. Feb 2004
Posted 2014-12-30 11:09 PM
Subject: RE: EPM diagnosis....now what?



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Longneck - 2014-12-30 1:35 PM

wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM
wyoming barrel racer - 2014-12-30 12:26 PM
FlyingJT - 2014-12-30 11:13 AM
Longneck - 2014-12-30 9:35 AM
FlyingJT - 2014-12-30 9:29 AM Start treating right away! don't wait for the vitamin E to come in, it's not going to effect the drugs either way. Keep him on the vitamin E for as long as you can. You might also find another supplement to help with inflammation along with the vitamin E. I've heard people talk about Duralactin, but I haven't done any research on it so i'm not sure if it works or not.
Thanks!  I have an inflammation blend in his THE blend, I think it helped with his suspensories so hopefully it'll keep helping with this...... Do you think I should give him some bute for a couple of days until the Orogin gets in? 
It most certainly wouldn't hurt. 2 grams a day. I'm all for anything that will give the horse the upper hand on the EPM. And remember to give him time after treatment to allow his immune system to rebound. Same goes for when you bring him back to full work. Slow!
How long do you give the Orogin/Oroquin-10 and what is a schedule to bring them back? Mine has literally been hanging out in the corral since August. I planned to give his ligament off until at least Spring-April/May. Then if he vet checks out I was going to send him off for another 30 days riding. 
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results

SAG 1, 5, 6 are 2

CRP/Lyme Titer 11

What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.



My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...

I am in the same boat as you... when I read that EPM causes inflammation I was wondering if EPM was my true cause of the inflammation in the suspensory from the get go vs. thinking it was crappy ground I was working/running on and hurt him. 

Anyone have any thoughts??

 

Interesting thought... My mare has been off most of the year for various unexplainable ailments... However EPM was one of them... Had a very extensive and expensive work up last week and we also have a suspensory injury....
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rachellyn80
Reg. Jan 2004
Posted 2014-12-31 10:44 AM
Subject: RE: EPM diagnosis....now what?



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ReBalance won't take care of EPM completely.  It's $75 a bottle and you have to give 30cc's orally for a month.  The Pathogenes blood test is $60 and the Orogin treatment is one pill a day for 10 days for $200.  You can't afford to mess around with EPM.  If it's suspected in the slightest way get them tested and treated.  I am currently treating 3 head and will be testing 3 more soon.

You can't count on vets to catch it.  Many don't have enough experience with EPM and only see it once it's progressed to the point that it's obvious.  EPM does not come on quickly like West Nile or other diseases, from what I've seen it's very subtle and you have to know what is normal and what is not for your horse.  One of the first things that we've noticed is right rear lameness and spooking or shying away from things that normally don't bother them...depression, odd gaits, etc.  There are so many ways for it to present itself... 
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GoMistyGo
Reg. Feb 2004
Posted 2014-12-31 11:09 AM
Subject: RE: EPM diagnosis....now what?



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rachellyn80 - 2014-12-31 10:44 AM

ReBalance won't take care of EPM completely.  It's $75 a bottle and you have to give 30cc's orally for a month.  The Pathogenes blood test is $60 and the Orogin treatment is one pill a day for 10 days for $200.  You can't afford to mess around with EPM.  If it's suspected in the slightest way get them tested and treated.  I am currently treating 3 head and will be testing 3 more soon.

You can't count on vets to catch it.  Many don't have enough experience with EPM and only see it once it's progressed to the point that it's obvious.  EPM does not come on quickly like West Nile or other diseases, from what I've seen it's very subtle and you have to know what is normal and what is not for your horse.  One of the first things that we've noticed is right rear lameness and spooking or shying away from things that normally don't bother them...depression, odd gaits, etc.  There are so many ways for it to present itself... 

I agree! EPM is a very odd disease and does what it wants. My mare had an extensive work up by an older, very experienced equine vet in the spring. She passed a complete neurological exam. I insisted on the EPM test just to rule it out for sure. It came back with a strong positive. Vet was amazed!!!
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wyoming barrel racer
Reg. Apr 2006
Posted 2014-12-31 11:13 AM
Subject: RE: EPM diagnosis....now what?


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rachellyn80 - 2014-12-31 9:44 AM ReBalance won't take care of EPM completely.  It's $75 a bottle and you have to give 30cc's orally for a month.  The Pathogenes blood test is $60 and the Orogin treatment is one pill a day for 10 days for $200.  You can't afford to mess around with EPM.  If it's suspected in the slightest way get them tested and treated.  I am currently treating 3 head and will be testing 3 more soon.

You can't count on vets to catch it.  Many don't have enough experience with EPM and only see it once it's progressed to the point that it's obvious.  EPM does not come on quickly like West Nile or other diseases, from what I've seen it's very subtle and you have to know what is normal and what is not for your horse.  One of the first things that we've noticed is right rear lameness and spooking or shying away from things that normally don't bother them...depression, odd gaits, etc.  There are so many ways for it to present itself... 
I'm glad I have some on the way now. My gelding started to not finish his grain this past 10 days or so. He will grab a bite and walk back out of the barn to look around and act nervous at things. He does act a bit depressed but I don't know how much of that was from being cooped up in the corral for the ligament deal. He started to act much better once we treated his leg. That is what threw us off the EPM trail. I'm just going to treat for it and see what happens. As it is now, he isn't any good to me. I'm hoping this will give me my horse back. 

Edited by wyoming barrel racer 2014-12-31 11:14 AM
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Longneck
Reg. Mar 2004
Posted 2014-12-31 12:33 PM
Subject: RE: EPM diagnosis....now what?


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Well, the Orogin came in the mail this morning and I just gave him his first pill wedged in between a soaked alfalfa cube... He wasn't crazy about it!  I guess I'll have to smash it up and soak it so he can't pick around it.  Please keep him in your prayers.  He's been turned out from his stall rest for two weeks and he was pretty happy about his freedom, but now I can tell he's getting lethargic.  Hoping he starts to feeling better ASAP! 
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rachellyn80
Reg. Jan 2004
Posted 2014-12-31 12:48 PM
Subject: RE: EPM diagnosis....now what?



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This pills crush very easily.  I use something sticky like syrup or honey to make it stick to their feed.  I haven't had any trouble getting them to eat it. 
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wyoming barrel racer
Reg. Apr 2006
Posted 2014-12-31 1:37 PM
Subject: RE: EPM diagnosis....now what?


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rachellyn80 - 2014-12-31 11:48 AM This pills crush very easily.  I use something sticky like syrup or honey to make it stick to their feed.  I haven't had any trouble getting them to eat it. 

Can you crush it and mix it in a bucket of alfalfa/beet pellets soaked? I give my guy that in the mornings when it is cold. I can do it daily so he will eat it. He's horrible to give anything by syringe. He can clamp his jaws like a steel vise. Does it hurt for it to be spread around in that much feed, maybe it is a dumb question but I don't want to waste it if he needs to comsume it mostly all together. 
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rachellyn80
Reg. Jan 2004
Posted 2014-12-31 1:40 PM
Subject: RE: EPM diagnosis....now what?



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I don't know if it hurts anything... I just make sure I give mine a small amount of feed with the medicine and then give them the rest of their feed after they finish. 
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countrygirl2006
Reg. Jun 2005
Posted 2014-12-31 1:48 PM
Subject: RE: EPM diagnosis....now what?


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If you have trouble with one eating it mixed in their grain, Orogin desolves very quickly in liquid. I put the pill in a syringe and filled it with some type of juice, then just squirt it in her mouth with the syringe. She's an extremely picky eater, so this is what I found that works.

I treated with Orogin last May/June and she's been great ever since. She was out only a 2 or 3 months from competing. I had her examed after we finished treatment and starting lightly exercising her the following week per vets recommendation. When legging her up, I started out pretty slow with mostly long trotting and some loping only in straight lines. After about a month, I just went back to our normal routine and was back to running soon.

I am going back to my vet next month, 5 hour haul, and thought about having them pull blood again just for my peace of mind. Plus I was going to pick his brain on relapses and how/what to do to prevent them. Anyone have any advice on preventing relapses?  
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wyoming barrel racer
Reg. Apr 2006
Posted 2014-12-31 1:49 PM
Subject: RE: EPM diagnosis....now what?


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rachellyn80 - 2014-12-31 12:40 PM I don't know if it hurts anything... I just make sure I give mine a small amount of feed with the medicine and then give them the rest of their feed after they finish. 

I'll just do that, give a small amount and the the rest after I know he ate the pill. He's not picky so hopefully it won't be a problem 
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streakysox
Reg. Jul 2008
Posted 2014-12-31 2:14 PM
Subject: RE: EPM diagnosis....now what?



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wyoming barrel racer - 2014-12-30 1:56 PM

FlyingJT - 2014-12-30 12:48 PM
wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM  
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results
SAG 1, 5, 6 are 2
CRP/Lyme Titer 11
What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.

My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...
I was going to say you could try rebalance. Its a little cheaper and if you see improvment on that then you could spend the money to treat but since you already ordered it good luck! EPM is an exhausting, inconsistant, frustrating diagnosis. No case is the same, each horse responds differently, and it can cost owners 100's-1000's in diagnosing and treating. The first time I had to deal with it, it took my vet 3 months to decide to test for epm. My uncle, who owns race horses, suggested it as soon as I told him what was going on with the horse, but my vet couldn't find any neurological symptoms other than the muscle atrophy which he thought was from tying up. I then treated with Marquis which did nothing. Thats when I changed vets and we treated with the Orogin/Levamisole. Since then I have been using it or Diclazuril, which works very well too, to treat with. Look through all the EPM threads on BHW, there is loads of information and every story is different. Good Luck!
I looked at Rebalance on line and it is backordered everywhere. Can vets still get it? Also do I just keep treating and treating or when do I know when to try something new or if no change just chalk it up to it is a leg injury vs EPM?
I AM LOST!!! :

Is
Orogin/Levamisole the same thing? We actually planned to order as soon as the results came back, but since he has no clue what he is ordering, he couldn't find Orogin by that name in his supply book. The horse was really progressing just being back home, on ulcer supplements, treating that ligament and rest. So I told him not to worry about it for now.

Now I think I will go ahead and treat and hope for something. On one hand I want him to improve aned quit resting his hind legs and doing the odd things, but then that would mean it is actually EPM. But on the other hand, if it doesn't fix anything, then I am back to square one not knowing what the hell is wrong with him.
[/quote



I just got some from my vet last week. Don't know where they get theirs. My vet is located near LA Downs. Rebalance is not the same thing as Oroquin. Rebalance is pyrimethamine.


Just for curiosity do you have barn cats? I used the human prescription for a horse with EPM about 1992---no one knew what EPM was and a very astute vet figured it out. The brand name drug Deraprim was what we gave my horse. It is used to treat toxoplasmosis that people get from dirty kitty litter pans. The vet I use now and I were having a dicussion about barn cats peeing and pooping in the hay since similar protozoans are responsible for both illnesses. Around here we blame EPM on possum poop---trust me, I have plenty of possums. Possums are no real common in Northern states.

Baycox (toltrazuril) is a other option. I know my vet gets that out of Canada. Runs about $300. I gave that to a yearling last summer and results were excellent. I have also used it on my horse that seems to have a chronic case EPM. He gets around of rebalance every 4-6 months now.






Edited by streakysox 2014-12-31 2:44 PM
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rachellyn80
Reg. Jan 2004
Posted 2014-12-31 2:19 PM
Subject: RE: EPM diagnosis....now what?



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streakysox - 2014-12-31 2:14 PM
wyoming barrel racer - 2014-12-30 1:56 PM
FlyingJT - 2014-12-30 12:48 PM
wyoming barrel racer - 2014-12-30 1:30 PM
FlyingJT - 2014-12-30 11:58 AM  
10 days and then you usually follow up with levamisole for another 10 days. I don't think there is really a schedule to bring them back you just want to do it slow so that you don't add to much stress. Stress, pushing them to hard to fast, can be a trigger for relapse. Once a horse gets it, some believe a majority of horses already have it just don't show signs because the protozoa is in active until triggered, they will continue to carry it and always have a chance to relapse. From your other post, what makes you think he has it if the tests have come back negative?
Per Pathogenes results

SAG 1, 5, 6 are 2

CRP/Lyme Titer 11

What we recommend: Use Orogin to determine treatment response, then recheck 10 days post treatement. This was from end of Aug. I called them as the results didn't say one thing or another. Kind of a try and treat and see. They basically told me to treat if I wanted, but the results didn't show he had EPM.



My vet is a good guy here, but EPM is so unheard of in WY most have never knowingly dealt with an EPM positive horse in their entire career. They have no advice to give. My vet is willing to order the meds for me if I want to try it. I did call today to get it on the way and also ordered Vitamin E/Folic Acid supplement and will use the THE EPM one. He rests a hind leg a lot, has since the front foot injury so I am unsure if one leads to the other or...
I was going to say you could try rebalance. Its a little cheaper and if you see improvment on that then you could spend the money to treat but since you already ordered it good luck! EPM is an exhausting, inconsistant, frustrating diagnosis. No case is the same, each horse responds differently, and it can cost owners 100's-1000's in diagnosing and treating. The first time I had to deal with it, it took my vet 3 months to decide to test for epm. My uncle, who owns race horses, suggested it as soon as I told him what was going on with the horse, but my vet couldn't find any neurological symptoms other than the muscle atrophy which he thought was from tying up. I then treated with Marquis which did nothing. Thats when I changed vets and we treated with the Orogin/Levamisole. Since then I have been using it or Diclazuril, which works very well too, to treat with. Look through all the EPM threads on BHW, there is loads of information and every story is different. Good Luck!
I looked at Rebalance on line and it is backordered everywhere. Can vets still get it? Also do I just keep treating and treating or when do I know when to try something new or if no change just chalk it up to it is a leg injury vs EPM?

I AM LOST!!! :



Is
Orogin/Levamisole the same thing? We actually planned to order as soon as the results came back, but since he has no clue what he is ordering, he couldn't find Orogin by that name in his supply book. The horse was really progressing just being back home, on ulcer supplements, treating that ligament and rest. So I told him not to worry about it for now.



Now I think I will go ahead and treat and hope for something. On one hand I want him to improve aned quit resting his hind legs and doing the odd things, but then that would mean it is actually EPM. But on the other hand, if it doesn't fix anything, then I am back to square one not knowing what the hell is wrong with him.
I just got some from my vet last week. Don't know where they get theirs. My vet is located near LA Downs.
www.pathogenes.com   Orogin is not FDA approved.  You have to order it through Pathogenes and they will only send it to you with a blood test.

ReBalance is not a fix.

Orogin and Neuroquel (Levamisole) are two different drugs.  You can read everything you need to know about them including pricing on the Pathogenes website.

Dr. White at Sallisaw is who I use for EPM treatment and testing.  
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streakysox
Reg. Jul 2008
Posted 2014-12-31 2:57 PM
Subject: RE: EPM diagnosis....now what?



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From what I have read àbout Oroquin 10. The drug company is doing their testing at your expense. You have to have the horse tested at your expense, then buy the drug. After administering the drug, you pay to have your horse tested and send them the results so they can obtain their results.

The human drug that is the same as Rebalance (pyrimethamine) was what I used to treat a horse in 1992 because this is all the vet and I could find to treat the horse with. It cured it at the time. I have been dealing with EPM for about 22 years now in different horses.

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