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Cloning Frenchman guy

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Last activity 2017-03-01 5:58 PM
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streakysox
Reg. Jul 2008
Posted 2017-03-01 2:14 PM
Subject: RE: Cloning Frenchman guy



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Kaye - 2017-03-01 11:51 AM

OregonBR - 2017-03-01 10:07 AM
Kaye - 2017-03-01 7:28 AM ย There also was a bunch of racing mules that did not perform like the original. (You can probably google it still) Maybe an issue with nature vs nurture? I know there was a big argument with mitochondrial DNA, but I see that some how they matched the FG clones mitochondrial DNA too. Maybe it's advancements in science. From what I read it a different company that cloned the polo ponies.ย 
The only way to "match" the MtDNA is to get an egg from the same female family to use for the shell of the egg. MtDNA comes from the egg shell and is only passed from the tail female family through females. AQHA's DNA test to prove parentage is unable to determine the difference between a clone and his original. There is testing that can tell the difference between them but not the one AQHA uses. Once a foal is produced using the semen from the clone or the original there is no test to tell the difference because the MtDNA is lost. This is not the case with female clones. They will pass on their MtDNA to all their foals. That's also a problem because that MtDNA is important genetic material that when a clone is made may have come from any type of mare. Since the cloning industry gets their material for the eggs from slaughter mares, who knows what they are.

ย They must have used FG's sister then, because they are promoting it carries the exact mitochondrial DNA.ย 

Mitochondrial DNA is found in the MITOCHONDRIA. That could very well be why it is called mitochondrial DNA. (mtDNA) It does carry the maternal side of the DNA. In cloning the DNA is removed from the oocyte or egg and the donor's nuclear DNA is placed in the oocyte. Since mtDNA is responsible for energy production, it doesn't have a lot to do with the inherited traits. Nuclear DNA is found in the nucleus of the cell and is responsible for cell division and replication or duplication of the genetic material. Yes, there is nuclear DNA from the female also.

Here is a pretty good article on the cloning process

http://www.allaboutcutting.com/images/glo-images/PDFs/Cloning%20pdf...


Edited by streakysox 2017-03-01 2:17 PM
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Blake Russell
Reg. Jun 2014
Posted 2017-03-01 5:58 PM
Subject: RE: Cloning Frenchman guy



Pres. ViaGen


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Just to clarify a few things. Yes, same company cloned the polo horses. Same proven process. MtDNA is not transmitted by sires, so mtDNA haplotype in sires for breeding is irrelevant. ViaGen does often test mtDNA haplotype for clients and can produce foals of same haplotype if requested. ViaGen has tested hundreds of horses for mtDNA haplotype and understands the lack of association of mtDNA haplotype with performance. Female lines are important because of their chromosomal DNA contribution to their foals which include sex linked traits. Those who refuse to breed to clones for AQHA Registry have a valid point. Alternative is to register in ADNA to have DNA tested pedigree but this does not qualify a horse for AQHA competitions. Every horses performance is a combination of DNA x Environment (nature vs nurture) however breeding value is purely DNA. If the donor sire is a proven producer, then the cloned stallion is proven by definition. Just as many of top barrel sires are not proven in the arena, however, their offspring proved their genetic value.
I hope this helps someone who is honestly trying to understand the technology.
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